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T71158Org 31806;化合物 Org 31806Org 31806
Org 31806 is a progestational hormone antagonist.
价 格:¥电议型 号:T71158产 地:中国大陆
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T71058Doramapimod HCl;化合物 Doramapimod HClDoramapimod HCl
Doramapimod HCl is the salt form of Doramapimod, a member of the N-pyrazole-N´-naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB -796 has entered clinical trials for the treatment of autoimmune diseases.
价 格:¥电议型 号:T71058产 地:中国大陆
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T7104Dovitinib lactate;多韦替尼乳酸盐CHIR-258 lactate|||TKI-258 lactate;CHIR-258 lactate|||多韦替尼乳酸盐|||TKI-258 lac
Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
价 格:¥电议型 号:T7104产 地:中国大陆
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T7103idalopirdine;化合物idalopirdineLu AE58054;Lu AE58054
Idalopirdine (Lu AE58054), a selective 5-HT6 receptor antagonist( Ki : 0.83 nM),as a treatment for Alzheimer´s disease.
价 格:¥电议型 号:T7103产 地:中国大陆
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T70958Dov-Val-Dil-OH TFA;化合物 Dov-Val-Dil-OH TFADov-Val-Dil-OH TFA
Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin.
价 格:¥电议型 号:T70958产 地:中国大陆
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T70928CB-1158-analog;化合物 CB-1158-analogCB-1158-analog
CB-1158-analog, also known as Numidargistat-analog and INCB01158-analog, is a potent and orally active arginase inhibitor with IC50=89 nM) . CB-1158 blocked myeloid cell-mediated suppression of T cell proliferation in vitro and reduced tumor growth in multiple mouse models of cancer, as a single agent and in combination with checkpoint blockade, adoptive T cell therapy, adoptive NK cell therapy, and the chemotherapy agent gemcitabine. CB-1158 increased tumor-infiltrating CD8+ T cells and NK cell
价 格:¥电议型 号:T70928产 地:中国大陆
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T70886PT-S58;化合物 PT-S58PT-S58
PT-S58 is a PPAR β/δ full antagonist, and a derivative of GSK0660. PT-S58 has a three-fold higher affinity for the receptor than GSK0660 and is a potent inhibitor of agonist-induced target gene expression. PT-S58 are effective on PPRE-independent functions of PPARβ/δ. Unlike GSK0660, PT-S58 blocks the recruitment co-repressor molecules such as SMRT.
价 格:¥电议型 号:T70886产 地:中国大陆
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T70858Nemiralisib succinate;化合物 Nemiralisib succinateNemiralisib succinate
Nemiralisib succinate is a potent and selective PI3Kδ inhibitor.
价 格:¥电议型 号:T70858产 地:中国大陆
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T70776AS-1669058 free base;化合物 AS-1669058 free baseAS-1669058 free base
AS-1669058 free base is a G-protein-coupled receptor 119 (GPR119) agonist used to as new drug to treat type 2 diabetes.
价 格:¥电议型 号:T70776产 地:中国大陆
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T70758Copanlisib HCl hydrate;化合物 Copanlisib HCl hydrateCopanlisib HCl hydrate
Copanlisib Dihydrochloride is a novel phosphoinositide 3-kinase (pi3k) inhibitor, inhibiting the activation of the pi3k signaling pathway, resulting in inhibition of tumor cell growth and survival in susceptible tumor cell populations
价 格:¥电议型 号:T70758产 地:中国大陆
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T70685CCG-203586;化合物 CCG-203586CCG-203586
CCG-203586 is a novel potent glucosylceramide synthase (GCS) inhibitor.
价 格:¥电议型 号:T70685产 地:中国大陆
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T70658Ici D8731;化合物 Ici D8731Ici D8731
Ici D8731 is a nonpeptide angiotensin II antagonist with potential as a treatment for hypertension and heart failure.
价 格:¥电议型 号:T70658产 地:中国大陆
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T70589Saprisartan potassium;化合物 Saprisartan potassiumSaprisartan potassium
Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.
价 格:¥电议型 号:T70589产 地:中国大陆
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T70588Tazemetostat HCl;化合物 Tazemetostat HClTazemetostat HCl
Tazemetostat HCl is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity. EPZ-6438 induces apoptosis and differentiation specifically in SMARCB1-deleted MRT cells. Treatment of xenograft-bearing mice with EPZ-6438 leads to dose-dependent regression of MRTs with correlative diminution of intratumoral trimethylation levels of lysine 27 on histone H3, and prevention of tumor regrowth after dosing cessation. These data demonstrate the dependency of SMARCB1
价 格:¥电议型 号:T70588产 地:中国大陆
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T70587CJ-12255;化合物 CJ-12255CJ-12255
CJ-12255 is a Neurokinin-1 Receptor Antagonist.
价 格:¥电议型 号:T70587产 地:中国大陆
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T70586S 2720;化合物 S 2720S 2720
S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline.
价 格:¥电议型 号:T70586产 地:中国大陆
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T70585Cyclazosin HCl;化合物 Cyclazosin HClCyclazosin HCl
Cyclazosin HCl is a hydrochloride composed of equimolar amounts of cyclazosin and hydrogen chloride. It has a role as an alpha1B-adrenoceptor antagonist. It contains a cyclazosin.
价 格:¥电议型 号:T70585产 地:中国大陆
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T70584FLA-99;化合物 FLA-99FLA-99
FLA-99 inhibits breakdown of inositol-1,4,5-triphosphate by inositol-1,4,5-triphosphate 5-phosphatase.
价 格:¥电议型 号:T70584产 地:中国大陆
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T70583Pemetrexed Diethyl Ester;化合物 Pemetrexed Diethyl EsterPemetrexed Diethyl Ester
Pemetrexed Diethyl Ester is a protected intermediate in the synthesis of Pemetrexed, a multi-targeted anti-folate that inhibits thymidylate synthase as well as other folate dependent enzymes.
价 格:¥电议型 号:T70583产 地:中国大陆
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T70581CY208-243 Mandelate;化合物 CY208-243 MandelateCY208-243 Mandelate
CY208-243 is a D1 agonist. CY208-243 attenuates the pattern electroretinogram to low spatial frequency stimuli in the monkey. CY208-243 stimulates adenylate cyclase in rat striatal homogenates with an EC50 of 125 nM. CY208,243 was superior in improving the strength of neuronal outcome sensitivity to the working memory-related choice behavior in the T-maze.
价 格:¥电议型 号:T70581产 地:中国大陆