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T2310LCHIR-99021 HCl；CHIR-99021盐酸盐CT99021 HCl|||Laduviglusib HCl；CT99021 HCl|||Laduviglusib HCl
CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3α/β, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivity over CDC2, ERK2, and other protein kinases. Additionally, CHIR-99021 HCl serves as a robust activator of the Wnt/β-catenin signaling pathway. Moreover, it exhibits the ability to enhance self-renewal in both mouse and human embryonic stem cells. Furthermore, CHIR-99021 HCl indu
价 格：￥电议型 号：T2310L产 地：中国大陆
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T23028MRT67307 HCl (1190378-57-4 free base)；化合物 T23028MRT67307 HCl；MRT67307 HCl
MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it is a salt inducible kinase (SIK) inhibitor with IC50 value of 250, 67 and 430nM for SIK1, SIK2 and SIK3, respectively.
SIKs prevent the formation of regulatory macrophages and their inhibition induces increasing in some markers of regulatory macrophages, such as IL-10 and oth价 格：￥电议型 号：T23028产 地：中国大陆
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T22957LY2606368 HCl (1234015-52-1 free base)；化合物 T22957LY2606368 HCl；LY2606368 HCl
LY2606368 HCl is a selective ATP competitive inhibitor of checkpoint kinase 1 (IC50: 1.5nM in SW1990 cells).
价 格：￥电议型 号：T22957产 地：中国大陆
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T22936Idalopirdine Hydrochloride；Lu AE58054盐酸盐Lu AE58054 Hydrochloride|||Idalopirdine HCl；Lu AE58054盐酸盐|||
Idalopirdine Hydrochloride (Lu AE58054 Hydrochloride) is an in-vivo binding affinity and effect, in-vitro selectivity and potency of 5-HT(6)R antagonist (Ki: 0.83 nM).
价 格：￥电议型 号：T22936产 地：中国大陆
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T2287PIK-75 hydrochloride化合物PIK-75 hydrochloridePIK-75 HCl|||2-甲基-5-硝基苯磺酸 [(6-溴咪唑并[1,2-a]吡啶-3-基)亚甲基]甲基肼盐
PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
价 格：￥电议型 号：T2287产 地：中国大陆
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T22820GSK J5 HCl (1394854-51-3 free base)；化合物 T22820GSK J5 HCl；GSK J5 HCl
GSK J5 HCl is the hydrochloride form of GSK J5. GSK J5 is an inactive isomer of GSK J4 and a cell-permeable ester derivative of inactive control GSK J2.
价 格：￥电议型 号：T22820产 地：中国大陆
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T22817GSK 789472 hydrochloride；GSK 789472盐酸盐GSK-789472 HCl|||1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin
GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.
价 格：￥电议型 号：T22817产 地：中国大陆
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T22776Ezatiostat hydrochloride；Ezatiostat盐酸盐TLK199 HCl|||TER199；TLK199 HCl|||Ezatiostat盐酸盐|||TER199
Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydrochloride has been revealed to selectively bind to and thus inhibit GSTP1-1.
价 格：￥电议型 号：T22776产 地：中国大陆
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T22680CP-100356 hydrochloride；CP-100356 盐酸盐CP-100356 HCl|||CP 100356 hydrochloride；CP-100356 HCl|||CP 1003
CP-100356 hydrochloride is an orally active and low micromolar dual inhibitor of MDR1 (P-gp) and BCRP, a nucleotide-derived substrate analogue with inhibitory effects on MDR1-mediated Calcein-AM transporter and BCRP-mediated Prazosin transporter.CP-100356 Inhibits OATP1B1, induces stomatal opening in the dark.
价 格：￥电议型 号：T22680产 地：中国大陆
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T22638CBiPES hydrochloride；CBiPES盐酸盐CBiPES HCl；CBiPES HCl
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used to study neurological disorders like epilepsy and Parkinson´s syndrome. CBiPES hydrochloride can be used to study neurological disorders like epilepsy and Parkinson´s syndrome.
价 格：￥电议型 号：T22638产 地：中国大陆
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T2255SB-743921 hydrochloride；化合物SB743921SB743921 HCl|||SB743921；SB743921 HCl|||SB743921
SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).
价 格：￥电议型 号：T2255产 地：中国大陆
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T22451UK-371804 HCl化合物UK-371804 HClUK 371804 HCl|||UK371804 HCl
UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-fold versus plasmin and 4000-fold versus tPA).
价 格：￥电议型 号：T22451产 地：中国大陆
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T22435Tacrine hydrochloride；盐酸他克林Tacrine HCl；四氢氨基吖啶|||盐酸他克林|||Tacrine HCl
Tacrine is a indirect cholinergic agonist and centrally acting anticholinesterase. Tacrine hydrochloride hydrate is an inhibitor of acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.
价 格：￥电议型 号：T22435产 地：中国大陆
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T22420(S)-Viloxazine Hydrochloride；化合物(S)-Viloxazine盐酸盐(S)-Viloxazine HCl；(S)-Viloxazine HCl
(S)-Viloxazine Hydrochloride, the S-isomer of Viloxazine. Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant.
价 格：￥电议型 号：T22420产 地：中国大陆
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T22401PNU-282987 S enantiomer hydrochloride；化合物PNU-282987 S enantiomer hydrochloride(S)-PNU-282987 HCl；(S)
(S)-PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987, a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor, has negligible activity against α1β1γδ and α3β4 nAChRs as well as a panel of monoamine, glutamate, muscarinic,and GABA receptors, except 5-HT3 with Ki of 930 nM.
价 格：￥电议型 号：T22401产 地：中国大陆
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T22390Olanexidine Hydrochloride semihydrate；奥兰西丁标准品HCLOPB-2045|||OPB-2045G；OPB-2045|||OPB-2045G|||奥兰西丁标准品H
Olanexidine is a monobiguanide compound with the activity of bactericidal.
价 格：￥电议型 号：T22390产 地：中国大陆
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T22378Nilotinib hydrochloride；尼罗替尼盐酸盐AMN-107 HCl；AMN-107 HCl
Nilotinib hydrochloride(AMN-107 HCl) is an orally available Bcr-Abl tyrosine kinase inhibitor with antitumor activity for modulation of neuroinflammation and cognitive deficits, and may be used in studies of chronic myelogenous leukemia.
价 格：￥电议型 号：T22378产 地：中国大陆
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T22364Methyl 4-aminobutyrate HCl；4-氨基丁酸甲酯盐酸盐Methyl 4-aminobutyrate hydrochloride|||GABA methyl ester；4-氨基丁
Methyl 4-aminobutyrate HCl (GABA methyl ester) is a methyl ester compound derived from the condensation of aminobutyric acid and methanol.
价 格：￥电议型 号：T22364产 地：中国大陆
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T22342GSK3368715 3HCl；化合物GSK3368715 (EPZ019997) 3HClEPZ019997 3HCl|||GSK3368715(EPZ019997)；EPZ019997 3HCl|
GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM.
价 格：￥电议型 号：T22342产 地：中国大陆
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T22325EPZ020411 hydrochloride；化合物EPZ020411 HClEPZ020411 HCl；EPZ020411 HCl
EPZ020411 hydrochloride is a selective and potent small molecule PRMT6 inhibitor with an IC50 value of 10 nM.
价 格：￥电议型 号：T22325产 地：中国大陆
