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T6366A-966492化合物A9664922-[2-氟-4-[(2S)-2-吡咯烷基]苯基]-1H-苯并咪唑-7-甲酰胺
A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.
价 格：￥电议型 号：T6366产 地：中国大陆
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T63492BI-1622；化合物 BI-1622BI-1622
BI-1622 is a highly selective, orally active HER2(ERBB2) inhibitor (IC50: 7 nM). BI-1622 is >25-fold selective for EGFR. In a mouse model of transplanted tumors transfected with H2170 and PC9 cells, BI-1622 exhibited high in vivo antitumor effects with good drug metabolism and pharmacokinetic properties.
价 格：￥电议型 号：T63492产 地：中国大陆
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T6341PF04929113；化合物PF04929113PF-04929113|||SNX-5422|||PF 04929113；PF-04929113|||SNX-5422|||PF 04929113
PF04929113 (SNX-5422) is a synthetic, novel, small molecule Hsp90 Inhibitor. As an oral formulation that demonstrates strong efficacy and tolerability, PF04929113 is positioned as a breakthrough therapy with broad applicability across a wide range of cancers.
价 格：￥电议型 号：T6341产 地：中国大陆
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T6332Pevonedistat；化合物PevonedistatMLN4924；MLN4924
Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM). Pevonedistat can be used for the treatment of myelodysplastic syndromes (MDS) and also has antitumor activity.
价 格：￥电议型 号：T6332产 地：中国大陆
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T6305SNX2112；化合物SNX2112SNX-2112|||PF 04928473|||SNX 2112；SNX-2112|||PF 04928473|||SNX 2112
SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.
价 格：￥电议型 号：T6305产 地：中国大陆
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T6274RO4929097；化合物RO4929097RG-4733；RG-4733
RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).
价 格：￥电议型 号：T6274产 地：中国大陆
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T62396LKB-5492 FA；KB-5492 甲酸盐KB-5492 FA（113594-64-2 Free base）；KB-5492 FA（113594-64-2 Free base）
KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS ??128-52-56-8
价 格：￥电议型 号：T62396L产 地：中国大陆
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T62396KB-5492 free base；化合物 KB-5492 free baseKB-5492 free base
KB-5492 free base is an orally available and selective antiulcer agent that inhibits sigma receptors, inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors, and may be useful in the study of gastric lesions and gastric secretion.
价 格：￥电议型 号：T62396产 地：中国大陆
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T61492Idoxuridine hydrate；化合物 Idoxuridine hydrateIdoxuridine hydrate
Idoxuridine hydrate (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is a competitive inhibitor of phosphorylases. As an iodinated thymidine analogue, it effectively inhibits DNA polymerase and hinders viral replication, making it useful in the treatment of viral eye infections such as herpes simplex keratitis. Against feline herpesvirus, Idoxuridine has been found to have an IC50 value of 4.3 μM [1].
价 格：￥电议型 号：T61492产 地：中国大陆
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T60629PF-06649298；化合物 PF-06649298PF-06649298
PF-06649298 is an inhibitor of sodium-coupled citrate transporter which specifically interacts with NaCT with an IC 50 value of 16.2 μM to inhibits the transport of citrate in human hepatocytes. PF-06649298 can be used in regulating metabolism of glucose and metabolism of lipid [1] [2].
价 格：￥电议型 号：T60629产 地：中国大陆
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T60492Lamotrigine hydrate；化合物 Lamotrigine hydrateLamotrigine hydrate
Lamotrigine hydrate is an effective oral active anticonvulsant or antiepileptic agent that selectively blocks voltage-gated Na + channels, stabilizes presynaptic neuronal membranes and inhibits glutamate release. Lamotrigine hydrate can be used in epilepsy, focal seizure, et al [1] [2].
价 格：￥电议型 号：T60492产 地：中国大陆
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T5S1058Triptonide；雷公藤内酯酮PG 492|||NSC 165677；雷公藤内酯酮|||PG 492|||NSC 165677
1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, and this expression was suppressed by ERK1/2 and p38 MAPK inhibitors.
价 格：￥电议型 号：T5S1058产 地：中国大陆
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T5492JAK3-IN-6；化合物JAK3-IN-6JAK3-IN-6
JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nM
价 格：￥电议型 号：T5492产 地：中国大陆
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T5179AVN-492；化合物AVN-492AVN492；AVN492
AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).
价 格：￥电议型 号：T5179产 地：中国大陆
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T5164Cabozantinib hydrochloride；盐酸卡博替尼XL184|||Cabozantinib hydrochloride (849217-68-1(free base))|||BMS-9
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
价 格：￥电议型 号：T5164产 地：中国大陆
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T5099Gefapixant；化合物GefapixantRO 4926219|||AF219|||MK-7264；RO 4926219|||AF219|||MK-7264
Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
价 格：￥电议型 号：T5099产 地：中国大陆
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T4929L-2-Phosphoglyceric acid；化合物 L-2-Phosphoglyceric acidL-2-Phosphoglyceric acid disodium salt h；L-GLYC
L-2-Phosphoglyceric acid (L-2-Phosphoglyceric acid disodium salt) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate.
价 格：￥电议型 号：T4929产 地：中国大陆
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T4928L-Kynurenine；L-犬尿氨酸(S)-Kynurenine；L-犬尿氨酸|||(S)-Kynurenine
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
价 格：￥电议型 号：T4928产 地：中国大陆
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T49274-Guanidinobutanoic acid；4-胍基丁酸4-GBA|||4-Guanidinobutyric acid；4-GBA|||4-胍基丁酸|||4-Guanidinobutyric a
4-Guanidinobutanoic acid (4-GBA) is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid transporters hPAT1.
价 格：￥电议型 号：T4927产 地：中国大陆
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T4925Thiamine monophosphate chloride (dihydrate)胺氯化亚磷酸酯Thiamine monophosphate chloride dihydrat|||胺氯化亚磷酸酯
Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) is a compound used in the screening of ligands that promote protein stability
价 格：￥电议型 号：T4925产 地：中国大陆
