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T753404-Methylumbelliferyl phosphate disodium;化合物 4-Methylumbelliferyl phosphate disodium4-Methylumbellife
4-Methylumbelliferyl phosphate disodium (4-MUP), an anionic organophosphate, serves as a fluorogenic substrate for acid and alkaline phosphatases. Additionally, this compound acts as a simulant for nerve agents [1] [2] [3].
价 格:¥电议型 号:T75340产 地:中国大陆
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T74948LSARS-CoV-2-IN-30 disodium;化合物 SARS-CoV-2-IN-30 disodiumSARS-CoV-2-IN-30 disodium
SARS-CoV-2-IN-30 disodium, a benzene-system-based two-armed diphosphate ester featuring molecular tweezers, demonstrates antiviral efficacy, with IC50 values of 0.6 μM against SARS-CoV-2 and 6.9 μM for spike pseudoparticle transduction, respectively. Additionally, it disrupts liposomal membranes, evidenced by an EC50 of 6.9 μM [1].
价 格:¥电议型 号:T74948L产 地:中国大陆
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T74947LSARS-CoV-2-IN-29 disodium;化合物 SARS-CoV-2-IN-29 disodiumSARS-CoV-2-IN-29 disodium
SARS-CoV-2-IN-29 disodium, a diphosphate ester featuring a benzene system and molecular tweezers architecture, demonstrates antiviral efficacy by targeting SARS-CoV-2 with half-maximal inhibitory concentrations (IC50s) of 1.5 μM for virus activity and 1.6 μM for spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes, evidenced by a half-maximal effective concentration (EC50) of 3.0 μM [1].
价 格:¥电议型 号:T74947L产 地:中国大陆
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T74946LSARS-CoV-2-IN-28 disodium;化合物 SARS-CoV-2-IN-28 disodiumSARS-CoV-2-IN-28 disodium
SARS-CoV-2-IN-28 disodium, a diphosphate ester featuring a C7 alkyl chain and extended-length molecular tweezers, demonstrates antiviral efficacy by showing IC50 values of 0.4 μM and 1.0 μM against SARS-CoV-2 activity and spike pseudoparticle transduction, respectively. Additionally, it disrupts liposomal membranes with an EC50 of 4.4 μM [1].
价 格:¥电议型 号:T74946L产 地:中国大陆
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T74945LSARS-CoV-2-IN-27 disodium;化合物 SARS-CoV-2-IN-27 disodiumSARS-CoV-2-IN-27 disodium
SARS-CoV-2-IN-27 disodium, a diphosphate ester featuring a C6 alkyl chain and molecular tweezers of extended length, demonstrates antiviral efficacy by achieving IC50 values of 1.0 μM against SARS-CoV-2 activity and 1.7 μM for spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes, displaying an EC50 value of 6.5 μM [1].
价 格:¥电议型 号:T74945L产 地:中国大陆
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T74944LSARS-CoV-2-IN-23 disodium;化合物 SARS-CoV-2-IN-23 disodiumSARS-CoV-2-IN-23 disodium
SARS-CoV-2-IN-23 disodium, a medium-length molecular tweezer and two-armed diphosphate ester, demonstrates antiviral properties by inhibiting SARS-CoV-2 activity and spike pseudoparticle transduction with IC50 values of 8.2 μM and 2.6 μM, respectively. Additionally, it disrupts liposomal membranes with an EC50 of 4.4 μM [1].
价 格:¥电议型 号:T74944L产 地:中国大陆
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T74943LSARS-CoV-2-IN-25 disodium;化合物 SARS-CoV-2-IN-25 disodiumSARS-CoV-2-IN-25 disodium
SARS-CoV-2-IN-25 (Compound CP026) disodium, a potent inhibitor of SARS-CoV-2 spike pseudoparticle transduction, demonstrates significant efficacy with an IC50 value of 1.6 μM. Additionally, it effectively inhibits enveloped viruses and liposomes, showcasing its broad-spectrum antiviral potential.
价 格:¥电议型 号:T74943L产 地:中国大陆
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T74549N-Acetyl-α-D-glucosamine 1-phosphate disodium;化合物 N-Acetyl-α-D-glucosamine 1-phosphate disodiumN-Ace
N-Acetyl-α-D-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, plays a crucial role as an intermediate in the biosynthesis of N-linked glycoproteins. Additionally, it serves as a metabolic precursor for the synthesis of bacterial cell-wall components, particularly teichoic acid and murein [1].
价 格:¥电议型 号:T74549产 地:中国大陆
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T74160UDP-glucosamine disodium;化合物 UDP-glucosamine disodiumUDP-glucosamine disodium
UDP-glucosamine (UDP-GlcNAc) disodium serves as a substrate for O-GlcNAc transferase, facilitating the addition of O-GlcNAc to proteins, while its removal is catalyzed by O-GlcNAcase. This compound also represents the culmination of the hexosamine biosynthesis pathway, mainly regulated by the enzyme glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT) [1].
