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T405896-O-β-D-Galactopyranosyl-D-galactose；6-O-β-D-Galactopyranosyl-D-galactose6-O-β-D-Galactopyranosyl-D-
6-O-beta-D-Galactopyranosyl-D-galactose, a disaccharide, is a constituent of the polysaccharide backbone characterized by beta-(1→6) glycoside linkages, with a side chain attached to the primary chain through a beta-(1→3) bond.
价 格：￥电议型 号：T40589产 地：中国大陆
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T40435Chlorin e6 trimethyl ester二氢卟吩 e6 三甲酯二氢卟吩 e6 三甲酯
Chlorin e6 trimethyl ester, a derivative of methyl pheophorbide-a, is an effective photosensitizer for photodynamic therapy (PDT).
价 格：￥电议型 号：T40435产 地：中国大陆
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T404346-Azido-hexylamine；6-Azido-hexylamine6-Azido-hexylamine
6-Azido-hexylamine is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T40434产 地：中国大陆
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T401786,7-Dimethyl-8-ribityllumazine；6,7-Dimethyl-8-ribityllumazine6,7-Dimethyl-8-ribityllumazine
6,7-Dimethyl-8-ribityllumazine is a biosynthetic precursor of Riboflavin (RBF). It serves as a noncovalently bound fluorophore of Lumazine protein (LumP), an accessory protein that exhibits fluorescence.
价 格：￥电议型 号：T40178产 地：中国大陆
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T3987Lotamilast；化合物LotamilastE6005|||RVT-501；E6005|||RVT-501
Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis.
价 格：￥电议型 号：T3987产 地：中国大陆
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T39812(E/Z)-E64FC26(E/Z)-E64FC26(E/Z)-E64FC26
(E/Z)-E64FC26 is a mixture complex comprising E-E64FC26 and Z-E64FC26. E-E64FC26 is a highly potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50 values of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6, respectively. Furthermore, E64FC26 demonstrates anti-myeloma activity.
价 格：￥电议型 号：T39812产 地：中国大陆
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T38774E67-2E67-2E67-2
E67-2, a derivative of E67, is a low-toxicity, selective inhibitor of the KIAA1718 Jumonji domain. It has an IC 50 value of 3.4 μM. E67-2 specifically inhibits the Jumonji demethylase for histone H3 lysine 9 (H3K9) and histone H3 lysine 4 (H3K4) demethylase.
价 格：￥电议型 号：T38774产 地：中国大陆
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T387086-Acetyldepheline；6-Acetyldepheline6-Acetyldepheline
6-Acetyldepheline, a natural alkaloid, can be isolated from Delphinium tatsienense.
价 格：￥电议型 号：T38708产 地：中国大陆
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T381876-Aminophenanthridine；6-Aminophenanthridine6-Aminophenanthridine
6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz . 6-Aminophenanthridine (300 μM) inhibits protein folding activity of the ribosome (PFAR) by directly competing with protein substrates for the active site and decreases the yield of refolded protein without affecting the refolding rate. It prevents progressive w
价 格：￥电议型 号：T38187产 地：中国大陆
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T381866-Amino-8-trifluoromethylphenanthridine；6-Amino-8-trifluoromethylphenanthridine6-Amino-8-trifluorome
6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine . It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM. 6A-8tFP directly competes with protein substrates for the ribosomal active site.
价 格：￥电议型 号：T38186产 地：中国大陆
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T373616β-hydroxy Dexamethasone；6β-hydroxy Dexamethasone6β-hydroxy Dexamethasone
6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans., The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing
价 格：￥电议型 号：T37361产 地：中国大陆
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T373066-hydroxy Chlorzoxazone；6-hydroxy Chlorzoxazone6-hydroxy Chlorzoxazone|||NSC 24955；6-hydroxy Chlorzo
6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone. [1] It is formed by metabolism of chlorzoxazone by the cytochrome P450 (CYP) isoform CYP2E1 in human hepatic microsomes.
价 格：￥电议型 号：T37306产 地：中国大陆
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T370656-Chloro-2-fluoropurine；6-Chloro-2-fluoropurine6-Chloro-2-fluoropurine
6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2
价 格：￥电议型 号：T37065产 地：中国大陆
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T370646β-hydroxy Eplerenone；6β-hydroxy Eplerenone6β-hydroxy Eplerenone
6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.
价 格：￥电议型 号：T37064产 地：中国大陆
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T368726,7-Dihydro-5H-quinolin-8-one；6,7-Dihydro-5H-quinolin-8-one6,7-Dihydro-5H-quinolin-8-one
6,7-Dihydro-5H-quinolin-8-one is a synthetic intermediate.1,2It has been used in the synthesis of tetrahydropyridoazepinones and thiosemicarbazones with anticancer activity.
价 格：￥电议型 号：T36872产 地：中国大陆
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T3678Entrectinib；恩曲替尼RXDX-101|||NMS-E628；RXDX-101|||恩曲替尼|||NMS-E628
Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectinib blocks proliferation of ALK-dependent cell lines, including those with C1156Y or L1196M resistance mutations, and inhibits ALK‐dependent signaling. It has been shown to inhibit the growth of a non-small cell lung Y cell line bearing an EML4-ALK rearrangement. In mice bearing va
价 格：￥电议型 号：T3678产 地：中国大陆
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T36651Anti-MERS-2E6 mAb；Anti-MERS-2E6 mAbAnti-MERS-2E6 mAb；Anti-MERS-2E6 mAb
Anti-MERS-2E6 mAb (MERS-2E6), a human IgG1 neutralizing antibody, is expressed in CHO cells. It effectively competes with the virus Spike protein for binding to the CD26 receptor, consequently inhibiting viral invasion into host cells.
价 格：￥电议型 号：T36651产 地：中国大陆
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T36466Chlorin E6；二氢卟吩E6Ce6|||Chlorin e6|||CE6；Ce6|||Chlorin e6|||CE6
Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation. In a mouse model of implanted fibrosarcoma, Chlorin E6 (2.5-10 mg/kg, i.v., 50-200 J/cm2 irradiation) resulted in complete tumor disappearance after varying degrees of irradiation. Agents including Chlorin E6 were tested in a Phase I clinical study in patients with early superficial squamous cell carcinoma of bronchial origin with favorable results (40 mg/m2, IV, 100 J/cm2 l
价 格：￥电议型 号：T36466产 地：中国大陆
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T359756,9-Dichloro-1,2,3,4-tetrahydroacridine；6,9-Dichloro-1,2,3,4-tetrahydroacridine6,9-Dichloro-1,2,3,4-
6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3
价 格：￥电议型 号：T35975产 地：中国大陆
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T354856-Prenylindole；6-Prenylindole6-Prenylindole
6-Prenylindole is a bacterial metabolite that has been found in Streptomyces and has antifungal and antimalarial properties.1 It is active against A. brassicicola strain TP-F0423 and F. oxysporum f. sp. tulipae TU-4-2 (15 and 30 μg/disc in the paper disc assay), and also drug-resistant P. falciparum strain K1 (IC50 = 21 μg/ml).2
价 格：￥电议型 号：T35485产 地：中国大陆
