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T60572HER2-IN-10;化合物 HER2-IN-10HER2-IN-10
HER2-IN-10 is a psoralen derivative that induces apoptosis. HER2-IN-10 shows anti-breast cancer activity and light-activated cytotoxicity [1].
价 格:¥电议型 号:T60572产 地:中国大陆
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T60571O-GlcNAcase-IN-1;化合物 O-GlcNAcase-IN-1O-GlcNAcase-IN-1
O-GlcNAcase-IN-1 is a potent and novel inhibitor of O-GlcNAcase(OGA) with an IC 50 value of 46 nM.
价 格:¥电议型 号:T60571产 地:中国大陆
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T60566COX-2-IN-12;化合物 COX-2-IN-12COX-2-IN-12
COX-2-IN-12 (compound 3b) is a potent and selective COX-2 inhibitor with an IC 50 of 19.98 μM. COX-2-IN-12 is an anti-inflammatory agent that shows safety in-vivo acute toxicity studies [1].
价 格:¥电议型 号:T60566产 地:中国大陆
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T60563NLRP3/AIM2-IN-1;化合物 NLRP3/AIM2-IN-1NLRP3/AIM2-IN-1
NLRP3/AIM2-IN-1 is an inhibitor of thermal sepsis (IC50 = 3.136 ± 0.7667 μM).
价 格:¥电议型 号:T60563产 地:中国大陆
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T60557TRAP-6-IN-1;化合物 TRAP-6-IN-1TRAP-6-IN-1
TRAP-6-IN-1 (Compound 8) is a dual inhibitor of collagen and TRAP-6 with IC 50 values of 17.12 μM and 11.88 μM, respectively. TRAP-6-IN-1 non-competitively inhibits agonist-induced platelet aggregation[1].
价 格:¥电议型 号:T60557产 地:中国大陆
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T60556SARS-CoV-2-IN-16;化合物 SARS-CoV-2-IN-16SARS-CoV-2-IN-16
SARS-CoV-2-IN-16 (Compound 12) is a potent inhibitor of SARS-CoV-2 nucleocapsid protein (NPro) with potent antiviral activity (EC50 = 3.69 μM). SARS-CoV-2-IN-16 binds to NPro with a low Kd value of 7.82 μM, which suggests that SARS-CoV-2-IN-16 is an effective NPro ligand [1].
价 格:¥电议型 号:T60556产 地:中国大陆
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T60550ALDH1A3-IN-1;化合物 ALDH1A3-IN-1ALDH1A3-IN-1
ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].
价 格:¥电议型 号:T60550产 地:中国大陆
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T60544HPV18-IN-1;化合物 HPV18-IN-1HPV18-IN-1
HPV18-IN-1 (Compound H1) is a potent HPV18 inhibitor that prevents cervical cancer cells from premature cell procession and abnormal proliferation. HPV18-IN-1 supresses E7-Rb-E2F cellular pathway and DNA methylation with the potential for cancer research.
价 格:¥电议型 号:T60544产 地:中国大陆
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T60542BTK-IN-16;BTK抑制剂16BTK-IN-16
BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.
价 格:¥电议型 号:T60542产 地:中国大陆
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T60534JNK-IN-11;JNK 抑制剂 11JNK-IN-11
JNK-IN-11 is a potent JNK inhibitor that inhibits JNK1, JNK2, and JNK3 with IC50 values of 1.8, 21.4, and 2.2 ?M, respectively.JNK-IN-11 can be used to study abnormalities in immune function.
价 格:¥电议型 号:T60534产 地:中国大陆
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T60515CaMKIIα-IN-1;化合物 CaMKIIα-IN-1CaMKIIα-IN-1
CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub. CaMKIIα-IN-1 shows good metabolic stability [1].
价 格:¥电议型 号:T60515产 地:中国大陆
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T60495PARP10/15-IN-1;化合物 PARP10/15-IN-1PARP10/15-IN-1
PARP10/15-IN-1 (compound 8l) is a dual PARP10 and PARP15 inhibitor with IC50s of 160 nM and 370 nM, respectively. It can be used in cancer research[1].
价 格:¥电议型 号:T60495产 地:中国大陆
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T60491Elongation factor P-IN-1;化合物 Elongation factor P-IN-1Elongation factor P-IN-1
Elongation factor P-IN-1 is a potent elongation factor P (EFP) inhibitor that is a β-lysine derivative compound. Elongation factor P-IN-1 affects E. coli proliferation rate[1].
价 格:¥电议型 号:T60491产 地:中国大陆
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T60489hMAO-B/MB-COMT-IN-1;化合物 hMAO-B/MB-COMT-IN-1hMAO-B/MB-COMT-IN-1
hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor with IC50s of 2.5 μΜ for hMAO-B and 3.84 μΜ for MB-COMT. hMAO-B/MB-COMT-IN-1 protects cells from oxidative damage that can be used in neurodegeneration disease research, for example, Parkinson’s Disease (PD) [1].
价 格:¥电议型 号:T60489产 地:中国大陆
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T60486Mycobactin-IN-1;化合物 Mycobactin-IN-1Mycobactin-IN-1
Mycobactin-IN-1 (compound 44) is a pyrazoline analogue. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA) which is a key enzyme in the mycobactin biosynthetic pathway. Mycobactin-IN-1 is an inhibitor of mycobactin biosynthesis that against mycobacteria [1].
价 格:¥电议型 号:T60486产 地:中国大陆
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T60477Haspin-IN-1;化合物 Haspin-IN-1Haspin-IN-1
Haspin-IN-1 (compound 2a) is an inhibitor of haspin (haploid germ cell-specific nuclear protein kinase) with an IC50 of 119 nM. Haspin-IN-1 also inhibits CLK1, DYRK1A, and CDK9 with IC50 of 221 nM, 916.3 nM, and 406.8 nM, respectively. Haspin-IN-1 has the potential for the development of new anticancer drugs [1].
价 格:¥电议型 号:T60477产 地:中国大陆
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T60457COX-2-IN-11;化合物 COX-2-IN-11COX-2-IN-11
COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].
价 格:¥电议型 号:T60457产 地:中国大陆
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T60450AChE/hCA I/II-IN-1;化合物 AChE/hCA I/II-IN-1AChE/hCA I/II-IN-1
AChE/hCA I/II-IN-1 (Compound 6) is a potent AChE/Hca inhibitor with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca Ⅰ and Hca Ⅱ. AChE/hCA I/II-IN-1 can be used in glaucoma, Alzheimer´s disease, and diabetes rsearch[1].
价 格:¥电议型 号:T60450产 地:中国大陆
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T60449Tyrosinase-IN-1;化合物 Tyrosinase-IN-1Tyrosinase-IN-1
Tyrosinase-IN-1 (compound 90) is a potent tyrosinase inhibitor. As a promising target, tyrosinase inhibitors can be used as skin-whitening agents and food preservatives, thus having broad potential in the fields of food, cosmetics, agriculture and medicine. [1].
价 格:¥电议型 号:T60449产 地:中国大陆
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T60427Cdc7-IN-15;化合物 Cdc7-IN-15Cdc7-IN-15
Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].
价 格:¥电议型 号:T60427产 地:中国大陆