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  • T67254N-XantPhos Pd G3；化合物 Methanesulfonato[4,6-bis(diphenylphosphino)phenoxazine](2’-amino-1,1’-biphenyl-

    Methanesulfonato[4,6-bis(diphenylphosphino)phenoxazine](2´-amino-1,1´-biphenyl-2-yl)palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T67254.

    价 格：￥电议型 号：T67254产 地：中国大陆

  • T66254(R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-

    (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one is a useful organic compound for research related to life sciences and the catalog number is T66254.

    价 格：￥电议型 号：T66254产 地：中国大陆

  • T65254N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine；化合物 N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginineN2-(ter

    N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine is a useful organic compound for research related to life sciences. The catalog number is T65254 and the CAS number is 50913-12-7.

    价 格：￥电议型 号：T65254产 地：中国大陆

  • T64254EGFR/HER2-IN-5；化合物 EGFR/HER2-IN-5EGFR/HER2-IN-5

    EGFR/HER2-IN-5 is an irreversible, orally active dual inhibitor of EGFR activity (IC50: 0.6 nM). EGFR/HER2-IN-4 shows potent EGFR kinase inhibitory activity against L858R and T790M mutations. EGFR/HER2-IN-4 exhibits significant anti-tumour effects in vivo and can be used to study lung cancer.

    价 格：￥电议型 号：T64254产 地：中国大陆

  • T63254BTK-IN-11；化合物 BTK-IN-11BTK-IN-11

    BTK-IN-11 is a potent inhibitor of BTK. BTK-IN-11 has shown potential for research in diseases related to autoimmune diseases, inflammatory diseases or cancer.

    价 格：￥电议型 号：T63254产 地：中国大陆

  • T62549Antiproliferative agent-7；化合物 Antiproliferative agent-7Antiproliferative agent-7

    Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.

    价 格：￥电议型 号：T62549产 地：中国大陆

  • T62548ATR-IN-17；化合物 ATR-IN-17ATR-IN-17

    ATR-IN-17 is a potent inhibitor of ATR kinase with good anti-cancer effects in LoVo cells (IC50: 1 nM).

    价 格：￥电议型 号：T62548产 地：中国大陆

  • T62547HPK1-IN-17；化合物 HPK1-IN-17HPK1-IN-17

    HPK1-IN-17 is a selective and potent inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1) is a member of the MAP4Ks family and was originally cloned from hematopoietic progenitor cells. HPK1-IN-17 can be used to study, prevent or ameliorate diseases or conditions associated with HPK1 activity (e.g., cancer).

    价 格：￥电议型 号：T62547产 地：中国大陆

  • T62546ALK5-IN-27；化合物 ALK5-IN-27ALK5-IN-27

    ALK5-IN-27 (Compound EX-04) is a potent inhibitor of ALK-5 (IC50 ≤ 10 nM). ALK5-IN-27 also inhibits ALK-2.

    价 格：￥电议型 号：T62546产 地：中国大陆

  • T62545HDAC-IN-43；化合物 HDAC-IN-43HDAC-IN-43

    HDAC-IN-43 is a potent HDAC 1/3/6 inhibitor with IC50 values of 82 nM for HDAC 1, 45 nM for HDAC 3, and 24 nM for HDAC 6. HDAC-IN-43 is a weak PI3K/mTOR inhibitor with IC50 values of 3.6 μM for PI3K and 3.7 μM for mTOR. HDAC-IN-43 has a broad-spectrum anti-proliferative effect.

    价 格：￥电议型 号：T62545产 地：中国大陆

  • T62544MK-8153；化合物 MK-8153MK-8153

    MK-8153 is a selective, potent, orally active inhibitor of extrarenal medullary potassium channels (ROMK), acting on ROMK EP (IC50: 5 μM) and hERG EP (IC50: 34 μM).MK-8153 can be used as a diuretic.

