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T11212EPAC 5376753;化合物EPAC 53767535-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimid
EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 ?M in Swiss 3T3 cells.
价 格:¥电议型 号:T11212产 地:中国大陆
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T11173LElacestrant S enantiomer dihydrochloride;化合物 T11173LRAD1901 S enantiomer dihydrochloride|||RAD-1901
Elacestrant (RAD1901) dihydrochloride is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant S enantiomer dihydrochloride is an low activity enantiomer of elacestrant dihydrochloride.
价 格:¥电议型 号:T11173L产 地:中国大陆
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T1110Meclizine dihydrochloride盐酸美克洛嗪Meclozine dihydrochloride|||NSC28728|||Meclizine 2HCl|||盐酸美克洛嗪
Meclizine dihydrochloride (NSC28728) is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.
价 格:¥电议型 号:T1110产 地:中国大陆
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T11095DREADD agonist 21 dihydrochloride;化合物 T11095DREADD agonist 21 dihydrochloride (56296-18-5 free base)
DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].
价 格:¥电议型 号:T11095产 地:中国大陆
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T11044Dihydromunduletone化合物DihydromunduletoneDHM
Dihydromunduletone (DHM) is an adhesion G protein-coupled receptor (aGPCR) antagonist that acts as a chemical probe for the inhibition of GPR56 and GPR114/ADGRG5, which have similar tethered agonists.
价 格:¥电议型 号:T11044产 地:中国大陆
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T11043Dihydroergocristine mesylate;甲磺酸双氢麦角汀DHEC (mesylate);甲磺酸双氢麦角汀|||DHEC (mesylate)
Dihydroergocristine mesylate (DHEC (mesylate))(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. Dihydroergocristine mesylate is a inhibitor of γ-secretase (GSI), , reduces the production of the Alzheimer´s disease amyloid-β peptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation con
价 格:¥电议型 号:T11043产 地:中国大陆
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T11042Dihydrocytochalasin B;二氢细胞松弛素 BDihydrocytochalasin B
Dihydrocytochalasin B (H2CB) is a cell division inhibitor that changes the morphology of cells, similar to cytochalasin B. Does not inhibit glucose transport. Dihydrocytochalasin B (H2CB) disrupts the structure of actin and inhibits the ability of growth factors to stimulate DNA synthesis, reversibly preventing the initiation of DNA synthesis. Dihydrorelaxin B (H2CB) inhibits active calcium transport and causes an increase in calcium ions in mucosal scrape.
价 格:¥电议型 号:T11042产 地:中国大陆
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T11041Dihydro-β-erythroidine hydrobromide;化合物 T11041DHβE hydrobromide;DHβE hydrobromide
Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs). Dihydro-β-carotene hydrobromide showed selectivity to α4β4 and α4β2nAChR, with IC50 of 0.19 and 0.37 μM, respectively.
价 格:¥电议型 号:T11041产 地:中国大陆
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T11040Dihydro Dutasteride;化合物 T11040Dihydro Dutasteride
Dihydro Dutasteride is a metabolite of Dutasteride. Dutasteride is an effective inhibitor of five α-reductase isozymes.
价 格:¥电议型 号:T11040产 地:中国大陆
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T11011Dexpramipexole dihydrochloride;右旋普拉克索二盐酸盐KNS-760704 dihydrochloride|||R-(+)-Pramipexole dihydrochlor
Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.
价 格:¥电议型 号:T11011产 地:中国大陆
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T10983LDDP-38003 dihydrochloride;DDP-38003盐酸盐DDP-38003 dihydrochloride
DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).
价 格:¥电议型 号:T10983L产 地:中国大陆
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T10964LDB1976 dihydrochloride;DB1976盐酸盐DB1976 hydrochloride|||DB1976 2HCl;DB1976 hydrochloride|||DB1976 2HC
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and improved glucose homeostasis and dyslipidemia in mice in in vivo experiments.DB1976 dihydrochloride promotes apoptosis and may be used in studies of metabolic dysfunction and non-alcoholic steatohepatitis.
价 格:¥电议型 号:T10964L产 地:中国大陆
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T10939D,L-Cystathionine dihydrochloride;化合物 T10939D,L-Cystathionine dihydrochloride
D,L-Cystathionine dihydrochloride is an intermediate in the synthesis of cysteine, which acts from the isotype of cysteine-β-synthase (CBS) produced by leucine and serine. Derived from cysteine. DL-cysteine contains a cysteine (βC-S) carbon-sulfur bond.
价 格:¥电议型 号:T10939产 地:中国大陆
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T10931d-Atabrine dihydrochloride;化合物 T10931d-Atabrine dihydrochloride
d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.
价 格:¥电议型 号:T10931产 地:中国大陆
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T10692CB-1158 dihydrochloride (2095732-06-0 free base);化合物 T10692INCB01158 dihydrochloride|||CB-1158 dihyd
CB-1158 dihydrochloride is an effective and orally active inhibitor of arginase (IC50s: 86 nM and 296 nM for recombinant human arginase 1 and 2).
价 格:¥电议型 号:T10692产 地:中国大陆
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T10639C-021 dihydrochloride;化合物C-021 dihydrochlorideC-021 dihydrochloride
C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.
价 格:¥电议型 号:T10639产 地:中国大陆
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T10568BMS-470539 dihydrochloride;化合物 T10568BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective agonist of the melanocortin-1 receptor (MC-1R; IC50: 120 nM; EC50: 28 nM) with anti-inflammatory properties. It does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R.
价 格:¥电议型 号:T10568产 地:中国大陆
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T10462LBavisant dihydrochloride hydrate;化合物 T10462LJNJ31001074AAC;JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格:¥电议型 号:T10462L产 地:中国大陆
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T10462Bavisant dihydrochloride;化合物 T10462Bavisant dihydrochloride
Bavisant (JNJ-310010740) dihydrochloride is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition.
价 格:¥电议型 号:T10462产 地:中国大陆
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T10459Banoxantrone dihydrochloride;巴诺蒽醌盐酸盐Banoxantrone|||Banoxantrone dihydrochloride|||Banoxantrone|||AQ4
Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.
价 格:¥电议型 号:T10459产 地:中国大陆