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T18318MC-Val-Ala-PAB-PNP;化合物MC-Val-Ala-PAB-PNPinhibit|||ADC Linkers|||Inhibitor|||MC Val Ala PAB PNP|||Ant
MC-Val-Ala-PAB-PNP is a cleavable ADC linker. MC-Val-Ala-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18318产 地:中国大陆
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T18231MAC glucuronide linker-2;化合物 T18231MAC glucuronide linker-2
MAC glucuronide linker-2 is an ADC linker employed in the synthesis of ADCs, offering cleavability [1].
价 格:¥电议型 号:T18231产 地:中国大陆
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T18230MAC glucuronide linker-1;化合物 T18230MAC glucuronide linker-1
MAC glucuronide linker-1 is a nonclaevable ADC linker for antibody-drug-conjugations (ADCs).
价 格:¥电议型 号:T18230产 地:中国大陆
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T18063Lenalidomide-acetylene-C5-COOH;化合物 T18063Cereblon ligand-linker Conjugate;Cereblon ligand-linker Con
Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) serves as a Lenalidomide-based Cereblon ligand that facilitates the recruitment of the CRBN protein. This compound can be connected to the protein´s ligand through a linker, resulting in the formation of PROTAC[1].
价 格:¥电议型 号:T18063产 地:中国大陆
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T18059K-Ras ligand-Linker Conjugate 6;化合物 T18059K-Ras ligand-Linker Conjugate 6
K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for K-Ras recruiting moiety and a PROTAC linker. This compound can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker Conjugate 6 is particularly useful in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
价 格:¥电议型 号:T18059产 地:中国大陆
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T18058K-Ras ligand-Linker Conjugate 5;化合物 T18058K-Ras ligand-Linker Conjugate 5
K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The K-Ras ligand-Linker Conjugate 5 plays a crucial role in the synthesis of PROTAC K-Ras Degrader-1, a highly potent K-Ras degrader. In SW1573 cells, this degrader exhibits an impressive degradation efficacy of ≥70% [1].
价 格:¥电议型 号:T18058产 地:中国大陆
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T18057K-Ras ligand-Linker Conjugate 4;化合物 T18057K-Ras ligand-Linker Conjugate 4
K-Ras ligand-Linker Conjugate 4 is a chemical compound that combines a ligand for K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The compound has the potential to be used in the synthesis of PROTAC K-Ras Degrader-1, a powerful degrader of K-Ras that has been shown to exhibit a degradation efficacy of ≥70% in SW1573 cells[1].
价 格:¥电议型 号:T18057产 地:中国大陆
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T18056K-Ras ligand-Linker Conjugate 3;化合物 T18056K-Ras ligand-Linker Conjugate 3
K-Ras ligand-Linker Conjugate 3 (Compound 001371) is a chemical compound that consists of a ligand for K-Ras recruiting moiety and a PROTAC linker, responsible for recruiting E3 ligases (e.g., VHL, CRBN, MDM2, and IAP). This compound is essential in the synthesis of PROTAC K-Ras Degrader-1, a potent PROTAC K-Ras degrader that demonstrates a degradation efficacy of ≥70% in SW1573 cells[1].
价 格:¥电议型 号:T18056产 地:中国大陆
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T18055K-Ras ligand-Linker Conjugate 2;化合物 T18055K-Ras ligand-Linker Conjugate 2
K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesis of PROTAC K-Ras Degrader-1, which is a highly effective PROTAC K-Ras degrader with a degradation efficacy of ≥70% in SW1573 cells[1].
价 格:¥电议型 号:T18055产 地:中国大陆
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T18054K-Ras ligand-Linker Conjugate 1;化合物 T18054K-Ras ligand-Linker Conjugate 1
K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
价 格:¥电议型 号:T18054产 地:中国大陆
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T17943FAK ligand-Linker Conjugate 1;化合物 T17943FAK ligand-Linker Conjugate 1
FAK ligand-Linker Conjugate 1 is a chemical compound designed to facilitate PROTAC-mediated protein degradation. This compound consists of a ligand specifically targeting FAK and a PROTAC linker module, which acts as a recruitment agent for E3 ligases including VHL, CRBN, MDM2, and IAP[1].
价 格:¥电议型 号:T17943产 地:中国大陆
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T17941ERRα Ligand-Linker Conjugates 1;化合物 T17941ERRα Ligand-Linker Conjugates 1
ERRα Ligand-Linker Conjugates 1 refers to a chemical compound that consists of a ligand targeting estrogen-related receptor alpha (ERRα), and a PROTAC linker that facilitates the recruitment of E3 ligases MDM2. It finds utility in the synthesis of a range of PROTACs, including one known as PROTAC ERRalpha Degrader-1. With its capability to induce degradation of ERRα, PROTAC ERRalpha Degrader-1 functions as an ERRα degrader[1].
价 格:¥电议型 号:T17941产 地:中国大陆
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T17928Lenalidomide-C5-NH2;化合物 T17928E3 ligase Ligand-Linker Conjugates 31|||Cereblon Ligand-Linker Conjuga
Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1].
价 格:¥电议型 号:T17928产 地:中国大陆
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T17926(S,R,S)-AHPC-PEG6-C4-Cl;化合物 T17926VHL Ligand-Linker Conjugates 10|||E3 ligase Ligand-Linker Conjugat
(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
价 格:¥电议型 号:T17926产 地:中国大陆
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T17925(S,R,S)-AHPC-PEG2-NH2化合物(S,R,S)-AHPC-PEG2-NH2VH032-PEG2-NH2|||VHL Ligand-Linker Conjugates 3|||E3 li
(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
价 格:¥电议型 号:T17925产 地:中国大陆
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T17923(S,R,S)-AHPC-PEG3-NH2;化合物 T17923E3 ligase Ligand-Linker Conjugates 5 Free Base|||VH032-PEG3-NH2|||VH
(S,R,S)-AHPC-PEG3-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, incorporating the (S,R,S)-AHPC VHL ligand and a 3-unit PEG linker, which are utilized in PROTAC technology.
价 格:¥电议型 号:T17923产 地:中国大陆
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T17922(S,R,S)-AHPC-PEG3-NH2 hydrochloride;化合物T17922VHL Ligand-Linker Conjugates 1 hydrochloride|||E3 ligas
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC-based VHL ligand and 3-unit PEG linker.
价 格:¥电议型 号:T17922产 地:中国大陆
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T17921(S,R,S)-AHPC-PEG4-N3;化合物T17921VH032-PEG4-N3|||VHL Ligand-Linker Conjugates 5|||E3 ligase Ligand-Link
(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both commonly employed in PROTAC technology.
价 格:¥电议型 号:T17921产 地:中国大陆
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T17920(S,R,S)-AHPC-PEG1-N3;化合物(S,R,S)-AHPC-PEG1-N3VHL Ligand-Linker Conjugates 9|||VH032-PEG1-N3|||E3 liga
(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG1-N3 incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17920产 地:中国大陆
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T17919Thalidomide-O-amido-C6-NH2 TFA;化合物T17919E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate|||Cer
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
价 格:¥电议型 号:T17919产 地:中国大陆