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TQ0184Chebulinic acidInhibitor,Transforming growth factor beta,inhibit,Proton Pump,DNA/RNA Synthesis,Chebu
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
价 格:¥电议型 号:TQ0184产 地:中国大陆
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TP1330Cyclo(RADfK)Cyclo(RADfK),Inhibitor,inhibit,Integrin
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD peptides are modulators of cell adhesion and are recognized by several members of the integrin family.
价 格:¥电议型 号:TP1330产 地:中国大陆
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T8369Adagrasibinhibit,GDP-bound,mutant,MIA PaCa-2,MRTX-849,Adagrasib,selective,Inhibitor,MRTX 849,inactiv
MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. It selectively modifies mutant cysteine 12 in GDP-bound KRASG12C, and inhibits KRAS-dependent signaling.
价 格:¥电议型 号:T8369产 地:中国大陆
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TP1474LXW7LXW7,Integrin,Anti-inflammatory,Inhibitor,LXW-7,ERK1/2,VEGFR-2,LXW 7,αvβ3,inhibit
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-peptide (cGRGDdvc) containing unnatural amino acids flanking both sides of the main functional motif.
价 格:¥电议型 号:TP1474产 地:中国大陆
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TN1936Mogroside III-Einhibit,Inhibitor,Mogroside IIIE,Mogroside III E,Mogroside III-E
Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in mice partly through regulation of the TLR4/MAPK/NF-κB axis via AMPK activation. It also has anti-fibrotic activity, it reduces pulmonary fibrosis through Toll-Like receptor 4 pathways.
价 格:¥电议型 号:TN1936产 地:中国大陆
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TQ0256FGFR4-IN-1Fibroblast growth factor receptor,FGFR-4-IN-1,FGFR,inhibit,FGFR4IN1,Inhibitor,FGFR4 IN 1
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
价 格:¥电议型 号:TQ0256产 地:中国大陆
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TJS1748Methyl protogracillinMethyl protogracillin
Methyl protogracillin is a natural product from Dioscorea collettii var. hypoglauca with anti-cancer activity.
价 格:¥电议型 号:TJS1748产 地:中国大陆
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T7819TAS0728TAS 0728,Inhibitor,EGFR,ErbB-1,inhibit,TAS0728,HER1,TAS-0728,Epidermal growth factor receptor
TAS0728 is a HER2 inhibitor, with antitumor activity
价 格:¥电议型 号:T7819产 地:中国大陆
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T6S1101Astragalinantioxidant,proliferation,inhibit,Apoptosis,migration,Astragalin,anti-inflammatory,antican
1. Astragalin may be a potential agent in the treatment of osteoarthritis. 2. Astragalin can be effective in allaying ROS-promoted bronchial fibrosis through inhibiting autophagosome formation in airways. 3. Astragalin ameliorates oxidative stress-associated epithelial eosinophilia and apoptosis through disturbing TLR4-PKCβ2-NADPH oxidase-responsive signaling. 4. Astragalin exerts anti-inflammatory properties possibly via the inactivation of TLR4-mediated NF-κB and mitogen-activated protein kina
价 格:¥电议型 号:T6S1101产 地:中国大陆
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TQ0235AC710Fms like tyrosine kinase 3,Cluster of differentiation antigen 135,CD117,Platelet-derived growth
AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).
价 格:¥电议型 号:TQ0235产 地:中国大陆
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T6824EAI045Inhibitor,Epidermal growth factor receptor,ErbB-1,EGFR,EAI-045,EAI 045,inhibit,HER1,EAI045
EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.
价 格:¥电议型 号:T6824产 地:中国大陆
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TN1624Ethyl cinnamateInhibitor,fragrance,Ethyl cinnamate,inhibit,clearing,reagent
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl cinnamate can inhibit the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with respective IC50 values of 0.30 mM and 0.38 mM.
价 格:¥电议型 号:TN1624产 地:中国大陆
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T7526JNJ-17203212management,inhibit,pain,migrainem,Transient receptor potential channels,TRP Channel,JNJ-
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).
价 格:¥电议型 号:T7526产 地:中国大陆
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T9979WAY-302159Inhibitor,VEGFR,quinoline amide,inhibit,WAY 302159,HUVEC,Vascular endothelial growth facto
WAY-302159 is a VEGFR2 inhibitor.
价 格:¥电议型 号:T9979产 地:中国大陆
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T9120HBCgreen,GFP,fluorophore-like,fluorescent,synthetic,HBC,Inhibitor,inhibit,dye
HBC 530 is a mimic of green fluorescent protein (GFP) fluorophore for imaging RNA in live cells. Fluoresces when bound to Pepper aptamer; displays high affinity binding (Kd = 3.5 nM). Suitable for confocal and two-photon microscopy. Confocal excitation maximum = 488 nm, emission maximum= 495 - 595 nm. Two-photon excitation maximum = 976 nm, emission maximum= 475 - 575 nm.
价 格:¥电议型 号:T9120产 地:中国大陆
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T6S1740Nardosinonecells,Nardosinone,Neurite,substances,PC12D,outgrowth-promoting,neuritogenic,inhibit,MAPK,
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and stau
价 格:¥电议型 号:T6S1740产 地:中国大陆
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T2288LMotesanib DiphosphateMotesanib Diphosphate,c-Kit,inhibit,AMG 706 Diphosphate,Vascular endothelial gr
Motesanib Diphosphate is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity.
价 格:¥电议型 号:T2288L产 地:中国大陆
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T6382Amikacin disulfateBacterial,bacillary,aminoglycosides,Gram-negative,ototoxic,Inhibitor,BAY 41-6551 d
Amikacin sulfate(BAY416651 sulfate) is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A.
价 格:¥电议型 号:T6382产 地:中国大陆
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T7566LGRGDSPK 2TFA(111119-28-9(free base))GRGDSPK 2TFA(111119 28 9(free base)),GRGDSPK 2TFA(111119289(free
GRGDSPK 2TFA is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.
价 格:¥电议型 号:T7566L产 地:中国大陆
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T8679Epidermal Growth FactorEpidermal Growth Factor
Epidermal Growth Factor binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. It is approved for the treatment of diabetic foot ulcers.
价 格:¥电议型 号:T8679产 地:中国大陆