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T13433β-Endorphin, humanβ-Endorphin, human
β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus,and is an agonist of opioid receptor.
价 格：￥电议型 号：T13433产 地：美洲
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T19309Endothelin 1 (swine, human)Endothelin 1 (swine, human)
Endothelin 1 acts through two types of receptors ETA and ETB.?Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor.?
价 格：￥电议型 号：T19309产 地：美洲
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T5824Angiotensin IVAngiotensin IV,Angiotensin II (3-8), human?,
Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.
价 格：￥电议型 号：T5824产 地：美洲
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T8761L[Leu15]-Gastrin I human acetate(39024-57-2 Free base)；化合物 [Leu15]-Gastrin I human acetate(39024-57-2
[Leu15]-Gastrin I human acetate(39024-57-2 Free base) is a useful organic compound for research related to life sciences and the catalog number is T8761L.
价 格：￥电议型 号：T8761L产 地：中国大陆
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T8761[Leu15]-Gastrin I human；化合物T8761Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-
[Leu15]-Gastrin I human (Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2) encodes for the protein [Leu15]-Gastrin I in human. In human chromosome, the gene GAST is localized on 17q21.2. G cells in the stomach antrum produces the precursor of [Leu15]-Gastrin I, progastrin.Progastrin undergoes cleavage and processing to yield gastrin, which is trophic for the entire gastrointestinal epithelium. Gastrin is essential for the growth of the digestive system
价 格：￥电议型 号：T8761产 地：中国大陆
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T8560Angiotensin II human acetate血管紧张素IIAng II acetate|||DRVYIHPF acetate|||Angiotensin II acetate|||血管紧张
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
价 格：￥电议型 号：T8560产 地：中国大陆
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T83847SP-A (196-215) (human) TFA；化合物 SP-A (196-215) (human) TFASurfactant Protein A|||SPA4；Surfactant Prot
Surfactant protein A (SP-A) (196-215) is a synthetic peptide derived from the C-terminal carbohydrate recognition domain of human SP-A, specifically amino acids 196-215. This peptide suppresses LPS-induced TNF-α release in JAWSII mouse dendritic cells at 1 and 10 ?M concentrations and promotes phagocytosis of P. aeruginosa at a 75 ?M concentration. Furthermore, intratracheal administration of SP-A (196-215) at a dose of 50 ?g per animal reduces disease severity and lung colony-forming units in m
价 格：￥电议型 号：T83847产 地：中国大陆
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T83770Klotho-derived Peptide 1 (56-87) (human) TFA；化合物 Klotho-derived Peptide 1 (56-87) (human) TFAKP1 (56
Klotho-derived peptide 1 (KP1) (56-87), a peptide originating from the human Klotho protein, disrupts TGF-β signaling by binding to TGF-β receptor types 1 and 2 (TGFBR1 and TGFBR2; Kds = 1.41 and 14.6 ?M, respectively). Preincubation with KP1 at a concentration of 10 ?g/ml hinders the TGF-β-induced escalation of fibronectin and α-smooth muscle actin (α-SMA) levels in NRK-49F rat fibroblasts. Furthermore, in vivo studies reveal that KP1, administered at 1 mg/kg per day, preferentially accumulates
价 格：￥电议型 号：T83770产 地：中国大陆
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T837605-FAM-LL-37 (human) TFA；化合物 5-FAM-LL-37 (human) TFA5-Carboxyfluorescein LL-37；5-Carboxyfluorescein L
5-FAM-LL-37 is a fluorescently labeled antimicrobial peptide conjugated to 5-carboxyfluorescein (5-FAM) through a 6-aminohexanoic acid (Ahx) linker, featuring excitation/emission maxima at 492/518 nm, respectively. This compound integrates the functional attributes of LL-37 with the fluorescent properties of 5-FAM for enhanced visualization.
价 格：￥电议型 号：T83760产 地：中国大陆
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T83751PUMA BH3 (human) TFA；化合物 PUMA BH3 (human) TFAPUMA BH3 (human) TFA
PUMA BH3, a peptide that includes the BH3 domain from the p53-upregulated modulator of apoptosis (PUMA) and activates the pro-apoptotic protein Bak, demonstrates binding affinity to Bak with dissociation constants (Kds) of 290 nM in HEPES buffer and 26 nM in CHAPS buffer. This interaction with Bak induces its homo-oligomerization and facilitates Bak-mediated membrane permeabilization.
价 格：￥电议型 号：T83751产 地：中国大陆
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T83733TIP39 (human, bovine) TFA；化合物 TIP39 (human, bovine) TFATuberoinfundibular Peptide of 39 Residues；Tub
TIP39, a neuropeptide and an agonist for the parathyroid hormone receptor type 2 (PTH2R), effectively increases cAMP levels in COS-7 cells featuring recombinant PTH2R from humans or rats (EC50s = 0.5 and 0.8 nM, respectively), as well as in F-11 cells that naturally express PTH2R (EC50 = 1.15 nM). Furthermore, TIP39 at 1 nM halts the cell cycle at the G0/G1 phase and reduces Sox9 expression, a crucial regulator of cartilage differentiation, in CFK2 rat chondrocytes. Additionally, administering 1
价 格：￥电议型 号：T83733产 地：中国大陆
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T83712Interleukin-8 (54-72) (human) TFA；化合物 Interleukin-8 (54-72) (human) TFAIL-8 (54-72)|||C-X-C Motif Ch
Interleukin-8 (IL-8) (54-72), a peptide comprising amino acids 54-72 from the mature IL-8 sequence and 81-99 from the pre-processed form, inhibits the flow-based adhesion of primary human neutrophils to human umbilical vein endothelial cells (HUVECs).
