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T12785RXFP3/4 agonist 1;化合物 T12785RXFP3/4 agonist 1
RXFP3/4 agonist 1 is a relaxin family peptide 3/4 receptor (RXFP3/4) agonist(EC50s of 82/2 nM, respectivley).
价 格:¥电议型 号:T12785产 地:中国大陆
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T12778RTI-13951-33 hydrochloride;化合物 T12778RTI-13951-33 hydrochloride (2244884-08-8 free base);RTI-13951-3
RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist. RTI-13951-33 hydrochloride exhibited an EC 50 of 25 nM in vitro cAMP functional assay. RTI-13951-33 hydrochloride significantly reduces alcohol reinforcement and intake behaviors in rats [1].
价 格:¥电议型 号:T12778产 地:中国大陆
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T12765RPR107393 free base;化合物 T12765RPR107393 free base
RPR107393 free base is a selective inhibitor of squalene synthase(rat liver microsomal squalene synthase, with an IC50 of 0.8 nM).
价 格:¥电议型 号:T12765产 地:中国大陆
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T1276Danofloxacin mesylate;甲磺酸达氟沙星CP 76136-27;甲磺酸达氟沙星|||CP 76136-27
Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase.
价 格:¥电议型 号:T1276产 地:中国大陆
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T1275Phentolamine mesylate;甲磺酸酚妥拉明Phentolamine methanesulfonate|||Phentolamine mesilate;Phentolamine meth
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
价 格:¥电议型 号:T1275产 地:中国大陆
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T12749Roflumilast Impurity E;罗氟司特杂质ERoflumilast Impurity E
Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast acts as a selective and long-acting the enzyme PDE-4 inhibitor(IC50 value of 0.8 nM).
价 格:¥电议型 号:T12749产 地:中国大陆
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T12738L1Rivanicline 2HCl;(E)-位变异烟碱盐酸盐Rivanicline 2HCl(15585-43-0 Free base);Rivanicline 2HCl(15585-43-0 Free
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.
价 格:¥电议型 号:T12738L1产 地:中国大陆
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T12737Riviciclib;化合物 T12737P276-00 (free base);P276-00 (free base)
Riviciclib is a potent inhibitor of cyclin-dependent kinase (CDK)(CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively),with antitumor activity on cisplatin-resistant cells.
价 格:¥电议型 号:T12737产 地:中国大陆
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T12732LRezafungin acetate;化合物 T12732LBiafungin acetate|||SP-3025 acetate|||CD101 acetate;Biafungin acetate|
Rezafungin acetate is an advanced echinocandin compound that exhibits broad-spectrum antifungal activity against Candida spp, Aspergillus spp, and Pneumocystis spp. This long-lasting next-generation medication showcases potent efficacy in combating fungal infections.
价 格:¥电议型 号:T12732L产 地:中国大陆
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T12732Rezafungin;棘白菌素SP-3025|||CD101|||Biafungin;棘白菌素|||SP-3025|||CD101|||Biafungin
Rezafungin (SP-3025) is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.
价 格:¥电议型 号:T12732产 地:中国大陆
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T1273Diacerein;双醋瑞因Diacerhein|||Fisiodar|||Diacetylrhein;双醋瑞因|||Diacerhein|||Fisiodar|||Diacetylrhein
Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre diarrhea [L780]. Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications.
价 格:¥电议型 号:T1273产 地:中国大陆
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T1272Cytarabine;阿糖胞苷Ara-C|||Cytosine Arabinoside|||Cytosine β-D-arabinofuranoside|||Arabinocytidine;阿糖胞苷|
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
价 格:¥电议型 号:T1272产 地:中国大陆
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T12718RG7800 hydrochloride (1449598-06-4 free base);化合物 T12718RO6885247 hydrochloride|||RG7800 hydrochlori
RG7800 hydrochloride is an orally active modulator of SMN2 splicing.
价 格:¥电议型 号:T12718产 地:中国大陆
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T1270Vincristine sulfate;硫酸长春新碱Leurocristine|||22-Oxovincaleukoblastine sulfate|||Leurocristine sulfate;L
Vincristine sulfate (Leurocristine sulfate) binds irreversibly to microtubules and spindle proteins in S phase and interferes the formation of the mitotic spindle.
价 格:¥电议型 号:T1270产 地:中国大陆
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T12698Regorafenib-d3;化合物 T12698Regorafenib D3|||BAY 73-4506 D3;Regorafenib D3|||BAY 73-4506 D3
Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.
价 格:¥电议型 号:T12698产 地:中国大陆
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T12697Refametinib R enantiomer;Refametinib (R对映体)RDEA119 R enantiomer|||Refametinib R enantiomer|||BAY 869
Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research.
价 格:¥电议型 号:T12697产 地:中国大陆
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T12685RAF mutant-IN-1;化合物 T12685RAF mutant-IN-1
RAF mutant-IN-1 is an inhibitor of RAF kinase(IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively).
价 格:¥电议型 号:T12685产 地:中国大陆
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T12684Radioprotectin-1;化合物Radioprotectin-15-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
价 格:¥电议型 号:T12684产 地:中国大陆
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T12680(±)-Darifenacin;化合物 T12680(±)-UK-88525;(±)-UK-88525
(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.
价 格:¥电议型 号:T12680产 地:中国大陆
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T12673LPF-06250112;化合物 T12673LPF-06250112
PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively).
价 格:¥电议型 号:T12673L产 地:中国大陆