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T68663GPI-15427；化合物 GPI-15427GPI-15427
GPI-15427 is a potent PARP-1 inhibitor capable of crossing the blood-brain barrier, which can significantly increased the antitumor activity of the methylating agent TMZ against malignant melanoma, glioblastoma multiforme, or lymphoma growing at the CNS site. GPI-15427 acts as a potent inhibitor of the enzyme, being capable of inhibiting the activity of purified PARP-1 at nanomolar concentrations. GPI-15427 induced significant sensitization to radiotherapy, representing a promising new treatment
价 格：￥电议型 号：T68663产 地：中国大陆
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T68661Edatrexate；化合物 EdatrexateCGP 30694；CGP 30694
Edatrexate (CGP 30694), also known as 10-Ethyl-10-deazaaminopterin, is an analog of Methotrexate that demonstrates antitumor activity against Methotrexate-resistant tumors. This antifolate antimetabolite is utilized in research related to non-small-cell lung cancer, breast cancer, non-Hodgkin´s lymphoma, and head and neck cancer [1] [2].
价 格：￥电议型 号：T68661产 地：中国大陆
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T68660Polignate Sodium；化合物 Polignate SodiumPolignate Sodium
Polignate Sodium is an Enzyme Inhibitor (Pepsin)
价 格：￥电议型 号：T68660产 地：中国大陆
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T6866AUZ 454；化合物K03861K03861；K03861
AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.
价 格：￥电议型 号：T6866产 地：中国大陆
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T68659Valyl-glycyl-arginine-4-nitroanilide；化合物 Valyl-glycyl-arginine-4-nitroanilideValyl-glycyl-arginine-4
Valyl-glycyl-arginine-4-nitroanilide is a tissue plasminogen activator.
价 格：￥电议型 号：T68659产 地：中国大陆
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T68657Asulacrine isethionate；化合物 Asulacrine isethionateAsulacrine isethionate
Asulacrine isethionate, also known as CI-921; NSC-343499; SN-21407, is a topoisomerase ll inhibitor with antineoplastic properties. Asulacrine isethionate inhibits the enzyme topoisomerase ll, thereby blocking DNA replication and RNA and protein synthesis.
价 格：￥电议型 号：T68657产 地：中国大陆
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T68656Brivudine monophosphate；化合物 Brivudine monophosphateBrivudine monophosphate
Brivudine monophosphate is a phosphate ester of Brivudine. Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator
价 格：￥电议型 号：T68656产 地：中国大陆
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T68655PAN12314；化合物 PAN12314PAN12314
PAN12314, also known as Compound 5a, is a 5-HT4R partial agonists that displayed cognition-enhancing properties in animal models. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
价 格：￥电议型 号：T68655产 地：中国大陆
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T68654Sapintoxin D；化合物 Sapintoxin DSapintoxin D
Sapintoxin D is a fluorescent phorbol ester and selective activator of protein kinase C.
价 格：￥电议型 号：T68654产 地：中国大陆
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T68653YC-137；化合物 YC-137YC-137
YC-137 is a BCL-2 inhibitor, which selectively induces apoptosis of Bcl-2-overexpressing cells and disrupts its interaction with Bid BH3, thereby blocking the anti-apoptotic activity of Bcl-2.
价 格：￥电议型 号：T68653产 地：中国大陆
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T68652Carmegliptin dihydrochloride；化合物 Carmegliptin dihydrochlorideCarmegliptin dihydrochloride
Carmegliptin dihydrochloride is the salt form of Camegliptin (free base), also known as RG-1579 and RO4876904, a dipeptidyl peptidase IV (DPP-4) inhibitor potentially for the treatment of type 2 diabetes.
价 格：￥电议型 号：T68652产 地：中国大陆
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T68651ICI-105552；化合物 ICI-105552ICI-105552
ICI-105552 is an aldose reductase inhibitor.
价 格：￥电议型 号：T68651产 地：中国大陆
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T68650AH 23848；化合物 AH 23848AH 23848
AH 23848 is a Thromboxane antagonist which accelerates inducible nitric oxide synthase degradation through attenuation of cAMP signaling in glomerular mesangial cells.
价 格：￥电议型 号：T68650产 地：中国大陆
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T68649Dexlofexidine Free Base；化合物 Dexlofexidine Free BaseDexlofexidine Free Base
Dexlofexidine Free Base is an isomer “+“ of lofexidine, which is an agonist of alpha 2-adrenoceptor, but in 10 times less potent than the other isomer, levlofexidine
价 格：￥电议型 号：T68649产 地：中国大陆
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T68648Diprafenone Free Base；化合物 Diprafenone Free BaseDiprafenone Free Base
Diprafenone Free Base is an antiarrhythmic beta adrenergic antagonist.
价 格：￥电议型 号：T68648产 地：中国大陆
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T68646Dalbraminol；化合物 DalbraminolDalbraminol
Dalbraminol is a beta blocker.
价 格：￥电议型 号：T68646产 地：中国大陆
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T68645Hexamethonium monotartrate；化合物 Hexamethonium monotartrateHexamethonium monotartrate
Hexamethonium monotartrate is a non-depolarizing NMJ blocker and nAChR antagonist. It has previously been used to treat hypertension. It inhibits sympathetic nervous system activity and acts as a skeletal muscle relaxant.
价 格：￥电议型 号：T68645产 地：中国大陆
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T68644Pca 4233；化合物 Pca 4233Pca 4233
Pca 4233 belongs to a class of selective PAF-receptor antagonists.
价 格：￥电议型 号：T68644产 地：中国大陆
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T68643S-(?)-SKF-38393 hydrochloride；化合物 S-(?)-SKF-38393 hydrochlorideS-(?)-SKF-38393 hydrochloride
S-(?)-SKF-38393 hydrochloride is a D1 dopamine receptor agonist.
价 格：￥电议型 号：T68643产 地：中国大陆
