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T77028Gosuranemab;化合物 GosuranemabGosuranemab
Gosuranemab (BMS-986168), a humanized IgG4 anti-tau monoclonal antibody, specifically targets human N-terminal tau residues 15-22. It holds potential for Alzheimer’s disease (AD) research [1] [2].
价 格:¥电议型 号:T77028产 地:中国大陆
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T76692Mosunetuzumab;莫妥珠单抗BTCT-4465A;BTCT-4465A
Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to study relapsed or refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL) and refractory follicular lymphoma.
价 格:¥电议型 号:T76692产 地:中国大陆
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T75885PKC β pseudosubstrate TFA;化合物 PKC β pseudosubstrate TFAPKC β pseudosubstrate TFA
PKC β pseudosubstrate TFA is a selective cell-permeable inhibitor of PKC [1] .
价 格:¥电议型 号:T75885产 地:中国大陆
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T7523Guanidinosuccinic acid胍基琥珀酸2-胍基琥珀酸|||胍基琥珀酸
Guanidinosuccinic acid (GSA) has been identified as a uremic toxin, is a nitrogenous metabolite isolated in excess from serum and urine.
价 格:¥电议型 号:T7523产 地:中国大陆
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T74598Zosurabalpin;化合物 ZosurabalpinZosurabalpin
Zosurabalpin is an antibacterial agent [1] .
价 格:¥电议型 号:T74598产 地:中国大陆
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T74074OSu-Glu-VC-PAB-MMAD;化合物 OSu-Glu-VC-PAB-MMADOSu-Glu-VC-PAB-MMAD
OSu-Glu-VC-PAB-MMAD is an agent-linker conjugate designed for antibody-drug conjugates (ADCs) featuring potent antitumor activity. It incorporates MMAD, a powerful tubulin inhibitor, connected through the cleavable ADC linker OSu-Glu-VC-PAB, facilitating targeted cancer therapy.
价 格:¥电议型 号:T74074产 地:中国大陆
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T73919Adenylosuccinic acid tetraammonium;化合物 Adenylosuccinic acid tetraammoniumAdenylosuccinic acid tetraa
Adenylosuccinic Acid Tetraammonium (also known as Adenylosuccinate or Aspartyl Adenylate) is an orally active compound that functions as a purine ribonucleoside monophosphate and is involved in nucleotide cycle metabolism. It can be transformed into fumaric acid via adenylosuccinate lyase action. This compound holds potential for research in Duchenne Muscular Dystrophy (DMD) [1].
价 格:¥电议型 号:T73919产 地:中国大陆
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T72010Dibenzosuberenol;化合物 DibenzosuberenolDibenzosuberenol
Dibenzosuberenol is a reactant involved in oxidation with tert-butylhydroperoxide in water for synthesis of carboxylic acids and ketones; Synthesis of tachykinin neurokinin-1 receptor antagonists; Pauson-Khand reaction mechanism studies; Mapping the active site of aziridination catalysts.
价 格:¥电议型 号:T72010产 地:中国大陆
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T7129(E/Z)-Necrosulfonamide化合物 (E/Z)-NecrosulfonamideN-[4-[[(3-甲氧基吡嗪基)氨基]磺酰基]苯基]-3-(5-硝基-2-噻吩基)-2-丙烯酰胺
(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.
价 格:¥电议型 号:T7129产 地:中国大陆
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T71106Cotosudil 2HCl;化合物 Cotosudil 2HClCotosudil 2HCl
Cotosudil 2HCl is the salt form of Cotosudil Free Base, a Rho-associated (ROCK) kinase inhibitor.
价 格:¥电议型 号:T71106产 地:中国大陆
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T71051OSU-53;化合物 OSU-53OSU-53
OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.
价 格:¥电议型 号:T71051产 地:中国大陆
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T70735Verosudil hydrochloride;化合物 Verosudil hydrochlorideVerosudil hydrochloride
Verosudil, also known as AR-12286, is a potent and selective Rho kinase inhibitor. AR-12286 was well tolerated and provided statistically significant reduction in IOP (intraocular pressure) in patients with XFS (exfoliation syndrome) and OHT (ocular hypertension) or XFG (exfoliative glaucoma). This drug may represent an additional therapeutic paradigm for the treatment of XFG.
价 格:¥电议型 号:T70735产 地:中国大陆
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T7059α-Dihydroartemisinin;α-双氢青蒿素α-Artenimol|||α-Dihydroqinghaosu;α-Artenimol|||α-Dihydroqinghaosu
α-Dihydroartemisinin (α-Dihydroqinghaosu) is an intermediate of artemisinin-based antimalarial compounds with good antimalarial and anticancer activity, and can be used in the study of lupus erythematosus.
价 格:¥电议型 号:T7059产 地:中国大陆
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T6967RHPS4;化合物RHPS4RHPS 4 methosulfate|||NSC714187;RHPS 4 methosulfate|||NSC714187
RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.
价 格:¥电议型 号:T6967产 地:中国大陆
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T69178Rosuvastatin lactone;化合物 Rosuvastatin lactoneRosuvastatin lactone
Rosuvastatin lactone is the lactone form of the HMG-CoA reductase inhibitor rosuvastatin. It is found in vivo following rosuvastatin administration. Rosuvastatin lactone is an inhibitor of the cytochrome P450 (CYP) isoforms CYP2C9.1 and CYP2C9.3 (IC50s = 8.52 and 4.1 ?M, respectively).
价 格:¥电议型 号:T69178产 地:中国大陆
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T6904Necrosulfonamide;化合物(E)-Necrosulfonamide(E)-Necrosulfonamide;(E)-Necrosulfonamide
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Binds and inhibits gasdermin D. Inhibits pyroptosis.
价 格:¥电议型 号:T6904产 地:中国大陆
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T6867Belumosudil化合物KD025KD025|||Rezurock|||ROCK inhibitor|||SLx-2119
Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).
价 格:¥电议型 号:T6867产 地:中国大陆
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T68095Losulazine;洛硫嗪Losulazine
Losulazine is a new antihypertensive in man. Its exact mechanism of action has not been defined, but its hypotensive activity depends on the presence of an intact, functional sympathetic nervous system.
价 格:¥电议型 号:T68095产 地:中国大陆
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T6781Benzenesulfonamide;苯磺酰胺Benzenesulphonamide|||Phenyl sulfonamide|||Benzosulfonamide;Benzenesulphonami
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.
价 格:¥电议型 号:T6781产 地:中国大陆
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T669234-Chloro-3-(chlorosulfonyl)benzoic acid;化合物 4-Chloro-3-(chlorosulfonyl)benzoic acid4-Chloro-3-(chlor
4-Chloro-3-(chlorosulfonyl)benzoic acid is a useful organic compound for research related to life sciences. The catalog number is T66923 and the CAS number is 2494-79-3.
价 格:¥电议型 号:T66923产 地:中国大陆