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T4310L2Prexasertib mesylate;化合物 T4310L2LY-2606368|||LY2606368|||LY 2606368;LY-2606368|||LY2606368|||LY 2606
Prexasertib is a potent and selective Chk1/Chk2 inhibitor. Prexasertib increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia. LY2606368 causes replication catastrophe and antitumor effects through CHK1-dependent mechanisms. Treatment of cells with LY2606368 results in the rapid appearance of TUNEL and pH2AX-positive double-stranded DNA breaks in the S-phase cell population.
价 格:¥电议型 号:T4310L2产 地:中国大陆
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T4310LPrexasertib lactate hydrate;化合物 T4310LPrexasertib monolactate monohydrate|||LY-2606368|||LY 2606368|
Prexasertib is an effective and selective Chk1/Chk2 inhibitor. Prexasertib causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms.
价 格:¥电议型 号:T4310L产 地:中国大陆
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T4310Prexasertib;化合物PrexasertibLY2606368;5-[[5-[2-(3-氨基丙氧基)-6-甲氧基苯基]-1H-吡唑-3-基]氨基]-2-吡嗪甲腈|||LY2606368
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
价 格:¥电议型 号:T4310产 地:中国大陆
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T4302iCRT3;化合物iCRT3iCRT3
iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.
价 格:¥电议型 号:T4302产 地:中国大陆
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T4248T.cruzi Inhibitor (1350920-22-7(free base));T.cruzi InhibitorT.cruzi Inhibitor (1350920-22-7(free ba
T.cruzi Inhibitor is a Trypanosoma cruzi inhibitor.
价 格:¥电议型 号:T4248产 地:中国大陆
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T4163Reparixin;瑞帕利辛DF 1681Y|||Repertaxin;DF 1681Y|||Repertaxin|||瑞帕利辛
Reparixin (Repertaxin) is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).
价 格:¥电议型 号:T4163产 地:中国大陆
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T4136Lapachol;黄钟花醌Bethabarra wood|||CI75490|||Greenhartin|||Tecomin;Bethabarra wood|||CI75490|||黄钟花醌|||Gr
Lapachol (CI75490) has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.
价 格:¥电议型 号:T4136产 地:中国大陆
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T41303Isoflupredone;异氟泼尼松Delta-Fluorocortisone|||Isoflupredona|||Isoflupredonum|||9-Fluoroprednisolone;Del
Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expression of inflammatory mediators. Isoflupredone has anti-inflammatory and immunosuppressive effects and can be used to treat a variety of musculoskeletal, allergic and systemic inflammatory diseases.
价 格:¥电议型 号:T41303产 地:中国大陆
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T41239Verrucofortine;化合物 VerrucofortineVerrucofortine
Verrucofortine has a wide range of applications in life science related research.
价 格:¥电议型 号:T41239产 地:中国大陆
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T41182Ifenprodil hemitartrate;Ifenprodil hemitartrateIfenprodil hemitartrate
Ifenprodil hemitartrate is a NMDA receptor antagonist, acting at the polyamine site. Also anα-adrenergic vasodilator.σ2ligand displaying about 3-fold selectivity overσ1sites.
价 格:¥电议型 号:T41182产 地:中国大陆
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T41163ZNL 02-096;化合物ZNL 02-096Pomalidomide-C3-adavosertib;Pomalidomide-C3-adavosertib
ZNL 02-096 (Pomalidomide-C3-adavosertib) is a rapid and selective degrader of Wee1 (IC50=3.58 nM).ZNL 02-096 selectively degrades Wee1 at submolar concentrations without damaging PLK1, a secondary target of AZD 1775.ZNL 02-096 induces degradation of Wee1 and accumulation of DNA damage in MOLT-4 cells in vitro, In vitro in MOLT-4 cells, ZNL 02-096 induced Wee1 degradation, accumulation of DNA damage, cell cycle arrest in G2/M phase and apoptosis.ZNL 02-096 showed anti-proliferative effects in 300
价 格:¥电议型 号:T41163产 地:中国大陆
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T41120Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OH;Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OHFmoc-Asn(Trt)-Thr(psi(Me,Me)p
Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide.
价 格:¥电议型 号:T41120产 地:中国大陆
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T41100Volasertib trihydrochloride伏拉塞替三盐酸盐BI6727trihydrochloride|||伏拉塞替三盐酸盐
Volasertib (BI 6727) trihydrochloride is a dihydropteridinone derivative that exhibits potent and selective inhibition of Polo-like kinase 1 (PLK1), PLK2, and PLK3. It acts as an orally active ATP-competitive inhibitor with an IC50 of 0.87 nM against PLK1. Additionally, Volasertib trihydrochloride demonstrates IC50 values of 5 nM and 56 nM against PLK2 and PLK3, respectively. Its mechanism of action includes inducing mitotic arrest and apoptosis. Furthermore, Volasertib trihydrochloride has been
价 格:¥电议型 号:T41100产 地:中国大陆
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T41067Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH;Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OHFmoc-Asn(Trt)-Ser(psi(Me,Me)p
Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide.
价 格:¥电议型 号:T41067产 地:中国大陆
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T4102Goserelin acetate;醋酸戈舍瑞林Fertilan|||ICI-118630 acetate|||Zoladex;醋酸戈舍瑞林|||Fertilan|||ICI-118630 aceta
Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
价 格:¥电议型 号:T4102产 地:中国大陆
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T40941Olmesartan lactone impurity;Olmesartan lactone impurityOlmesartan lactone impurity
Olmesartan lactone impurity is a cyclic ester impurity derived from Olmesartan, which is an angiotensin II receptor (AT1R) antagonist with potential applications in the study of high blood pressure.
价 格:¥电议型 号:T40941产 地:中国大陆
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T40915L-Aspartic acid 13C;L-Aspartic acid 13CL-Aspartic acid 13C
L-Aspartic acid 13C is a 13C labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.
价 格:¥电议型 号:T40915产 地:中国大陆
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T4084Sibofimloc;化合物Antibiotic-202VRT-1353385|||Antibiotic-202|||Antibiotic 202;VRT-1353385|||Antibiotic-2
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections.
价 格:¥电议型 号:T4084产 地:中国大陆
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T40808Glucocorticoids receptor agonist 1;Glucocorticoids receptor agonist 1Glucocorticoids receptor agonis
Glucocorticoids receptor agonist 1 (GRA-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. GRA-1 exhibits strong anti-inflammatory properties while maintaining insulin secretion function.
价 格:¥电议型 号:T40808产 地:中国大陆
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T407965β-Dihydrocortisone;5β-Dihydrocortisone5β-Dihydrocortisone
5β-Dihydrocortisone, a sterol metabolite derived from cortisone, is produced in the liver through the action of 5β-reductase (AKR1D1).
价 格:¥电议型 号:T40796产 地:中国大陆