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T60950Pirepemat fumarate;化合物 Pirepemat fumaratePirepemat fumarate
Pirepemat (IRL752) fumarate can be used in Parkinson´s disease study. Pirepemat is a cortical-preferring catecholamine transmission- and cognition-promoting agent [1] [2].
价 格:¥电议型 号:T60950产 地:中国大陆
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T60603BRD9500;化合物 BRD9500BRD9500
BRD9500 is an orally active inhibitor of phosphodiesterases 3 (PDE3) with IC 50 s of 10 and 27 nM for PDE3A and PDE3B, respectively. BRD9500 is active in an SK-MEL-3 xenograft model of cancer [1].
价 格:¥电议型 号:T60603产 地:中国大陆
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T49501,2-Dipalmitoyl-sn-glycerol;1,2-双棕榈酸甘油酯(S)-1,2-Dipalmitin;1,2-双棕榈酸甘油酯|||(S)-1,2-Dipalmitin
1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.
价 格:¥电议型 号:T4950产 地:中国大陆
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T40950A3334;A3334A3334
A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD) and methionine-choline deficient diet (MCD).
价 格:¥电议型 号:T40950产 地:中国大陆
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T39950Thalidomide-amido-PEG2-NH2;Thalidomide-amido-PEG2-NH2Thalidomide-amido-PEG2-NH2;Thalidomide-amido-PE
Thalidomide-amido-PEG2-NH2 is a synthetic conjugate of an E3 ligase ligand-linker that combines the Thalidomide-based cereblon ligand with a linker commonly utilized in PROTAC technology.
价 格:¥电议型 号:T39950产 地:中国大陆
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T39509DBCO-PEG3-amine;DBCO-PEG3-amineDBCO-PEG3-amine;DBCO-PEG3-amine
DBCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39509产 地:中国大陆
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T39508KY-02327;化合物KY-02327KY-02327
KY-02327, a metabolically stabilized analog of KY-02061, serves as a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction. This compound activates the Wnt/β-catenin pathway, thereby promoting osteoblast differentiation.
价 格:¥电议型 号:T39508产 地:中国大陆
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T39507LFosgonimeton acetate;化合物Fosgonimeton acetateFosgonimeton acetate (2093305-05-4 Free base);Fosgonimet
Fosgonimeton acetate is an agonist of hepatocyte growth factor (HGF).
价 格:¥电议型 号:T39507L产 地:中国大陆
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T39507Fosgonimeton;FosgonimetonATH-1017;ATH-1017
Fosgonimeton is a hepatocyte growth factor receptor agonist (WO2017210489).
价 格:¥电议型 号:T39507产 地:中国大陆
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T39506Fmoc-NH-PEG5-C2-NH2;Fmoc-NH-PEG5-C2-NH2Fmoc-NH-PEG5-C2-NH2;Fmoc-NH-PEG5-C2-NH2
Fmoc-NH-PEG5-C2-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39506产 地:中国大陆
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T39505Ethyl acetate-PEG1;Ethyl acetate-PEG1Ethyl acetate-PEG1;Ethyl acetate-PEG1
Ethyl acetate-PEG1 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39505产 地:中国大陆
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T39504PA Janelia Fluor? 646, SE;PA Janelia Fluor? 646, SEPA-JF646-NHS;PA-JF646-NHS
PA Janelia Fluor 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag and SNAP-tag . PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λ Excitation/emission ~650/664 nm).
价 格:¥电议型 号:T39504产 地:中国大陆
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T39503Hepatitis Virus C NS3 Protease Inhibitor 2;Hepatitis Virus C NS3 Protease Inhibitor 2Hepatitis Virus
Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by a Ki value of 41 nM.
价 格:¥电议型 号:T39503产 地:中国大陆
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T39502Lipid 5;Lipid 5Lipid 5
Lipid 5 is an amino lipid compound that demonstrates proficient mRNA delivery in rodent and primate models, displaying favorable pharmacokinetics and minimal toxicity.
价 格:¥电议型 号:T39502产 地:中国大陆
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T39501Anticancer agent 7;Anticancer agent 7Anticancer agent 7
Anticancer agent 7 (Example 5) is an anti-cancer agent that exhibits potent anticancer activity against H1650 lung cancer cells, with an IC50 value of 5 μM.
价 格:¥电议型 号:T39501产 地:中国大陆
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T39500Acid-PEG3-SSPy;Acid-PEG3-SSPyAcid-PEG3-SSPy;Acid-PEG3-SSPy
Acid-PEG3-SSPy is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39500产 地:中国大陆
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T3950Tridecanoic acid;十三酸n-Tridecoic Acid|||n-Tridecanoic Acid|||Tridecylic Acid;n-Tridecoic Acid|||n-Tri
Tridecanoic acid (Tridecylic Acid) is a 13-carbon saturated fatty acid found in dairy products and also as a product of anaerobic biodegradation of n-hexadecane. It has been identified as a substrate of phospholipase A2.
价 格:¥电议型 号:T3950产 地:中国大陆
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T38619GSK1795091GSK1795091CRX-601
GSK1795091 (CRX-601) is a synthetic TLR4 agonist and immunologic stimulator with demonstrated antitumor activity. It serves as a vaccine adjuvant, enhancing both mucosal and systemic immunity to influenza virus vaccines.
价 格:¥电议型 号:T38619产 地:中国大陆
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T379502-(Isopentylamino)naphthalene-1,4-dione;2-(Isopentylamino)naphthalene-1,4-dione2-(Isopentylamino)nap
2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).
价 格:¥电议型 号:T37950产 地:中国大陆
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T3701MCC950;化合物MCC950CP-456773;CP-456773
CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically inhibited activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes. MCC950 reduced IL-1β production in vivo and attenuated the severity of experimental autoimmune encephalomyelitis (EAE), a
价 格:¥电议型 号:T3701产 地:中国大陆