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T28160Nerispirdine HCl;化合物 T28160HP-184|||HP 184|||Nerispirdine hydrochloride|||HP184;HP-184|||HP 184|||Ne
Nerispirdine is a acetylcholine release enhancer, sodium channel blocker and K(V) 2.1 channel blocker. Nerispirdine inhibits voltage-dependent Na(+) channel currents recorded from human SH-SY5Y cells with an IC(50) of 11.9 micromol/L when measured from a -70 mV holding potential. Nerispirdine also inhibits K(v)1.1 and K(v)1.2 with IC(50) values of 3.6 and 3.7 micromol/L, respectively.
价 格:¥电议型 号:T28160产 地:中国大陆
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T28145ND-322 HCl;化合物ND-322 HClND 322 Hydrochloride|||ND322 Hydrochloride|||ND-322 Hydrochloride|||ND322 HC
ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.
价 格:¥电议型 号:T28145产 地:中国大陆
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T28107MRT-68601 HCl;化合物 T28107MRT-68601 HCl
MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.
价 格:¥电议型 号:T28107产 地:中国大陆
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T2806LLappaconitine HCl;化合物 T2806LLappaconitine hydrochloride;Lappaconitine hydrochloride
Lappaconitine HCl is a centrally acting non-opioid analgesic and class-I antiarrhythmic. It acts by binding to the site-2 receptor and irreversibly blocking hH1 sodium channels.
价 格:¥电议型 号:T2806L产 地:中国大陆
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T28038Milademetan HCl (1398568-47-2 free base);化合物 T28038Milademetan HCl|||DS3032|||DS 3032|||DS-3032|||DS
Milademetan is a potent and selective MDM2 inhibitor. MDM2 inhibitor DS-3032b binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53 upon oral administration. By preventing this MDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited and the transcriptional activity of p53 is restored. This results in the restoration of p53 signaling and leads to the p53-mediated induction of tumor cell apopto
价 格:¥电议型 号:T28038产 地:中国大陆
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T28030Metralindole HCl;化合物 T28030Inkazan|||Metralindole|||Incasan;Inkazan|||Metralindole|||Incasan
Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.
价 格:¥电议型 号:T28030产 地:中国大陆
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T27947LLY339434 HCl;化合物LY339434盐酸盐LY339434 HCl(219566-62-8 Free base);LY339434 HCl(219566-62-8 Free base)
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA) receptors.
价 格:¥电议型 号:T27947L产 地:中国大陆
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T27891LY195448 HCl;化合物 LY195448 HClLY195448|||UNII-BR0DFE3GF6|||LY-195448;LY195448|||UNII-BR0DFE3GF6|||LY-
LY195448 HCl is a phenethanolamine shown anti-tumour activity. It blocks cells at metaphase.
价 格:¥电议型 号:T27891产 地:中国大陆
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T27859LTX-401 HCl;化合物 T27859LTX 401|||LTX401|||LTX-401;LTX 401|||LTX401|||LTX-401
LTX-401 is an immunotherapeutic agent and an oncolytic amino acid derivative with potential immunogenic properties.
价 格:¥电议型 号:T27859产 地:中国大陆
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T27846Lotrafiban hydrochloride;化合物 T27846SB 214857a|||Lotrafiban HCl|||SB-214857-A;SB 214857a|||Lotrafiban
Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.
价 格:¥电议型 号:T27846产 地:中国大陆
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T27843Lometraline hydrochloride;化合物 T27843CP-14,368-1|||UNII-T2OJ193WGR|||Lometraline HCl|||CP 14,368-1;CP
Lometraline hydrochloride is a drug which is an aminotetralin derivative with the potential activity of antidepressant and/or anxiolytic.
价 格:¥电议型 号:T27843产 地:中国大陆
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T27820Levoprotiline hydrochloride;化合物 T27820CGP 12103 A|||CGP-12 103 A|||Levoprotiline HCl;CGP 12103 A|||C
Levoprotiline hydrochloride is an antidepressant.
价 格:¥电议型 号:T27820产 地:中国大陆
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T27806Lecozotan HCl;盐酸来考佐坦SRA-333|||SRA333|||SRA 333|||Lecozotan hydrochloride;SRA-333|||SRA333|||SRA 333|
Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. Chronic administration of Lecozotan HCl did not induce 5-HT(1A) receptor tolerance or desensitization in a behavioral model demonstrating 5-HT(1A) receptor function.
价 格:¥电议型 号:T27806产 地:中国大陆
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T27773LL-739750 2HCl;L-739750盐酸盐L-739750 2HCl(160141-08-2 Free base);L-739750 2HCl(160141-08-2 Free base)
L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.
价 格:¥电议型 号:T27773L产 地:中国大陆
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T27723LKDM5-C49 HCl;KDM5-C49醋酸盐KDM5-C49 HCl(1596348-16-1 Free base)|||KDOAM-20 hydrochloride;KDM5-C49 H
KDM5-C49 HCl (KDOAM-20 hydrochloride) is a potent and selective inhibitor of KDM5 demethylase. KDM5-C49 HCL(1596348-16-1 Free base) is a candidate compound for the treatment of cancer.
价 格:¥电议型 号:T27723L产 地:中国大陆
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T27699JTZ-951 HCl;化合物 T27699JTZ-951 Hydrochloride|||JTZ951 HCl|||JTZ 951 Hydrochloride|||JTZ-951|||JTZ 951
JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).
价 格:¥电议型 号:T27699产 地:中国大陆
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T27695JTE-607;甲氧番荔枝碱JTE-607 dihydrochloride|||JTE-607 HCl;JTE-607 dihydrochloride|||JTE-607 HCl|||甲氧番荔枝碱
JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.
价 格:¥电议型 号:T27695产 地:中国大陆
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T27689JNJ-7925476 HCl;化合物 T27689JNJ-7925476|||JNJ7925476|||JNJ 7925476;JNJ-7925476|||JNJ7925476|||JNJ 7925
JNJ-7925476 HCl is a triple monoamine uptake inhibitor. JNJ-7925476 Salt blocks the dopamine transporter (DAT), norepinephrine transporter (NET) and serotonin transporter (SERT) in the central nervous system. The ED(50) values for JNJ-7925476 occupancy of the DAT, NET and SERT in rat brain were 2.4, 0.09, 0.18 and mg/kg, respectively.
价 格:¥电议型 号:T27689产 地:中国大陆
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T2764(S)-10-Hydroxycamptothecin;10-羟基喜树碱10-Hydroxycamptothecin|||10-HCPT;10-羟喜树碱|||10-羟基喜树碱|||10-Hydroxyc
(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
价 格:¥电议型 号:T2764产 地:中国大陆
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T27637ISQ-1 HCl;化合物 T27637ISQ-1|||ISQ1|||ISQ 1;ISQ-1|||ISQ1|||ISQ 1
ISQ-1 HCl is an isoquinolinone (IKur) blocker with possible atrial arrhythmia activity.
价 格:¥电议型 号:T27637产 地:中国大陆