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T10625L(Rac)-IBT6A hydrochloride (1412418-47-3 free base);化合物 T10625L(Rac)-IBT6A hydrochloride;(Rac)-IBT6A
(Rac)-IBT6A hydrochloride is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib. IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM).
价 格:¥电议型 号:T10625L产 地:中国大陆
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T1062Capsaicin;辣椒素Qutenza|||8-Methyl-N-vanillyl-trans-6-nonenamide|||Vanilloid|||(E)-Capsaicin|||Zostrix;
Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities.
价 格:¥电议型 号:T1062产 地:中国大陆
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T10568BMS-470539 dihydrochloride;化合物 T10568BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective agonist of the melanocortin-1 receptor (MC-1R; IC50: 120 nM; EC50: 28 nM) with anti-inflammatory properties. It does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R.
价 格:¥电议型 号:T10568产 地:中国大陆
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T10565BMS-1001 hydrochloride;化合物BMS-1001 hydrochlorideBMS-1001 hydrochloride
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes.
价 格:¥电议型 号:T10565产 地:中国大陆
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T10563LBM635 hydrochloride (1493762-74-5 free base);化合物 T10563LBM635 hydrochloride;BM635 hydrochloride
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).
价 格:¥电议型 号:T10563L产 地:中国大陆
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T1056Isoprenaline hydrochloride盐酸异丙肾上腺素NCI-c55630|||Isoproterenol hydrochloride|||Isoprenaline HCl|||盐酸异丙
Isoprenaline hydrochloride (Isoproterenol hydrochloride) is a β-adrenergic agonist with non-selective and oral activity. Isoprenaline hydrochloride dilates bronchioles and increases heart rate and cardiac output without constricting blood vessels.
价 格:¥电议型 号:T1056产 地:中国大陆
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T10550Bisindolylmaleimide X hydrochloride;化合物 T10550BIM-X hydrochloride|||Ro31-8425 hydrochloride;BIM-X hy
Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM).
价 格:¥电议型 号:T10550产 地:中国大陆
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T10543BIIL-260 hydrochloride;化合物 T10543BIIL-260 hydrochloride
BIIL-260 hydrochloride is a potent and long-acting orally active antagonist of leukotriene B4 (LTB4) receptor with anti-inflammatory activity. It has a high affinity to the LTB4 receptor on isolated human neutrophil cell membranes (Ki: 1.7 nM).
价 格:¥电议型 号:T10543产 地:中国大陆
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T10538LBI-9321 trihydrochloride;化合物 T10538LBI-9321 trihydrochloride
BI-9321 trihydrochloride is a selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist (Kd: 166 nM). BI-9321 is inactive against NSD2-PWWP1 and NSD3-PWWP2.
价 格:¥电议型 号:T10538L产 地:中国大陆
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T1053Mebeverine hydrochloride;盐酸麦皮凡林Colofac Hydrochloride|||Duspatalin Hydrochloride|||Duspatal Hydrochlo
Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut.
价 格:¥电议型 号:T1053产 地:中国大陆
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T10513Benzothiohydrazide化合物 BenzothiohydrazideBenzothiohydrazide
Benzothiohydrazide is an analog of isoniazid with anti-tuberculosis activity and can be used to isolate fungi and bacteria.
价 格:¥电议型 号:T10513产 地:中国大陆
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T10511Anti-hypertensive sulfonanilide 1;化合物 T10511Anti-hypertensive sulfonanilide 1
Anti-hypertensive sulfonanilide 1 is an antihypertensive compound.
价 格:¥电议型 号:T10511产 地:中国大陆
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T10509Xanthine oxidase-IN-1;黄嘌呤氧化酶IN14-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid;4-(3-Cyano-5
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid and nucleotide intermediates.
价 格:¥电议型 号:T10509产 地:中国大陆
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T1050Prazosin hydrochloride哌唑嗪盐酸盐Prazosin hydrochloride|||哌唑嗪盐酸盐|||Prazosin HCl|||cp-12299-1|||Peripress|
Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin hydrochloride is a synthetic piperazine derivative with hypotensive antiadrenergic properties, It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud´s syndrome, prostatic hypertrophy, and urinary retention.
价 格:¥电议型 号:T1050产 地:中国大陆
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T10491LGalidesivir hydrochloride;化合物 T10491LBCX 4430 hydrochloride|||Immucillin-A hydrochloride;BCX 4430 hy
Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.
价 格:¥电议型 号:T10491L产 地:中国大陆
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T1049Oxybutynin chloride;盐酸奥昔布宁Oxybutynin hydrochloride|||Oxybutynin HCl;Oxybutynin hydrochloride|||盐酸奥昔布
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.
价 格:¥电议型 号:T1049产 地:中国大陆
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T10486LBCI hydrochloride化合物 T10486L(E)-BCI hydrochloride
BCI hydrochloride specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI hydrochloride does not inhibit DUSP5. BCI hydrochloride is an allosteric inhibitor of dual specificity phosphatase (DUSP).
价 格:¥电议型 号:T10486L产 地:中国大陆
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T10482LBB-Cl-Amidine hydrochloride化合物 T10482LBB-Cl-Amidine hydrochloride (1802637-39-3 free base)
BB-Cl-Amidine hydrochloride is an inhibitor of peptidylarginine deminase (PAD) [1].
价 格:¥电议型 号:T10482L产 地:中国大陆
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T10468Elimusertib hydrochloride(1876467-74-1 free base);化合物 Elimusertib hydrochlorideBAY-1895344 hydrochlo
Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor activity.
价 格:¥电议型 号:T10468产 地:中国大陆
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T10462LBavisant dihydrochloride hydrate;化合物 T10462LJNJ31001074AAC;JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格:¥电议型 号:T10462L产 地:中国大陆