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T10533BI-2852BI-2852
BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. BI-2852 is leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
价 格:¥电议型 号:T10533产 地:美洲
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T10537BI-749327BI-749327
BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).
价 格:¥电议型 号:T10537产 地:美洲
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T1054TolbutamideTolbutamide,HLS 831,
Tolbutamide is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.
价 格:¥电议型 号:T1054产 地:美洲
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T10541Bicyclomycin benzoateBicyclomycin benzoate,FR2054,
Bicyclomycin benzoate, an antibiotic, exhibits activity against a broad spectrum of Gram-negative/Gram-positive bacteria.
价 格:¥电议型 号:T10541产 地:美洲
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T10543BIIL-260 hydrochlorideBIIL-260 hydrochloride
BIIL-260 hydrochloride is a potent and long-acting orally active antagonist of leukotriene B4 (LTB4) receptor with anti-inflammatory activity. It has a high affinity to the LTB4 receptor on isolated human neutrophil cell membranes (Ki: 1.7 nM).
价 格:¥电议型 号:T10543产 地:美洲
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T10548Biotin-VAD-FMKBiotin-VAD-FMK
Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled inhibitor of caspase. It is used to identify active caspases in cell lysates.
价 格:¥电议型 号:T10548产 地:美洲
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T1055IfosfamideIfosfamide,NSC109724,Isophosphamide
Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mustard cyclophosphamide with antineoplastic activity. This agent is a prodrug that must be activ
价 格:¥电议型 号:T1055产 地:美洲
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T10550Bisindolylmaleimide X hydrochlorideBisindolylmaleimide X hydrochloride,BIM-X hydrochloride,Ro31-8425
Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM).
价 格:¥电议型 号:T10550产 地:美洲
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T10551Bithionol sulfoxideBithionol sulfoxide
Bithionol sulfoxide is a clinically approved antiparasitic drug with the inhibitory against solid tumor growth in several preclinical cancer models.
价 格:¥电议型 号:T10551产 地:美洲
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T10552Bitopertin R enantiomerBitopertin R enantiomer,RG1678 (R enantiomer),RO4917838 (R enantiomer)
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM).
价 格:¥电议型 号:T10552产 地:美洲
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T10554BixinBixin
Bixin is isolated from the seeds of Bixa orellana and possesses anti-tumor, anti-inflammatory, and antioxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation, and ROS generation.
价 格:¥电议型 号:T10554产 地:美洲
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T10557BLM-IN-1BLM-IN-1
BLM-IN-1 is an effective Bloom syndrome protein (BLM) inhibitor (KD: 1.81 μM; IC50: 0.95 μM). It induces DNA damage response, apoptosis and proliferation arrest in cancer cells
价 格:¥电议型 号:T10557产 地:美洲
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T1056Isoprenaline hydrochlorideIsoprenaline hydrochloride,Isoproterenol hydrochloride,Isoprenaline HCl
Isoproterenol is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties.
价 格:¥电议型 号:T1056产 地:美洲
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T10564(8R,9S)-Talazoparib(8R,9S)-Talazoparib,(8R,9S)-BMN-673,
(8R,9S)-Talazoparib is Talazoparib enantiomer , less active than Talazoparib on the inhibition of PARP1 (IC50: 144 nM).
价 格:¥电议型 号:T10564产 地:美洲
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T10565BMS-1001 hydrochlorideBMS-1001 hydrochloride
BMS-1001 hydrochloride is an orally active inhibitor of human PD-L1/PD-1 immune checkpoint with low-toxicity in cells.
价 格:¥电议型 号:T10565产 地:美洲
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T10566BMS-191095BMS-191095
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
价 格:¥电议型 号:T10566产 地:美洲
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T10567BMS-214662BMS-214662
BMS-214662 is an effective and selective inhibitor of farnesyl transferase with potent antitumor activity (IC50: 1.35 nM).
价 格:¥电议型 号:T10567产 地:美洲
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T1057AzilsartanAzilsartan,TAK-536,
Azilsartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect of azilsartan is by means of Decreased Blood Pressure.
价 格:¥电议型 号:T1057产 地:美洲
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T10570Fostemsavir TrisFostemsavir Tris,BMS-663068 Tris,
Fostemsavir Tris is the prodrug of BMS-626529. Fostemsavir Tris is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
价 格:¥电议型 号:T10570产 地:美洲
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T10573BMT-145027BMT-145027
BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50: 47 nM).
价 格:¥电议型 号:T10573产 地:美洲