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T36359Dios-Arg (trifluoroacetate salt)Dios-Arg (trifluoroacetate salt)DiosArg (trifluoroacetate salt)|||Di
Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4. Dios-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence and absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the cav
价 格：￥电议型 号：T36359产 地：中国大陆
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T36350Cho-Arg (trifluoroacetate salt)Cho-Arg (trifluoroacetate salt)ChoArg (trifluoroacetate salt)|||Cho A
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the cav
价 格：￥电议型 号：T36350产 地：中国大陆
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T36342Ac-LEHD-AMC (trifluoroacetate salt)；Ac-LEHD-AMC (trifluoroacetate salt)Ac-LEHD-AMC (trifluoroacetate
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9.[1] Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
价 格：￥电议型 号：T36342产 地：中国大陆
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T36340Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt)；Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gl
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1). Enzymatic peptide hydrolysis disrupts the Abz:EDDnp donor-acceptor pair allowing fluorescence measurement of Abz (ex = 320 nm; em = 420 nm).
价 格：￥电议型 号：T36340产 地：中国大陆
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T36338AAF-CMK (trifluoroacetate salt)；AAF-CMK (trifluoroacetate salt)AAF-CMK (trifluoroacetate salt)
Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at 50 μM.
价 格：￥电议型 号：T36338产 地：中国大陆
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T36095Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt)；Histone H2BK12ac (1-22)-GGK-biotin
Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt) can be used in related research in the field of life sciences, and its product number is T36095.
价 格：￥电议型 号：T36095产 地：中国大陆
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T36019PKA Inhibitor (5-24) (trifluoroacetate salt)；PKA Inhibitor (5-24) (trifluoroacetate salt)PKA Inhibit
PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki= 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein.1It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite.1The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr235and Phe239form a sandwich-like structure with residue Phe10of PKI (5-24).2
价 格：￥电议型 号：T36019产 地：中国大陆
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T35955PAR2 (1-6) amide (human) (trifluoroacetate salt)；PAR2 (1-6) amide (human) (trifluoroacetate salt)PAR
PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide prod
价 格：￥电议型 号：T35955产 地：中国大陆
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T35867TRAP-6 Peptide (trifluoroacetate salt)；TRAP-6 Peptide (trifluoroacetate salt)TRAP-6 Peptide (trifluo
TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 μM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration.
价 格：￥电议型 号：T35867产 地：中国大陆
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T35858Adrenomedullin (22-52) (human) (trifluoroacetate salt)；Adrenomedullin (22-52) (human) (trifluoroacet
Adrenomedullin (22-52) is a C-terminal fragment of adrenomedullin (1-52) .
价 格：￥电议型 号：T35858产 地：中国大陆
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T35836PMX-205 (trifluoroacetate salt)；PMX-205 (trifluoroacetate salt)PMX-205 (trifluoroacetate salt)
PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50= 31 nM).1It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma.2,3PMX-205 is also brain penetrant and reduces neuroinflammation and neurodegeneration in an animal model of Alzheimer´s disease.4
价 格：￥电议型 号：T35836产 地：中国大陆
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T35835FFN-102 (trifluoroacetate salt)；FFN-102 (trifluoroacetate salt)FFN-102 (trifluoroacetate salt)
FFN-102 (trifluoroacetate salt) is a synthetic biogenic neurotransmitter analog with pH-dependent fluorescence and electroactivity.
价 格：￥电议型 号：T35835产 地：中国大陆
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T35815Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)；Vildagliptin carboxylic acid metabol
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. Vildagliptin carboxylic acid metabolite has an IC50 value of 477 μM for DPP-4 in human Caco-2 cells. It is formed from hydrolysis of the cyano group on vildagliptin.
价 格：￥电议型 号：T35815产 地：中国大陆
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T35814Urocortin III (human) (trifluoroacetate salt)；Urocortin III (human) (trifluoroacetate salt)Urocortin
Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.
价 格：￥电议型 号：T35814产 地：中国大陆
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T35794Kisspeptin-54 (human) (trifluoroacetate salt)；Kisspeptin-54 (human) (trifluoroacetate salt)Kisspepti
Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gene KISS-1. Kisspeptin-54 induces calcium mobilization in CHO-K1 cells expressing rat and human receptors (EC50s = 1.39 and 5.47 nM, respectively). It also induces arachidonic acid release in CHO cells expressing rat and human GPR54 in a concentration-dependent manner. Kisspeptin-5
价 格：￥电议型 号：T35794产 地：中国大陆
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T35787Obestatin (human) (trifluoroacetate salt)；Obestatin (human) (trifluoroacetate salt)Obestatin (human)
Obestatin is a 23 amino acid peptide hormone with a conserved C-terminal glycine residue and amidation site that is formed by cleavage of the ghrelin and obestatin prepropeptide.1It binds to the orphan receptor GPR39 (Kd= 1 nM) and stimulates cAMP production in CHO and HEK293 cells overexpressing human GPR39. Obestatin inhibits contraction of isolated mouse jejunum muscle strips induced by ghrelin .
价 格：￥电议型 号：T35787产 地：中国大陆
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T35675SW203668 (trifluoroacetate salt)SW203668 (trifluoroacetate salt)SW-203668 (trifluoroacetate salt)|||
SW203668 is an irreversible inhibitor of stearoyl-CoA desaturase (IC50 = 54 nM). It is selectively cytotoxic to H2122, H460, HCC44, and HCC95 cell lines that express cytochrome P450 (CYP) isoform CYP4F11 over eight other cancer cell lines that lack CYP4F11 in vitro (IC50s = 22-116 and >10,000 nM, respectively) and ectopic expression of CYP4F11 in SW203668-insensitive H1155 cells results in sensitization to SW203668.
价 格：￥电议型 号：T35675产 地：中国大陆
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T35669Neuromedin C (trifluoroacetate salt)；Neuromedin C (trifluoroacetate salt)Neuromedin C (trifluoroacet
Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide corresponding to the GRP amino acids 18-27. It inhibits GRP and bombesin binding to rat pancreatic membranes (IC50s = 0.4 and 2.2 nM, respectively), which can be reduced by sodium chloride and guanylyl imidodiphosphate . Neuromedin C induces scratching and mast cell degranulatio
价 格：￥电议型 号：T35669产 地：中国大陆
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T35663Cortistatin-29 (rat) (trifluoroacetate salt)；Cortistatin-29 (rat) (trifluoroacetate salt)Cortistatin
Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Cortistatin mRNA is expressed in the human brain and in interneurons of the rat hippocampus and cerebral cortex. Cortistatin-29 binds to somatostatin (SST) receptors with IC50 values of 2.8, 7.1, 0.2, 3, and 13.7 nM for SST1-
价 格：￥电议型 号：T35663产 地：中国大陆
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T35662Cortistatin-29 (1-13) (rat) (trifluoroacetate salt)；Cortistatin-29 (1-13) (rat) (trifluoroacetate sa
Cortistatin-29 (1-13) is a neuropeptide and cleavage product of cortistatin-29 , which is a cleavage product of procortistatin. Cortistatin-29 (1-13) corresponds to the first 13 amino acids of cortistatin-29.
价 格：￥电议型 号：T35662产 地：中国大陆
