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T13214LTRPV4 agonist-1 free baseOUN67600
TRPV4 agonist-1 free base is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).
价 格:¥电议型 号:T13214L产 地:中国大陆
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T12933SM-276001
SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.
价 格:¥电议型 号:T12933产 地:中国大陆
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T12192NCGC00229600
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves´ disease studies.
价 格:¥电议型 号:T12192产 地:中国大陆
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T11600IBR2Isoquinoline
IBR2 is a potent and specific RAD51 inhibitor that inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth, and induces apoptosis.
价 格:¥电议型 号:T11600产 地:中国大陆
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T060010,11-DihydrocarbamazepineDihydrocarbamazepine;双氢卡马西平;10,11-二氢卡马西平
10,11-Dihydrocarbamazepine is used as pharmaceutical intermediates.
价 格:¥电议型 号:T0600产 地:中国大陆
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T10749Cebranopadol ((1α,4α)stereoisomer)Cebranopadol ((1α,4α)stereoisomer),GRT6005 (1α,4α)stereoisomer,
Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol which is a potent ORL-1 agonist.
价 格:¥电议型 号:T10749产 地:美洲
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T12647(R)-VU 6008667(R)-VU 6008667
(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).
价 格:¥电议型 号:T12647产 地:美洲
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T12679(Rac)-VU 6008667(Rac)-VU 6008667
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50 of 1.8 μM and pIC50 of 5.75, has high CNS penetration.
价 格:¥电议型 号:T12679产 地:美洲
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T12809(S)-PF-06873600(S)-PF-06873600
(S)-PF-06873600 is the S enantiomer of PF-06873600. PF-06873600 is a selective and orally bioavailable CDK inhibitor.
价 格:¥电议型 号:T12809产 地:美洲
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T12809LPF-06873600PF-06873600
PF-06873600 has potential antineoplastic activity. PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (Ki: 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively).
价 格:¥电议型 号:T12809L产 地:美洲
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T13321VU6005649VU6005649
VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor(EC50s of 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).
价 格:¥电议型 号:T13321产 地:美洲
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T13600CDD3505CDD3505
CDD3505 is used for elevating high-density lipoprotein cholesterol (HDL) by inducing hepatic CYP3A activity.
价 格:¥电议型 号:T13600产 地:美洲
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T15791LUF6000LUF6000
LUF6000 is an allosteric modulator of the human A3 adenosine receptor (AR).
价 格:¥电议型 号:T15791产 地:美洲
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T16007MALAT1-IN-1MALAT1-IN-1
MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting the expression of nuclear enriched abundant transcript 1 (Neat1). MALAT1-IN-1 is an effective and specific Malat1 inhibitor.
价 格:¥电议型 号:T16007产 地:美洲
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T19600Vanilpyruvic acidVanilpyruvic acid,Vanylpyruvic acid,
Vanilpyruvic acid is a metabolite of catecholamine and precursor of vanillactic acid.
价 格:¥电议型 号:T19600产 地:美洲
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T2367SKF-86002SKF-86002,SKF86002,SKF 86002
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
价 格:¥电议型 号:T2367产 地:美洲
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T2474KU-60019KU-60019,KU60019,KU 60019
Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.
价 格:¥电议型 号:T2474产 地:美洲
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T2600AG-490AG-490,AG490,AG 490
AG-490 (Tyrphostin AG 490) is an inhibitor of EGFR (IC50: 0.1 μM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.
价 格:¥电议型 号:T2600产 地:美洲
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T4600BMS-3BMS-3,BMS3,BMS 3
BMS-3 is a potent?LIMK?inhibitor with?IC50s of 5 nM and 6 nM for?LIMK1?and?LIMK2, respectively.
价 格:¥电议型 号:T4600产 地:美洲