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TQ0159U-73343U-73343,Inhibitor,U73343,Phospholipase,inhibit
U 73343 is an inactive analog of U 73122 and can be used as a negative control. It dose-dependently inhibits acid secretion irrespective of the stimulant. It is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50 of 1-2.1 μM for PLC.
价 格:¥电议型 号:TQ0159产 地:中国大陆
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TN6745PALATINOSEPALATINOSE
PALATINOSE is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose。 PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for sucrose as a sweetener.
价 格:¥电议型 号:TN6745产 地:中国大陆
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T6446ClevudineOrthopoxvirus,half-life,nucleoside,DNA/RNA Synthesis,analog,Inhibitor,polymerase,Hepatitis
Clevudine is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DN
价 格:¥电议型 号:T6446产 地:中国大陆
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T70421,5-IsoquinolinediolPARP,diabetic,1188540,oxidative,retinopathy,1,5 Isoquinolinediol,stress,inhibit,
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
价 格:¥电议型 号:T7042产 地:中国大陆
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T7558CID-1067700ML282,competitively,CID1067700,brain,Rab7,ML 282,GTPase,Ras,machinery,Ras-related,CID-106
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).
价 格:¥电议型 号:T7558产 地:中国大陆
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T6561Laquinimodinhibit,multiple sclerosis,relapsing remitting,carboxamide,Nuclear factor-kappaB,Apoptosis
Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格:¥电议型 号:T6561产 地:中国大陆
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T14969CINPA1
CINPA1 is a selective inhibitor of constitutive androstane receptor (CAR) with an IC50 of 70 nM for CAR-mediated transcription. CINPA1 can be used in studies about CAR function.
价 格:¥电议型 号:T14969产 地:中国大陆
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T6S0840EngeletinNuclear factor-kappaB,Engeletin,inhibit,NF-κB,Inhibitor,Nuclear factor-κB
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
价 格:¥电议型 号:T6S0840产 地:中国大陆
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T7070Nomifensine maleateDopamine Receptor,inhibit,Inhibitor,Nomifensine maleate,Nomifensine
Nomifensine maleate is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.
价 格:¥电议型 号:T7070产 地:中国大陆
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T1636LParoxetine hydrochloride hemihydrate
Paroxetine hydrochloride hemihydrate is an effective and selective serotonin reuptake inhibitor (SSRI).
价 格:¥电议型 号:T1636L产 地:中国大陆
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T64337PF-04745637PF04745637,Inhibitor,bowel,TRPA1,disease,inhibit,respiratory,PF-04745637,Transient recept
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
价 格:¥电议型 号:T64337产 地:中国大陆
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T41277PACMA 31bond,tumor,ovarian,athymic,PACMA31,inhibit,toxicity,colony,PACMA-31,mice,PACMA 31,oral,Inhib
PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.
价 格:¥电议型 号:T41277产 地:中国大陆
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T7774A2793A2793,inhibit,Inhibitor,A-2793,TALK-1,TRESK,pain,KcsA,TASK-1,A 2793,Potassium Channel
A2793 is a chemical compound
价 格:¥电议型 号:T7774产 地:中国大陆
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T6726VU0361737Parkinson’s,inhibit,ML128,neuroprotective,Metabotropic glutamate receptors,VU0361737,Inhibi
VU 0361737 is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity at mGlu5 and mGlu8 receptors, and is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.
价 格:¥电议型 号:T6726产 地:中国大陆
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T7502LPF 05089771Na+ channels,diabetic,inhibit,Inhibitor,neuropathy,Sodium Channel,Na channels,TTX-R,PF 05
PF-05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.
价 格:¥电议型 号:T7502L产 地:中国大陆
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TN6791Palvanilanti-inflammation,inhibit,HEK-293,Inhibitor,anti-nociceptive,Palvanil
Palvanil is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and reduces visceral pain.
价 格:¥电议型 号:TN6791产 地:中国大陆
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T6481DroxinostatHDAC3,hepatocellular carcinoma (HCC),Droxinostat,NS-41080,Apoptosis,Histone deacetylases,
Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
价 格:¥电议型 号:T6481产 地:中国大陆
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T9218AndrograpaninInhibitor,chemotaxis,p38 MAPK,leukocyte,SDF-1α,Andrograpanin,PBL,inhibit,Jurkat,anti-in
Andrograpanin is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
价 格:¥电议型 号:T9218产 地:中国大陆
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T6S0119DauricineNuclear factor-κB,Inhibitor,inhibit,Dauricine,Nuclear factor-kappaB,Apoptosis,NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profil
价 格:¥电议型 号:T6S0119产 地:中国大陆