价 格：￥电议型 号：T83712产 地：中国大陆
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T83710Gastric Inhibitory Peptide (22-51) (human) TFA；化合物 Gastric Inhibitory Peptide (22-51) (human) TFAGIP
Gastric inhibitory peptide (GIP) (22-51), a pro-atherogenic peptide comprised of 30 amino acids from the residues 22-51 of its precursor protein proGIP, is present in human plasma. It activates the degradation of IκB-α and the nuclear translocation of NF-κB in both macrophage-differentiated THP-1 cells and human aortic endothelial cells at a concentration of 1 ?M. Additionally, in ApoE-/- mice, GIP (22-51) escalates the area of atherosclerotic lesions and plaque development in vivo.
价 格：￥电议型 号：T83710产 地：中国大陆
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T83700IRBP (651-670) (human) TFA；化合物 IRBP (651-670) (human) TFAIRBP651-670|||Interphotoreceptor Retinoid-B
Interphotoreceptor retinoid-binding protein (651-670) (IRBP651-670), a peptide fragment of retinoid-binding protein 3 (also known as IRBP), plays a crucial role in the visual cycle by facilitating the transport of retinol and retinal between photoreceptor cells and the retinal pigment epithelium. This transport is essential for the regeneration of pigments necessary for vision. When administered at a dose of 300 ?g/animal, IRBP651-670 induces autoimmune uveoretinitis in C57BL/6 mice, a model pos
价 格：￥电议型 号：T83700产 地：中国大陆
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T83699LL-37 (18-37) (human) TFA；化合物 LL-37 (18-37) (human) TFAKR-20|||hCAP-18|||CAP-18|||Cathelicidin|||FAL
LL-37 (18-37), an antimicrobial peptide fragment of LL-37, exhibits activity against S. aureus and C. albicans, with minimum lethal concentrations of 4 ?M and 10 ?M, respectively. Additionally, it inhibits E. histolytica trophozoites growth at concentrations between 10 to 50 ?M.
价 格：￥电议型 号：T83699产 地：中国大陆
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T83697PAMP-12 (human, mouse, rat, porcine, bovine) TFA；化合物 PAMP-12 (human, mouse, rat, porcine, bovine) TF
Proadrenomedullin N-terminal 12 peptide (PAMP-12), an endogenous fragment originating from the adrenal medulla and spanning amino acids 9-20 of human PAMP-20, plays a role in causing hypotension. It functions as an agonist for the MAS-related G protein-coupled receptor family member X2 (MRGPRX2), inhibiting forskolin-stimulated cAMP accumulation in CHO cells expressing human MRGPRX2 (EC50 = 57.2 nM) and selectively prompting calcium mobilization in these cells (EC50 = 41 nM), but not in cells ex
价 格：￥电议型 号：T83697产 地：中国大陆
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T83696Gastric Inhibitory Peptide 1 (3-42) (human) TFA；化合物 Gastric Inhibitory Peptide 1 (3-42) (human) TFAG
Gastric inhibitory peptide 1 (GIP-1) (3-42), a fragment of the incretin hormone GIP and antagonist to the GIP receptor, is generated through the action of serum dipeptidyl peptidase 4 (DDP-4). When administered at 25 nmol/kg to an ob/ob mouse diabetes model, GIP-1 (3-42) elevates plasma glucose levels and lowers plasma insulin levels, demonstrating its effect on reducing insulin secretion from BRIN-BD11 pancreatic cells at a concentration of 100 nM.
价 格：￥电议型 号：T83696产 地：中国大陆
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T83695MOG Peptide (human, bovine) acetate；化合物 MOG Peptide (human, bovine) acetateMyelin Oligodendrocyte Gl
Myelin oligodendrocyte glycoprotein (MOG) peptide, a truncated form of MOG located on the extracellular myelin sheath surface, interacts with antigen serotype HLA-DR2 to mitigate effects of ischemic stroke induced by middle cerebral artery occlusion (MCAO) in mice. In female mice, it notably reduces cortical and striatal infarct volumes, lessens sensorimotor deficits as observed in tube- and corner turn tests, enhances engagement with novel odors, and prolongs the duration of cage mate-directed
价 格：￥电议型 号：T83695产 地：中国大陆
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T83692EGFR Peptide (human, mouse) (myristoylated) TFA；化合物 EGFR Peptide (human, mouse) (myristoylated) TFAM
EGFR peptide (myristoylated), a synthetic peptide inhibitor of PKC (IC50 = 5 ?M), corresponds to the intracellular region´s amino acid sequence of EGFR. It effectively reverses doxorubicin resistance in UV-2237M (UV-2237M-ADRR) fibrosarcoma cells at a concentration of 1 ?M.
价 格：￥电议型 号：T83692产 地：中国大陆
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T83691EGFR Peptide (human, mouse) TFA；化合物 EGFR Peptide (human, mouse) TFAArg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-O
EGFR peptide, a PKC peptide substrate, mirrors an amino acid sequence from EGFR´s intracellular region and serves to gauge PKC activity in primary bovine retinal endothelial cells. At a concentration of 50 ?M, unlike its myristoylated counterpart, EGFR peptide does not inhibit PKC activity.
价 格：￥电议型 号：T83691产 地：中国大陆
