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产品数:86101
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已选条件
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TQ0068NVP-LCQ195NVP-LCQ195,AT-9311,NVPLCQ195,NVP-LCQ-195,inhibit,Cyclin dependent kinase,Inhibitor,AT 9311
NVP-LCQ195 (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).
价 格:¥电议型 号:TQ0068产 地:中国大陆
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T8242Sabineneskeletal muscle atrophy,L6 cells,bicyclic monoterpene,Makino essential oil,Chrysanthemum bor
Sabinene is a natural product that has antifungal and anti-inflammatory properties
价 格:¥电议型 号:T8242产 地:中国大陆
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T6612NU6027inhibit,Ataxia telangiectasia mutated,Cyclin dependent kinase,ATM/ATR,NU 6027,cytotoxicity,NU6
NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-aminopurine-based inhibitors.
价 格:¥电议型 号:T6612产 地:中国大陆
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T8378AS2863619Cyclin dependent kinase,AS2863619,STAT,AS 2863619,Inhibitor,inhibit,CDK,AS-2863619
AS2863619 is an orally active inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of 0.61 nM and 4.28 nM, respectively).
价 格:¥电议型 号:T8378产 地:中国大陆
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T8916WEE1-IN-3WEE1IN3,cycle,Inhibitor,inhibit,cell,Wee1,WEE-1-IN-3,WEE1 IN 3,Anticancer
JUN76288 is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.
价 格:¥电议型 号:T8916产 地:中国大陆
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TQ0266MSC2530818Cyclin dependent kinase,Inhibitor,CDK,MSC2530818,inhibit,MSC 2530818,MSC-2530818
MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).
价 格:¥电议型 号:TQ0266产 地:中国大陆
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T2403Bromfenac sodium hydrateinhibit,COX,Bromfenac sodium hydrate,ocular inflammation,HLEC-B3,Cyclooxygen
Bromfenac Sodium Sesquihydrate is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II), an enzyme which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins (PG). By inhibiting PG formation, bromfenac is able to inhibit PG-induced inflammation, thereby preventing vasodilation, leukocytosi
价 格:¥电议型 号:T2403产 地:中国大陆
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T9042Teriflunomide impurity 3inhibit,NSAID,COX-1,analgesic,Cyclooxygenase,Inhibitor,COX,Teriflunomide imp
Teriflunomide impurity 3 is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).
价 格:¥电议型 号:T9042产 地:中国大陆
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T6968RiociguatInhibitor,inhibit,BAY-632521,Riociguat,Guanylate Cyclase,BAY632521
Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.
价 格:¥电议型 号:T6968产 地:中国大陆
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T9626CycloleucineIonotropic glutamate receptors,inhibit,glycine,NMDA,cytostatic,nucleic,Inhibitor,Cyclole
Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of S-adenosyl-methionine mediated methylation with anxiolytic and cytostatic effects.
价 格:¥电议型 号:T9626产 地:中国大陆
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TN1723HamaudolInhibitor,COX,Hamaudol,Cyclooxygenase,inhibit
Hamaudol is a chromone isolated from Saposhnikovia divaricata,has analgesic and anti-inflammary activities, it showed inhibitory activity on COX-1 and COX-2 activities with values of 0.30, 0.57 mM, respectively.
价 格:¥电议型 号:TN1723产 地:中国大陆
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T8293γ-TocopherolInhibitor,γ-Tocopherol,γTocopherol,COX,antiinflammatory,Cyclooxygenase,Vitamin,γ Tocophe
(+)-γ-Tocopherol is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.
价 格:¥电议型 号:T8293产 地:中国大陆
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T85013-?Phenyl-?N-?[1-?(phenylmethyl)?-?4-?piperidinyl]?-tricyclo[3.3.1.13,?7]?decane-?1-?carboxamide3?Ph
3- Phenyl- N- [1- (phenylmethyl) - 4- piperidinyl] -tricyclo[3.3.1.13, 7] decane- 1- carboxamide with antiviral activity against Ebola virus that targets the surface-exposed glycoprotein and inhibits viral entry into host cells. In vitro studies in Vero cells revealed the compound inhibits the viral replication with EC50 of 0.38 μM.
价 格:¥电议型 号:T8501产 地:中国大陆
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T60037SR15006growth,inhibit,KLF5,SR 15006,Krüppel-like factor,SR15006,colorectal cancer cells,cycle,Inhibi
SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).
价 格:¥电议型 号:T60037产 地:中国大陆
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TN71951,8-Diazabicyclo[5.4.0]undec-7-ene
1,8-Diazabicyclo[5.4.0]undec-7-ene is a marine derived natural products found in Niphates digitalis.
价 格:¥电议型 号:TN7195产 地:中国大陆
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T4039BIBB 515BIBB 515,Inhibitor,OSC,inhibit,cyclase,effect,metabolism,LDL,BIBB-515,2,3-oxidosqualene,BIBB
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2, 3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. Total cholesterol was reduced by 19% in normolipemic hamsters at a dose of 55 mg/kg/day for 11 days and 25% in hyperlipemic
价 格:¥电议型 号:T4039产 地:中国大陆
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T6837FlavopiridolHMR1275,inhibit,L86-8275,CDK,Cyclin dependent kinase,Inhibitor,Autophagy,HMR 1275,Human
Flavopiridol (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2.
价 格:¥电议型 号:T6837产 地:中国大陆
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T7539O6-Benzylguaninepancreatic,DNA/RNA Synthesis,transcriptional,PARP1,p53,inhibit,cyclin,O-6-Benzylguan
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
价 格:¥电议型 号:T7539产 地:中国大陆
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T8259Doxycycline monohydrateinhibit,Doxycycline,Inhibitor,MMP,Matrix metalloproteinases,Doxycycline monoh
Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)
价 格:¥电议型 号:T8259产 地:中国大陆
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T8236RHC 80267COX,mAChR,Platelet,mono- acylglycerol acyltransferase,Cyclooxygenase,Acyltransferase,Phosph
RHC 80267 is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)
价 格:¥电议型 号:T8236产 地:中国大陆