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T26981Ceralasertib formate;化合物 T26981Ceralasertib|||AZD-6738|||AZD 6738|||AZD6738;Ceralasertib|||AZD-6738|
Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling, and results in the inhibition of DNA damage checkpoint activation, disruption of DNA damage repair, and the induction of tumor cell apoptosis.
价 格:¥电议型 号:T26981产 地:中国大陆
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T26721AZD6703 free base;化合物 T26721AZD-6703|||AZD6703|||AZD 6703;AZD-6703|||AZD6703|||AZD 6703
AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase 14 (MAPK14).
价 格:¥电议型 号:T26721产 地:中国大陆
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T26720AZD-6605;化合物 T26720AZ11920155|||AZ-11920155|||AZD6605;AZ11920155|||AZ-11920155|||AZD6605
AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13.
价 格:¥电议型 号:T26720产 地:中国大陆
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T26719AZD6538;化合物 AZD6538AZD 6538|||AZD-6538;AZD 6538|||AZD-6538
AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer´s disease.
价 格:¥电议型 号:T26719产 地:中国大陆
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T26718AZD6370;化合物 T26718AZD-6370|||AZD 6370;AZD-6370|||AZD 6370
AZD-6370 is a glucokinase activator. AZD-6370 decreases fasting and postprandial glucose in type 2 diabetes mellitus patients with effects influenced by dosing regimen and food. AZD-6370 do not affect the central counterregulatory response to hypoglycemia in healthy males.
价 格:¥电议型 号:T26718产 地:中国大陆
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T23960Dacuronium;化合物 T23960UNII-VD6L56ZVX1|||17-Hydroxypancuronium|||Androstane, piperidinium deriv;UNII-V
Dacuronium is a new steroidal drug of neuromuscular blocking properties. Dacuronium produced a competitive type of neuromuscular block with a potency of approximately one-tenth that of tubocurarine and one-fiftieth that of pancuronium.
价 格:¥电议型 号:T23960产 地:中国大陆
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T23889CID-663143;化合物CID-663143CID663143;CID663143
CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.
价 格:¥电议型 号:T23889产 地:中国大陆
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T21715BRD6688;化合物BRD6688BRD6688
BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes
价 格:¥电议型 号:T21715产 地:中国大陆
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T21307Heptaplatin化合物 T21307NSC644591 NSCD644591 SKI2053R|||Heptaplatin Sunpla|||HTP
Heptaplatin, a new platinum derivative with anticancer activity, is used against various cancer cell lines, including cisplatin-resistant cancer cell lines. It has been reported to have a response rate of 17% as a single agent, and tolerable toxicity in the treatment of advanced gastric cancer.
价 格:¥电议型 号:T21307产 地:中国大陆
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T2088APD668;化合物APD 668APD 668;APD 668
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
价 格:¥电议型 号:T2088产 地:中国大陆
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T19551Rosuvastatin D6 Calcium;化合物 T19551Rosuvastatin D6 Calcium
Rosuvastatin D6 Calcium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
价 格:¥电议型 号:T19551产 地:中国大陆
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T19474Netupitant N-oxide D6;化合物 T19474Netupitant N-oxide D6
Netupitant N-oxide D6 is a Netupitant metabolite, is the deuterium labeled Netupitant N-oxide.
价 格:¥电议型 号:T19474产 地:中国大陆
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T19452N-desmethyl Netupitant D6;化合物 T19452N-desmethyl Netupitant D6
N-desmethyl Netupitant D6 is the deuterium labeled N-desmethyl Netupitant, which is a Netupitant metabolite.
价 格:¥电议型 号:T19452产 地:中国大陆
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T19449N-desmethyl Enzalutamide D6;化合物 T19449N-desmethyl MDV 3100 D6;N-desmethyl MDV 3100 D6
N-desmethyl Enzalutamide D6 is a deuterium labeled N-desmethyl Enzalutamide.
价 格:¥电议型 号:T19449产 地:中国大陆
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T19447N-Demethyl Ivabradine D6 Hydrochloride;化合物 T19447N-Demethyl Ivabradine D6 Hydrochloride
N-Demethyl Ivabradine D6 Hydrochloride salt is the deuterium labeled N-Demethyl Ivabradine, which is a Ivabradine metabolite.
价 格:¥电议型 号:T19447产 地:中国大陆
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T19434Monohydroxy Netupitant D6;化合物 T19434Monohydroxy Netupitant D6
Monohydroxy Netupitant D6 is a metabolite of Netupitant.
价 格:¥电议型 号:T19434产 地:中国大陆
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T19312Erlotinib-d6 hydrochloride;化合物 T19312CP-358774 D6 hydrochloride|||NSC 718781 D6 hydrochloride|||Erlo
Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.
价 格:¥电议型 号:T19312产 地:中国大陆
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T19311Enzalutamide carboxylic acid D6;化合物 T19311MDV3100 carboxylic acid D6;MDV3100 carboxylic acid D6
Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide. Enzalutamide carboxylic acid D6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid).
价 格:¥电议型 号:T19311产 地:中国大陆
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T19305Eldecalcitol-d6;化合物 T19305Eldecalcitol-d6
Eldecalcitol is an orally active analogue of active vitamin D used in the treatment of osteoporosis. Eldecalcitol-d6 is the deuterium labeled Eldecalcitol.
价 格:¥电议型 号:T19305产 地:中国大陆
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T19187Aliskiren D6 hemifumarate;化合物 T19187CGP 60536 D6 hemifumarate|||SPP 100 D6 hemifumarate|||CGP60536B
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).
价 格:¥电议型 号:T19187产 地:中国大陆