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TQ0059Ilorasertibanti-tumor,H1299,Platelet-derived growth factor receptor,Inhibitor,ABT 348,antiproliferat
Ilorasertib (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).
价 格：￥电议型 号：TQ0059产 地：中国大陆
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TP1263Fz7-21lipid-binding groove,FZD7,Wnt,Fz7 21,Wnt–β-catenin,Fz-7-21,conformation,FZD7 CRD,intestinal or
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
价 格：￥电议型 号：TP1263产 地：中国大陆
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T7812AcitazanolastAcitazanolast
Acitazanolast is an anti-allergic drug candidate.
价 格：￥电议型 号：T7812产 地：中国大陆
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TP1216CaM kinase II inhibitor TFA saltCaM kinase II inhibitor TFA salt
Autocamtide-2-Related Inhibitory Peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
价 格：￥电议型 号：TP1216产 地：中国大陆
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T7553(+)-PD 128907 hydrochloride(+)-PD 128907,Dopamine Receptor,inhibit,(+) PD 128907 hydrochloride,Inhib
(+)-PD 128907 hydrochloride is an agonist of D3 dopamine receptor .
价 格：￥电议型 号：T7553产 地：中国大陆
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T41275PF-04753299PF04753299,PF 04753299
PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC). PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC 90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection [1].
价 格：￥电议型 号：T41275产 地：中国大陆
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TN12623-Feruloylquinic acid3Feruloylquinic acid,3 Feruloylquinic acid
3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
价 格：￥电议型 号：TN1262产 地：中国大陆
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T10572BMT-124110BMT 124110,BMT124110
BMT-124110 is an effectivet, selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE; IC50: 17 nM) and Cyclin G-associated kinase (GAK; IC50: 99 nM).
价 格：￥电议型 号：T10572产 地：中国大陆
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T8512BAY-545Inhibitor,BAY 545,BAY545,Adenosine Receptor,BAY-545,P1 receptor,inhibit
BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).
价 格：￥电议型 号：T8512产 地：中国大陆
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T61233Penehyclidine hydrochloride
Penehyclidine hydrochloride is an?M1?and?M3?antagonist and activates?NF-κB?in lung tissue. Penehyclidine hydrochloride inhibits the release of inflammatory factors and shows anticholinergic properties.
价 格：￥电议型 号：T61233产 地：中国大陆
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T7127DC260126stress,DC260126,DC-260126,FFAR,Inhibitor,insulin,inhibit,secretion,Apoptosis,DC 260126,Free
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
价 格：￥电议型 号：T7127产 地：中国大陆
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T7519RS-127445 hydrochlorideInhibitor,RS127445,5-HT Receptor,inhibit,RS-127445,RS127445 hydrochloride,Ser
RS 127445 is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).
价 格：￥电议型 号：T7519产 地：中国大陆
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T12569LPSB-12379 ditriethylamine saltPSB 12379 disodium,PSB12379 disodium
PSB-12379 ditriethylamine salt, a nucleotide analogue, is a potent Ecto-5´-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).
价 格：￥电议型 号：T12569L产 地：中国大陆
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T6725VU 0357121inhibit,VU-0357121,VU 0357121,VU0357121,Inhibitor,Metabotropic glutamate receptors,mGluR
VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.
价 格：￥电议型 号：T6725产 地：中国大陆
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T15612JH-VIII-157-02CD246,Cluster of differentiation 246,inhibit,Anaplastic lymphoma kinase,Anaplastic lym
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.
价 格：￥电议型 号：T15612产 地：中国大陆
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T12721Rho-Kinase-IN-1Rho Kinase IN 1,RhoKinaseIN1
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation diseases.
价 格：￥电议型 号：T12721产 地：中国大陆
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T60122AldometanibCompoundIA47
Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib prevents FBP from binding to v-ATPase-associated aldolase and activates lysosomal AMPK. Aldometanib can be used for the research of metabolic homeostasis [1].
价 格：￥电议型 号：T60122产 地：中国大陆
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T6775BAY 41-2272Inhibitor,inhibit,Guanylate Cyclase,BAY 41 2272,BAY 412272,BAY 41-2272
BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator.
价 格：￥电议型 号：T6775产 地：中国大陆
