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T7741DS-1001b;化合物DS-1001bDS-1001b
DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
价 格:¥电议型 号:T7741产 地:中国大陆
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T7609ARS-1620;化合物ARS-1620ARS-1620
ARS-1620 is a covalent inhibitor of K-RASG12C.
价 格:¥电议型 号:T7609产 地:中国大陆
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T75605(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid;化合物 (2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-2
´(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid, a saponin isolated from Rubus ellipticus var. obcordatus, inhibits α-Glucosidase with an IC 50 of 1.68 mM [1].´
价 格:¥电议型 号:T75605产 地:中国大陆
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T75562Ganoderic acid GS-1;化合物 Ganoderic acid GS-1Ganoderic acid GS-1
Ganoderic acid GS-1, an extensively oxygenated lanostane-type triterpenoid, exhibits anti-HIV-1 protease activities, displaying an IC50 value of 58 μM [1].
价 格:¥电议型 号:T75562产 地:中国大陆
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T7519RS-127445 hydrochloride;化合物RS 127445RS 127445|||MT 500;4-(4-氟-1-萘基)-6-(1-甲基乙基)-2-嘧啶胺盐酸盐|||RS 127445|
RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).
价 格:¥电议型 号:T7519产 地:中国大陆
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T7512BMS-191011;化合物BMS-191011BMS-A;BMS-A
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
价 格:¥电议型 号:T7512产 地:中国大陆
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T7416WS-12;化合物WS-12WS-12
WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)
价 格:¥电议型 号:T7416产 地:中国大陆
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T74029cis-11-Methyl-2-dodecenoic acid;化合物 cis-11-Methyl-2-dodecenoic acidcis-11-Methyl-2-dodecenoic acid
Cis-11-Methyl-2-dodecenoic acid functions as a quorum sensing (QS) signal and a diffusion signaling factor (DSF) within extracellular microbial and fungal communication systems. It plays a pivotal role in regulating virulence and biofilm formation among diverse bacterial pathogens [1].
价 格:¥电议型 号:T74029产 地:中国大陆
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T7309TAS-103 dihydrochloride;化合物TAS-103 (dihydrochloride)TAS-103 (dihydrochloride)|||BMS-247615 dihydroch
TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.
价 格:¥电议型 号:T7309产 地:中国大陆
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T721446-trans-12-epi-Leukotriene B4;化合物 6-trans-12-epi-Leukotriene B46-trans-12-epi-Leukotriene B4
6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent.
价 格:¥电议型 号:T72144产 地:中国大陆
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T7197LFadrozole HCl hydrate;化合物 T7197LFadrozole|||CGS-16949A|||Fadrozole hydrochloride hemihydrate|||CGS16
Fadrozole is a selective inhibitor of aromatase. It also effective in the treatment of estrogen-dependent diseases including breast cancer.
价 格:¥电议型 号:T7197L产 地:中国大陆
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T71951AS-1940477 hydrobromide;化合物 AS-1940477 hydrobromideAS-1940477 hydrobromide
AS-1940477 hydrobromide is a p38 mitogen-activated protein kinase (MAPK) inhibitor.
价 格:¥电议型 号:T71951产 地:中国大陆
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T71577KOS-1584;化合物 KOS-1584KOS-1584
KOS-1584 is a second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to first-generation epothilones, this agent exhibits greater safety and efficacy with an enhanced pharmaceutical profile, including enhanced water solubility and tumor penetration,
价 格:¥电议型 号:T71577产 地:中国大陆
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T71501GBS-149;化合物 GBS-149GBS-149
GBS-149 is a novel non-toxic and mammalian-specific LINE-1 inhibitor.
价 格:¥电议型 号:T71501产 地:中国大陆
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T71251DS-1558;化合物 DS-1558DS-1558
DS-1558 is a potent and orally available GPR40 agonist.DS-1558 was found to have potent glucose lowering effects during an oral glucose tolerance test in ZDF rats. DS-1558 significantly and dose-dependently improved hyperglycemia and increased insulin secretion during the oral glucose tolerance test in Zucker fatty rats, the model of insulin resistance and glucose intolerance. DS-1558 not only increased the glucose-stimulated insulin secretion by GLP-1 but also potentiated the maximum insulinog
价 格:¥电议型 号:T71251产 地:中国大陆
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T71218AEZS-112;化合物 AEZS-112AEZS-112
AEZS-112, also known as ZEN012, is an orally active small mol. anti-cancer drug which inhibits the polymn. of tubulin at low micromolar concns. AEZS 112 dose-dependently increased non-vital hypodiploid cells and the cytotoxic effect was least pronounced in G2 phase of the cell cycle, indicating cell death during mitosis, as detd. by FACS anal. AEZS 112 showed anti-tumor activity in human ovarian and endometrial cancer cell lines at low micromolar concns., which could not be abrogated by caspase
价 格:¥电议型 号:T71218产 地:中国大陆
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T71147PBS-1086;化合物 PBS-1086PBS-1086
PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines.
价 格:¥电议型 号:T71147产 地:中国大陆
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T7108Omberacetam;化合物NoopeptSGS-111|||Noopept|||GVS-111;SGS-111|||Noopept|||GVS-111
Omberacetam (Noopept) is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compounds.
价 格:¥电议型 号:T7108产 地:中国大陆
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T70776AS-1669058 free base;化合物 AS-1669058 free baseAS-1669058 free base
AS-1669058 free base is a G-protein-coupled receptor 119 (GPR119) agonist used to as new drug to treat type 2 diabetes.
价 格:¥电议型 号:T70776产 地:中国大陆