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  • T71586Z-VAE(OMe)-fmk；化合物 Z-VAE(OMe)-fmkZ-VAE(OMe)-fmk

    Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin´s C-terminal tail, thereby occupying the P1´ (leaving group) site, a binding site perhaps used by the unknown C-terminal extension of ubiquitin in the actual in vivo substrate(s) of UCHL1.

    价 格：￥电议型 号：T71586产 地：中国大陆

  • T71585DB03417；化合物 DB03417DB03417

    DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor.

    价 格：￥电议型 号：T71585产 地：中国大陆

  • T71584Microtubule Inhibitor 185322；化合物 Microtubule Inhibitor 185322Microtubule Inhibitor 185322

    Microtubule inhibitor 185322 is an inhibitor of microtubule assembly, inducung mitotic arrest and apoptosis of MM cells.

    价 格：￥电议型 号：T71584产 地：中国大陆

  • T71583Amlodipine hydrochloride, (R)-；化合物 Amlodipine hydrochloride, (R)-Amlodipine hydrochloride, (R)-

    Amlodipine hydrochloride, (R)-, is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vessels it lowers blood pressure. In angina, amlodipine increases blood flow to the heart muscle to relieve pain due to angina.

    价 格：￥电议型 号：T71583产 地：中国大陆

  • T71582Niguldipine Free Base；化合物 Niguldipine Free BaseNiguldipine Free Base

    Niguldipine Free Base is a calcium channel blocker and a?-adrenergic receptor antagonist and a clinical modulator of multidrug resistance.

    价 格：￥电议型 号：T71582产 地：中国大陆

  • T71581SGX393；化合物 SGX393SGX393

    SGX393 is an inhibitor of the CML mutant Bcr-AblT315I, thereby preempting in vitro resistance when combined with nilotinib or dasatinib.

    价 格：￥电议型 号：T71581产 地：中国大陆

  • T71580EBV activator C60；化合物 EBV activator C60EBV activator C60

    EBV activator C60 is an EBV activator, and a well-performing EBV lytic cycle inducer.

    价 格：￥电议型 号：T71580产 地：中国大陆

  • T7158Ombitasvir；奥比他韦ABT-267；奥比他韦|||ABT-267

    Ombitasvir (ABT-267) is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a

    价 格：￥电议型 号：T7158产 地：中国大陆

  • T71577KOS-1584；化合物 KOS-1584KOS-1584

    KOS-1584 is a second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to first-generation epothilones, this agent exhibits greater safety and efficacy with an enhanced pharmaceutical profile, including enhanced water solubility and tumor penetration,

    价 格：￥电议型 号：T71577产 地：中国大陆

  • T71558Pim-IN-14j；化合物 Pim-IN-14jPim-IN-14j

    Pim-IN-14j is a potent, highly selective, and orally bioavailable inhibitor of PIM-1 kinases.

    价 格：￥电议型 号：T71558产 地：中国大陆

  • T71525AB05831；化合物 AB05831AB05831

    AB05831, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of beta-hexosaminidase. N-Acetyl-3-hexosaminidase (HEX) is a member of lysosomal hydrolases, which catalyzes hydrolysis of terminal, non-reducing N-acetyl-|3-D-glucosamine (GlcNAc) andN-acetyl-(3-D-galactosamine (GalNAc) residues in glycoproteins, gan-gliosides, and glycosaminoglycans (GAGs). HEX, released by chondrocytes into the extracellular compartment, promotes cartilage matrix degradation.

    价 格：￥电议型 号：T71525产 地：中国大陆

  • T71505KAL-21404358；化合物 KAL-21404358KAL-21404358

    KAL-21404358 is a Novel allosteric inhibitor of K-RasG12D, binding to the P110 site of K-RasG12D, impairing the K-RasG12D interaction with B-Raf, and disrupting the RAF-MEK-ERK and the PI3K-AKT signaling pathway.

    价 格：￥电议型 号：T71505产 地：中国大陆

  • T71493AM6580；化合物 AM6580AM6580

    AM6580 is an irreversible monoacylglycerol lipase (MGL) inhibitor.

    价 格：￥电议型 号：T71493产 地：中国大陆

  • T71458Epetraborole；化合物 EpetraboroleEpetraborole

    Epetraborole is a potent and selective leucyl-tRNA synthetase inhibitor. Epetraborole was in development for the treatment of infections caused by multidrug-resistant Gram-negative pathogens.

    价 格：￥电议型 号：T71458产 地：中国大陆

  • T71358Nialamide monohydrochloride；化合物 Nialamide monohydrochlorideNialamide monohydrochloride

    Nialamide monohydrochloride is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant. It was withdrawn by Pfizer several decades ago due to the risk of hepatotoxicity.

    价 格：￥电议型 号：T71358产 地：中国大陆

  • T71348UC-773587；化合物 UC-773587UC-773587

    UC-773587 is a novel inhibitor of Ras signaling, binding to the Ras switch II interaction region of SOS1.

    价 格：￥电议型 号：T71348产 地：中国大陆

  • T71317WS1358A1 disodium；化合物 WS1358A1 disodiumWS1358A1 disodium

    WS1358A1 disodium is a potent inhibitor of renal dehydropeptidase.

    价 格：￥电议型 号：T71317产 地：中国大陆

  • T71258Dehydrodeoxy donepezil；化合物 Dehydrodeoxy donepezilDehydrodeoxy donepezil

    Dehydrodeoxy donepezil is an inhibitor of acetylcholinesterase (AChE)

    价 格：￥电议型 号：T71258产 地：中国大陆

  • T71251DS-1558；化合物 DS-1558DS-1558

    DS-1558 is a potent and orally available GPR40 agonist.DS-1558 was found to have potent glucose lowering effects during an oral glucose tolerance test in ZDF rats. DS-1558 significantly and dose-dependently improved hyperglycemia and increased insulin secretion during the oral glucose tolerance test in Zucker fatty rats, the model of insulin resistance and glucose intolerance. DS-1558 not only increased the glucose-stimulated insulin secretion by GLP-1 but also potentiated the maximum insulinog

    价 格：￥电议型 号：T71251产 地：中国大陆

  • T71210S7958；化合物 S7958S7958

    S7958 is a is a TAS2R8 antagonist. It was found to be non-mutagenic in vitro.

    价 格：￥电议型 号：T71210产 地：中国大陆

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