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  • T64390Triclopyr 2-butoxyethyl ester；绿草定-2-丁氧基乙酯Triclopyr-butotyl；Triclopyr-butotyl

    Triclopyr 2-butoxyethyl ester (Triclopyr-butotyl) is a bioactive substance. Triclopyr 2-butoxyethyl ester shows toxicity to Apis mellifera.

    价 格：￥电议型 号：T64390产 地：中国大陆

  • T64266KR-39038；化合物 KR-39038KR-39038

    KR-39038 is an orally active GRK5 (G protein-coupled receptor kinase 5) inhibitor (IC50: 0.02 μM). KR-39038 inhibits the HDAC5 pathway in neonatal cardiomyocytes and significantly inhibits angiotensin II-induced hypertrophy, resulting in significant anti-myocardial hypertrophy and improved cardiac function. KR-39038 can be used to conduct heart failure studies.

    价 格：￥电议型 号：T64266产 地：中国大陆

  • T63908hCAII-IN-4；化合物 hCAII-IN-4hCAII-IN-4

    hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM. Additionally, it demonstrates inhibition of β-glucuronidase, presenting an IC50 value of 773.9 μM [1].

    价 格：￥电议型 号：T63908产 地：中国大陆

  • T63907PDE5/HDAC-IN-1；化合物 PDE5/HDAC-IN-1PDE5/HDAC-IN-1

    PDE5/HDAC-IN-1 is a potent inhibitor of phosphodiesterase 5 (PDE5) and HDAC, with IC50 values of 46.3 nM and 14.5 nM, respectively.

    价 格：￥电议型 号：T63907产 地：中国大陆

  • T63906hGGPPS-IN-2；化合物 hGGPPS-IN-2hGGPPS-IN-2

    hGGPPS-IN-2 is an analogue of C-2 substituted thienopyrimidinyl bisphosphonates (C2-ThP-BPs) and is a potent inhibitor of human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-2 targets multiple myeloma (MM) cells, induces selective apoptosis, and shows anti-myeloma effects in vivo. It has shown anti-myeloma effects in vivo.

    价 格：￥电议型 号：T63906产 地：中国大陆

  • T63905Hesperadin hydrochloride；化合物 Hesperadin hydrochlorideHesperadin hydrochloride

    Hesperadin hydrochloride is an ATP-competitive indolone inhibitor of Aurora A and B, with an IC50 value of 250 nM for Aurora B.

    价 格：￥电议型 号：T63905产 地：中国大陆

  • T63904ATX inhibitor 19；化合物 ATX inhibitor 19ATX inhibitor 19

    ATX inhibitor 19 is a potent inhibitor of ATX (IC50: 156 nM).

    价 格：￥电议型 号：T63904产 地：中国大陆

  • T63903BPR1J-097 Hydrochloride；化合物 BPR1J-097 HydrochlorideBPR1J-097 Hydrochloride

    BPR1J-097 Hydrochloride is a novel, potent FLT3 inhibitor (IC50: 11 nM).

    价 格：￥电议型 号：T63903产 地：中国大陆

  • T63902XP-524；化合物 XP-524XP-524

    XP-524 is a potent inhibitor of BET and EP300. XP-524 has significant tumouricidal effects in vivo, preventing KRAS-induced tumour transformation in vivo and prolonging survival in two aggressive PDAC transgenic mouse models. XP-524 also enhances the expression of its own peptide and recruitment of tumour cells to cytotoxic T lymphocytes. XP-524 has shown potential for research in pancreatic ductal adenocarcinoma (PDAC).

    价 格：￥电议型 号：T63902产 地：中国大陆

  • T63901Axl-IN-8；化合物 Axl-IN-8Axl-IN-8

    Axl-IN-8 (NO.1) is a potent inhibitor of AXL (IC50<1 nM) and also inhibits c-MET (IC50: 1-10 nM). : 120.3 nM).

    价 格：￥电议型 号：T63901产 地：中国大陆

  • T63900VEGFR-2-IN-11；化合物 VEGFR-2-IN-11VEGFR-2-IN-11

    VEGFR-2-IN-11 is a potent inhibitor of VEGFR-2 (IC50: 60.27 nM) with an IC50 value of 60.27 nM, which induces apoptosis and has anticancer activity.

    价 格：￥电议型 号：T63900产 地：中国大陆

  • T6390Anagrelide hydrochloride；盐酸阿那格雷BMY 26538-01|||Anagrelide HCl|||Agrylin|||BL4162A；BMY 26538-01|||盐酸阿那

    Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.

    价 格：￥电议型 号：T6390产 地：中国大陆

  • T63390(S,S)-TAPI-1；化合物 (S,S)-TAPI-1(S,S)-TAPI-1

    (S,S)-TAPI-1 is an isomer of TAPI-1. Among them, TAPI-1 is a metalloproteinase (MMP) inhibitor and a TACE (ADAM17) inhibitor that exhibits potent inhibition of a variety of cell surface protein shedding.

    价 格：￥电议型 号：T63390产 地：中国大陆

  • T63004NUCC-390 dihydrochloride；化合物 NUCC-390 dihydrochlorideNUCC-390 dihydrochloride

    NUCC-390 dihydrochloride, a novel and selective CXCR4 receptor agonist, effectively induces the internalization of CXCR4 receptors and acts antagonistically to AMD3100 [1]. This small-molecule compound has demonstrated the ability to facilitate functional nerve recovery following neurodegeneration in vivo [2].

    价 格：￥电议型 号：T63004产 地：中国大陆

  • T62390CSF1R-IN-8；化合物 CSF1R-IN-8CSF1R-IN-8

    CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor (IC50: 0.012 μM).

    价 格：￥电议型 号：T62390产 地：中国大陆

  • T62219NN-390；化合物 NN-390NN-390

    NN-390 is a selective, potent HDAC6 inhibitor (IC50: 9.8 μM) that crosses the blood-brain barrier. nN-390 has potential for studies in metastatic group 3 neural tube cell tumours.

    价 格：￥电议型 号：T62219产 地：中国大陆

  • T61390D18；化合物 D18D18

    D18 is an immune modulator that acts as a dual agonist for TLR7/8 (with EC50 values of 24 nM for hTLR7 and 10 nM for hTLR8, respectively). It enhances the expression of PD-L1 through epigenetic regulation, thereby increasing the sensitivity of tumors to PD-1/PD-L1 blockade. Additionally, D18 functions as a cytotoxin for ADC synthesis, specifically for the ADC HE-S2 [1].

    价 格：￥电议型 号：T61390产 地：中国大陆

  • T60390PI-55；化合物PI-556-(2-hydroxy-3-methylbenzylamino)purine；6-(2-hydroxy-3-methylbenzylamino)purine

    PI-55 (6-(2-hydroxy-3-methylbenzylamino)purine) is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis receptors CRE1/AHK4 and AHK3. Furthermore, PI-55 effectively suppresses cytokinins-induced haustorium formation and enhances parasite aggressiveness [1].

    价 格：￥电议型 号：T60390产 地：中国大陆

  • T5539GS-443902瑞德西韦代谢物瑞德西韦代谢物

    Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 ?M, 5 ?M for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.

    价 格：￥电议型 号：T5539产 地：中国大陆

  • T5390BMS-599626 Hydrochloride；BMS-599626盐酸盐AC480 Hydrochloride；AC480 Hydrochloride

    BMS-599626 Hydrochloride (AC480 Hydrochloride) is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50 =22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 Hydrochloride inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.

    价 格：￥电议型 号：T5390产 地：中国大陆

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