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  • T60969Myt1-IN-1；化合物 Myt1-IN-1Myt1-IN-1

    Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].

    价 格：￥电议型 号：T60969产 地：中国大陆

  • T60962SARS-CoV-2-IN-18；化合物 SARS-CoV-2-IN-18SARS-CoV-2-IN-18

    SARS-CoV-2-IN-18 (Compound 26) is a potent inhibitor of SARS-CoV-2 3C-like protease (IC50 = 45 nM) [1].

    价 格：￥电议型 号：T60962产 地：中国大陆

  • T60961LANA-DNA-IN-1；化合物 LANA-DNA-IN-1LANA-DNA-IN-1

    LANA-DNA-IN-1 is a potent inhibitor of LANA-DNA with IC50 values of 8 μM, 9μM, and 8μM for LBS2, LBS1 and LBS3, respectively. The IC50 value of LANA-DNA-IN-1 against wild-type LANA is 53 μM. LANA-DNA-IN-1 can be used in the infection research [1].

    价 格：￥电议型 号：T60961产 地：中国大陆

  • T60947HDAC1/MAO-B-IN-1；化合物 HDAC1/MAO-B-IN-1HDAC1/MAO-B-IN-1

    HDAC1/MAO-B-IN-1 has the potential to be used in the Alzheimer’s disease research. HDAC1/MAO-B-IN-1 is a potent and selective inhibitor of HDAC1/MAO-B that can cross the blood-brain barrier. The IC50 values of HDAC1/MAO-B-IN-1 for HDAC1 and MAO-B are 21.4 nM and 99.0 nM, respectively [1].

    价 格：￥电议型 号：T60947产 地：中国大陆

  • T60946SLK/STK10-IN-1；化合物 SLK/STK10-IN-1SLK/STK10-IN-1

    SLK/STK10-IN-1 is a potent and selective SLK and STK10 inhibitor with nanomolar effect.

    价 格：￥电议型 号：T60946产 地：中国大陆

  • T60941LSD1-IN-15；化合物 LSD1-IN-15LSD1-IN-15

    LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor that inhibit LSD1-CoREST, MAO-A and MAO-B with IC 50 values of 0.149, 0.028, and 0.327 μM, respectively. LSD1-IN-15 shows cell growth arrest in LNCaP cells of prostate cancer. The IC50 value is 9.9 μM [1].

    价 格：￥电议型 号：T60941产 地：中国大陆

  • T60940ChE/Aβ1-42-IN-1；化合物 ChE/Aβ1-42-IN-1ChE/Aβ1-42-IN-1

    ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability. The IC50 values of ChE/Aβ1-42-IN-1 for AChE, BuChE and Aβ 1-42 aggregation are 0.062, 0.767 and 1.227 μM, respectively. ChE/Aβ1-42-IN-1 is a potent multi-targeted anti-Alzheimer´s disease agent [1].

    价 格：￥电议型 号：T60940产 地：中国大陆

  • T60930CAXII-IN-1；化合物 CAXII-IN-1CAXII-IN-1

    CAXII-IN-1 (Compound 17) has antitumor activity that is a selective inhibitor of CA XII. The Ki values of CAXII-IN-1 for hCA XII and hCA IX is 3.8 nM and 56.0 nM, respectively [1].

    价 格：￥电议型 号：T60930产 地：中国大陆

  • T60922RSK-IN-1；化合物 RSK-IN-1RSK-IN-1

    RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].

    价 格：￥电议型 号：T60922产 地：中国大陆

  • T60919SARS-CoV-2-IN-13；化合物SARS-CoV-2-IN-13SARS-CoV-2-IN-13

    SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide. SARS-CoV-2-IN-13 is more stable than niclosamide in human plasma and liver S9 enzymes assay. SARS-CoV-2-IN-13 can improve bioavailability and half-life when administered orally. SARS-CoV-2-IN-13 is a potent SARS-CoV-2 inhibitor with an IC 50 of 0.057 μM [1].

    价 格：￥电议型 号：T60919产 地：中国大陆

  • T60899IRAK4-IN-11；化合物 IRAK4-IN-11IRAK4-IN-11

    IRAK4-IN-11 (compound 6) is a potent inhibitor of IRAK4 with an IC 50 of 0.008 μM. IRAK4-IN-11 exhibits cell pIRAK4 potencies with an IC 50 of 0.19 μM [1].

    价 格：￥电议型 号：T60899产 地：中国大陆

  • T60896HER2-IN-11；化合物 HER2-IN-11HER2-IN-11

    HER2-IN-11 is a psoralen derivative that induces apoptosis. HER2-IN-11 shows light-activated cytotoxicity and also exhibits anti-breast cancer activity [1].

    价 格：￥电议型 号：T60896产 地：中国大陆

  • T60891AChE/BChE/MAO-B-IN-1；化合物AChE/BChE/MAO-B-IN-1AChE/BChE/MAO-B-IN-1

    AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1 μM, respectively. 1 had a neuroprotective effect and was not significantly cytotoxic.

    价 格：￥电议型 号：T60891产 地：中国大陆

  • T60890Xanthine oxidoreductase-IN-1；化合物 Xanthine oxidoreductase-IN-1Xanthine oxidoreductase-IN-1

    Xanthine oxidoreductase-IN-1 is a xanthine oxidoreductase (XOR) inhibitor with an IC 50 value of 7.0 nM.

    价 格：￥电议型 号：T60890产 地：中国大陆

  • T60885MLKL-IN-1；化合物 MLKL-IN-1MLKL-IN-1

    MLKL-IN-1 is a covalent inhibitor of MLKL with a Kd value of 50 μM.

    价 格：￥电议型 号：T60885产 地：中国大陆

  • T60877Mtb ATP synthase-IN-1；化合物 Mtb ATP synthase-IN-1Mtb ATP synthase-IN-1

    Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability. Mtb ATP synthase-IN-1 (compound 6ab) is a potent inhibitor of Mycobacterium tuberculosis (Mtb) ATP synthase (MIC = 0.452-0.499 μg/mL) [1].

    价 格：￥电议型 号：T60877产 地：中国大陆

  • T60871gp120-IN-1；化合物 gp120-IN-1gp120-IN-1

    gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an CC 50 of 100.90 μM and IC 50 of 2.2 μM. gp120-IN-1 inhibitis gp120-mediated virus enter into cells. gp120-IN-1 has anti-HIV-1 activity. gp120-IN-1 has dose-dependent cytotoxicity in SUP-T1 cells [1].

    价 格：￥电议型 号：T60871产 地：中国大陆

  • T60870BRG1-IN-1；化合物 BRG1-IN-1BRG1-IN-1

    BRG1-IN-1 (Compound 11d) is a potent BRG1 inhibitor with better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhibitor effect of Temozolomide on the subcutaneous GBM tumors growth[1].

    价 格：￥电议型 号：T60870产 地：中国大陆

  • T60862RIPK1-IN-15；化合物 RIPK1-IN-15RIPK1-IN-15

    RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].

    价 格：￥电议型 号：T60862产 地：中国大陆

  • T60861SARS-CoV-2 nsp3-IN-1；化合物 SARS-CoV-2 nsp3-IN-1SARS-CoV-2 nsp3-IN-1

    SARS-CoV-2 nsp3-IN-1 (Compound 15c) shows significant selectivity for coronavirus macrodomains, especially SARS-CoV-2 Mac1. SARS-CoV-2 nsp3-IN-1 can inhibit Mac1 ADP-ribosylhydrolase activity that is an inhibitor of Mac1 (IC50 = 6.1 μM) [1].

    价 格：￥电议型 号：T60861产 地：中国大陆

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