价 格:¥电议型 号:T74160产 地:中国大陆
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T74042GDP-L-fucose disodium;化合物 GDP-L-fucose disodiumGDP-L-fucose disodium
GDP-L-fucose disodium, a nucleotide sugar, serves as a crucial substrate for fucose oligosaccharides biosynthesis by providing the fucose moiety. Its formation follows two metabolic pathways: the primary de novo pathway and the secondary remedial pathway [1].
价 格:¥电议型 号:T74042产 地:中国大陆
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T73938IACS-8803 disodium;化合物 IACS-8803 disodiumIACS-8803 disodium
IACS-8803 Disodium, a potent cyclic dinucleotide STING agonist, exhibits strong systemic antitumor efficacy [1].
价 格:¥电议型 号:T73938产 地:中国大陆
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T73925α-D-Glucose-1-phosphate disodium hydrate;化合物 α-D-Glucose-1-phosphate disodium hydrateα-D-Glucose-1-p
α-D-Glucose-1-phosphate disodium hydrate serves multiple roles in medical and biochemical applications, including as a precursor in the synthesis of glucuronic acid, a cytostatic compound crucial for cardiopathic therapy, an antibiotic, an immunosuppressive agent, and a component in circulatory system therapy [1].
价 格:¥电议型 号:T73925产 地:中国大陆
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T73873c-di-AMP disodium;化合物 c-di-AMP disodiumc-di-AMP disodium
Cyclic diadenylate (c-di-AMP) sodium functions as a STING agonist by binding to the STING transmembrane protein, thus activating the TBK3-IRF3 signaling pathway. This activation prompts the production of type I IFN and TNF. Additionally, c-di-AMP sodium serves as a bacterial second messenger in Gram-positive bacteria, where it plays crucial roles in regulating cell growth, survival, and virulence, as well as the host immune response. It also acts as a potent mucosal adjuvant by stimulating both
价 格:¥电议型 号:T73873产 地:中国大陆
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T73809UDP-GalNAc disodium;化合物 UDP-GalNAc disodiumUDP-GalNAc disodium
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium, a sugar nucleotide, serves as a substrate for EpsC115, an exopolymeric substances (EPS) N-terminal deletion mutant characterized by the absence of residues 1-115. Additionally, UDP-GalNAc acts as the donor substrate for numerous N-acetylgalactosaminyltransferases. These enzymes facilitate the transfer of GalNAc from the nucleotide sugar to various saccharide or peptide acceptors [1].
价 格:¥电议型 号:T73809产 地:中国大陆
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T73732D-Fructose 1-phosphate disodium;化合物 D-Fructose 1-phosphate disodiumD-Fructose 1-phosphate disodium
D-Fructose 1-phosphate disodium salt, a derivative of fructose, serves as a crucial intermediate in glucose metabolism.
价 格:¥电议型 号:T73732产 地:中国大陆
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T7373110-Formyltetrahydrofolic acid disodium;化合物 10-Formyltetrahydrofolic acid disodium10-Formyltetrahydro
10-Formyltetrahydrofolic acid disodium, a derivative of tetrahydrofolic acid, serves as a formyl group donor in anabolic processes. It functions as a substrate for formyltransferase reactions, playing a crucial role in purine biosynthesis [1].
价 格:¥电议型 号:T73731产 地:中国大陆
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T73628PSB-12379 disodium;化合物 PSB-12379 disodiumPSB-12379 disodium
PSB-12379 disodium is a nucleotide analogue acting as a potent inhibitor of Ecto-5´-Nucleotidase (CD73), demonstrating inhibitory constants (Ki) of 9.03 nM in rats and 2.21 nM in humans [1] [2].
价 格:¥电议型 号:T73628产 地:中国大陆
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T72811E7766 disodium;化合物 E7766 disodiumE7766 disodium
E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.
价 格:¥电议型 号:T72811产 地:中国大陆
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T72516IACS-8779 disodium;化合物 IACS-8779 disodiumIACS-8779 disodium
IACS-8779 disodium, a highly potent STING (stimulator of interferon genes) agonist, demonstrates robust activation of the STING pathway in vitro, along with superior systemic antitumor efficacy. This compound shows a significant anti-tumor response in the B16 murine melanoma model, indicating its potential for effective cancer therapy.
价 格:¥电议型 号:T72516产 地:中国大陆
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T72482Dazostinag disodium;Dazostinag 二钠盐TAK-676;TAK-676
Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendritic cells, natural killer cells, and T cells.
价 格:¥电议型 号:T72482产 地:中国大陆