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  • T75019Antituberculosis agent-7；化合物 Antituberculosis agent-7Antituberculosis agent-7

    Antituberculosis agent-7, an oxetanyl-quinoline derivative, exhibits potent antibacterial activity against P. mirabilis, with a minimum inhibitory concentration (MIC) of 31.25 μM, and antifungal efficacy against A. niger, with a MIC of 62.5 μM. Furthermore, it demonstrates remarkable antimycobacterial activity, achieving a MIC of 3.41 μM against M. tuberculosis H37Rv [1].

    价 格：￥电议型 号：T75019产 地：中国大陆

  • T75017PROTAC HDAC6 degrader 1；化合物 PROTAC HDAC6 degrader 1PROTAC HDAC6 degrader 1

    Compound A6, a potent and selective PROTAC HDAC6 degrader, exhibits a DC50 of 3.5 nM. It demonstrates notable antiproliferative activity by inducing apoptosis in myeloid leukemia cell lines [1].

    价 格：￥电议型 号：T75017产 地：中国大陆

  • T75016Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal；化合物 Glucocorticoid receptor agonist-1 phosph

    Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal functions as a glucocorticoid receptor agonist, utilized in the formulation of anti-CD40 antibody agent conjugates (ADC). It serves as a research tool for exploring inflammation and immune regulation [1].

    价 格：￥电议型 号：T75016产 地：中国大陆

  • T75015HX103；化合物 HX103HX103

    HX103, an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-based fluorogenic probe, exhibits selective inhibition towards various EGFR mutations, including EGFR 19 del, EGFR L858R, EGFR wild type, and EGFR T790M, with respective IC50 values of 1.3, 1.5, 4.0, and 977 nM. It is utilized for quantifying active-EGFR to foresee agent sensitivity in NSCLC (non-small cell lung cancer) patients harboring EGFR-activating mutations [1].

    价 格：￥电议型 号：T75015产 地：中国大陆

  • T75014Antiproliferative agent-18；化合物 Antiproliferative agent-18Antiproliferative agent-18

    Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].

    价 格：￥电议型 号：T75014产 地：中国大陆

  • T75013SB26019；化合物 SB26019SB26019

    SB26019 is a potent anti-neuroinflammatory compound that modulates the activation of NF-κB by promoting the formation of monomeric α-tubulin. This action of SB26019, in turn, hinders the translocation of p65, signifying its regulatory effect on neuroinflammatory processes [1].

    价 格：￥电议型 号：T75013产 地：中国大陆

  • T75012SIAIS100；化合物 SIAIS100SIAIS100

    SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy. It is primarily utilized in the investigation of chronic myeloid leukemia (CML) [1].

    价 格：￥电议型 号：T75012产 地：中国大陆

  • T75011STING-IN-5；化合物 STING-IN-5STING-IN-5

    STING-IN-5, a potent inhibitor of the Stimulator of Interferon Genes (STING) pathway, significantly suppresses lipopolysaccharide (LPS)-induced nitric oxide (NO) synthesis in macrophages, exhibiting an IC50 of 1.15 μM. This compound dampens the inflammatory response and offers potential for research into anti-inflammatory diseases and sepsis [1].

    价 格：￥电议型 号：T75011产 地：中国大陆

  • T75010TD1092；化合物 TD1092TD1092

    TD1092, a pan-IAP degrader, effectively degrades cIAP1, cIAP2, and XIAP, catalyzing the activation of Caspase 3/7 and fostering apoptosis in cancer cells through IAP degradation. It also obstructs the TNFα-mediated NF-κB pathway, diminishing the phosphorylation of IKK, IkBα, p65, and p38, and operates as a PROTAC. This compound is utilized in cancer research [1].

    价 格：￥电议型 号：T75010产 地：中国大陆

  • T7501Iso-H7 dihydrochloride1-(5-硫代异喹啉)-3-甲基哌嗪二盐酸盐1-(5-硫代异喹啉)-3-甲基哌嗪二盐酸盐

    Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.

    价 格：￥电议型 号：T7501产 地：中国大陆

  • T74865BK50164；化合物 BK50164BK50164

    BK50164, a potent CD73 inhibitor, exhibits an IC50 of 13.089 ?M and demonstrates affinity for CD99 with a KD value of 1.5 ?M. This compound not only possesses antiproliferative activity but also induces apoptosis and cell cycle arrest at the Sub-G1 phase [1].

    价 格：￥电议型 号：T74865产 地：中国大陆

  • T74501NHEJ inhibitor-1；化合物 NHEJ inhibitor-1NHEJ inhibitor-1

    NHEJ Inhibitor-1 (Compound C2), a trifunctional Pt(II) complex, mitigates non-homologous end joining (NHEJ)/homologous recombination (HR)-related double strand break (DSB) repairs, combating Cisplatin resistance in non-small cell lung cancer (NSCLC). It achieves this by inhibiting the damage repair proteins Ku70 and Rad51, thus re-sensitizing tumors to Cisplatin. Additionally, this compound prompts the generation of reactive oxygen species (ROS) and reduces mitochondrial membrane potential (MMP)

    价 格：￥电议型 号：T74501产 地：中国大陆

  • T7417Avatrombopag；化合物AvatrombopagYM477|||AKR-501|||E5501；YM477|||AKR-501|||1-[3-氯-5-[[[4-(4-氯-2-噻吩基)-5-(4

    Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.

    价 格：￥电议型 号：T7417产 地：中国大陆

  • T73501MC0704；化合物 MC0704MC0704

    MC0704 is a STAT3 inhibitor that demonstrates antitumor activity specifically in mouse breast cancer models, possessing an IC50 value of 2.13 μM. It is effective in inducing cell apoptosis and cell cycle arrest, making it a potential candidate for researching metastatic triple-negative breast cancer (mTNBC).

    价 格：￥电议型 号：T73501产 地：中国大陆

  • T73053BAY 2965501；化合物BAY 2965501BAY 2965501

    BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that induces pERK activation.BAY 2965501 can be used in the study of cancer.

    价 格：￥电议型 号：T73053产 地：中国大陆

  • T7297KG-501；色酚AS-E磷酸盐Naphthol AS-E phosphate；Naphthol AS-E phosphate|||色酚AS-E磷酸盐

    KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).

    价 格：￥电议型 号：T7297产 地：中国大陆

  • T72501CYP4A11/CYP4F2-IN-1；CYP4A11/CYP4F2 抑制剂 1CYP4A11/CYP4F2-IN-1

    CYP4A11/CYP4F2-IN-1 is a cytochrome P450 (CYP) 4A11 and CYP4F2 inhibitor. CYP4A11/CYP4F2-IN-1 can be used to study kidney diseases and cardiovascular and cerebrovascular diseases.

    价 格：￥电议型 号：T72501产 地：中国大陆

  • T71627CX-5011；化合物 CX-5011CX-5011

    CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2].

    价 格：￥电议型 号：T71627产 地：中国大陆

  • T71522FLM-5011；化合物 FLM-5011FLM-5011

    FLM-5011 is a a lipoxygenase inhibitor with anti-inflammatory effects.

    价 格：￥电议型 号：T71522产 地：中国大陆

  • T71501GBS-149；化合物 GBS-149GBS-149

    GBS-149 is a novel non-toxic and mammalian-specific LINE-1 inhibitor.

    价 格：￥电议型 号：T71501产 地：中国大陆

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