    价 格：￥电议型 号：T62544产 地：中国大陆

  • T62543JNc-440；化合物 JNc-440JNc-440

    JNc-440 is a potent anti-hypertensive agent. jNc-440 enhances the interaction between the transient receptor potential vanilloid subtype 4 (TRPV4) and calcium-activated potassium channel 3 (KCa2.3) in endothelial cells. jNc-440 also increases vasodilation and has hypotensive activity in mice.

    价 格：￥电议型 号：T62543产 地：中国大陆

  • T62542GPR40 agonist 5；化合物 GPR40 agonist 5GPR40 agonist 5

    GPR40 agonist 5 is an orally active GPR40 (G protein-coupled receptor 40) agonist (EC50: 47 nM). gPR40 agonist 5 reduces blood glucose levels and improves glucose tolerance. gPR40 agonist 5 shows adequate control of hyperglycemic state in type 2 diabetic mice.

    价 格：￥电议型 号：T62542产 地：中国大陆

  • T62541AChE-IN-22；化合物 AChE-IN-22AChE-IN-22

    AChE-IN-22 (compound 10q) is a selective inhibitor of acetylcholinesterase (AChE) that acts on both AChE (IC50: 0.88 μM) and BuChE (IC50: 10 μM). AChE-IN-22 binds to both the CAS (catalytic active site) and PAS (peripheral anionic site) sites of AChE and can be used to study Alzheimer´s disease.

    价 格：￥电议型 号：T62541产 地：中国大陆

  • T62540PARP1/BRD4-IN-2；化合物 PARP1/BRD4-IN-2PARP1/BRD4-IN-2

    PARP1/BRD4-IN-2 is a potent and selective inhibitor of PARP1 (IC50: 197 nM) and BRD4 (IC50: 238 nM).PARP1/BRD4-IN-2 inhibits DNA damage repair, blocks the G0/G1 cell cycle transition, and induces apoptosis.PARP1/BRD4-IN-2 exhibits antitumor effects in the MDA-MB-468 mouse xenograft tumor model.PARP1/BRD4-IN-2 has been used to study the antitumor effects of PARP1/BRD4-IN-2 in triple-negative breast cancer (MDA-MB-468). PARP1/BRD4-IN-2 exhibits antitumor effects in the MDA-MB-468 mouse xenograft t

    价 格：￥电议型 号：T62540产 地：中国大陆

  • T6254Idasanutlin；依达奴林RG7388|||Ro 5503781；RG7388|||Ro 5503781|||依达奴林

    Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).

    价 格：￥电议型 号：T6254产 地：中国大陆

  • T62440TCMDC-125431；化合物 TCMDC-125431TCMDC-125431

    TCMDC-125431 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystals.

    价 格：￥电议型 号：T62440产 地：中国大陆

  • T62356Mardepodect hydrochloride；Mardepodect 盐酸盐PF-2545920 HCl|||Mardepodect HCl|||MP-10 HCl|||PF-02545920

    Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM).Mardepodect hydrochloride up-regulates the expression of proteins encoding specific growth and transcription factors, cell signalling molecules and cell surface proteins. Mardepodect hydrochloride upregulates genes encoding specific growth factors, transcription factors, cell signalling molecules, and cell surface proteins, while downregul

    价 格：￥电议型 号：T62356产 地：中国大陆

  • T62254TLR9-IN-1；化合物 TLR9-IN-1TLR9-IN-1

    TLR9-IN-1 is a selective and potent TLR9 inhibitor that acts on human TLR9 (IC50: 7 nM). TLR9-IN-1 can be used in the study of adverse immune response-related diseases.

    价 格：￥电议型 号：T62254产 地：中国大陆

  • T61917TCMDC-125457；化合物 TCMDC-125457TCMDC-125457

    TCMDC-125457 can effectively induce calcium redistribution, but has little effect on inhibiting heme crystallization. When TCMDC-125457 is combined with artesunate, it can effectively treat tightly synchronized artemisinin-resistant ring-stage parasites.

    价 格：￥电议型 号：T61917产 地：中国大陆

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