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T62202mGluR2 modulator 1;化合物 mGluR2 modulator 1mGluR2 modulator 1
mGluR2 modulator 1 (compound 95) is a potent, blood-brain-barrier permeable modulator of mGluR2 (metabotropic glutamate receptor-2) positive transmutation (EC50: 0.03 μM). mGluR2 modulator 1 can be used in the study of psychiatric disorders.
价 格:¥电议型 号:T62202产 地:中国大陆
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T62133TRPC5 modulator-1;化合物 TRPC5 modulator-1TRPC5 modulator-1
TRPC5 modulator-1 (Compound 9) is a TRPC5 modulator (IC50<1 nM) that can be used to study neuropsychiatric disorders.
价 格:¥电议型 号:T62133产 地:中国大陆
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T62016CB1R Allosteric modulator 1;化合物 CB1R Allosteric modulator 1CB1R Allosteric modulator 1
CB1R Allosteric modulator 1 (compound 11) is a potent allosteric modulator of CB1R. CB1R Allosteric modulator 1 negatively affects the functional activity of orthosteric ligands (NAM) at CB1Rs.
价 格:¥电议型 号:T62016产 地:中国大陆
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T62007CXCR4 modulator-1;化合物 CXCR4 modulator-1CXCR4 modulator-1
CXCR4 modulator-1 (compound ZINC72372983) is a potent CXCR4 modulator (EC 50= 100 nM). CXCR4 modulator-1 has research value in anti-inflammatory, anticancer and anti-HIV.
价 格:¥电议型 号:T62007产 地:中国大陆
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T61924NMDA receptor modulator 6;化合物 NMDA receptor modulator 6NMDA receptor modulator 6
NMDA receptor regulator 6 (Compound 183) is an effective NMDA receptor regulator and has research value in neurological disorders.
价 格:¥电议型 号:T61924产 地:中国大陆
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T61901σ1 Receptor/μ Opioid receptor modulator 1;化合物 σ1 Receptor/μ Opioid receptor modulator 1σ1 Receptor/μ
σ 1 Receptor/ μ Opioid receiver modulator 1 (Compound 44) is an effective σ 1 receptor antagonist (Ki=1.86 nM) and μ Opioid receptor agonists (Ki=2.1 nM). Opioid receptor modulator 1 shows potent analgesic activity, and can be used for the research of neuropathic pain.
价 格:¥电议型 号:T61901产 地:中国大陆
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T61881γ-Secretase modulator 12;化合物 γ-Secretase modulator 12γ-Secretase modulator 12
γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM. It is specifically designed for Alzheimer´s disease research. Notably, γ-Secretase modulator 12 exhibits a favorable brain/plasma ratio (Kp, brain = 0.72) in mice [1].
价 格:¥电议型 号:T61881产 地:中国大陆
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T61645Utrophin modulator 1;化合物 Utrophin modulator 1Utrophin modulator 1
Utrophin Modulator 1 (UM1) is a highly effective agent that upregulates utrophin protein levels, displaying an EC 50 of 0.11 μM. Its application in the investigation of Duchenne Muscular Dystrophy (DMD) has been well-established [1].
价 格:¥电议型 号:T61645产 地:中国大陆
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T61562CB1R Allosteric modulator 3;CB1R变构调节剂3CB1R Allosteric modulator 3
CB1R Allosteric modulator 3 is a potent CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP and β-Arrestin, and can be used for the study of obesity and nicotine addiction.
价 格:¥电议型 号:T61562产 地:中国大陆
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T61483GLP-1R modulator C5;化合物GLP-1R modulator C5GLP-1R modulator C5
GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.
价 格:¥电议型 号:T61483产 地:中国大陆
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T61371CB1R Allosteric modulator 4;化合物 CB1R Allosteric modulator 4CB1R Allosteric modulator 4
CB1R Allosteric modulator 4 is an effective and positive modulator of cannabinoid type-1 (CB1R), exhibiting significant biological activity. This compound inhibits the production of cAMP and demonstrates strong β-arrestin-2 recruitment [1].
价 格:¥电议型 号:T61371产 地:中国大陆
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T61332MRGPRX4 modulator-1;化合物 MRGPRX4 modulator-1MRGPRX4 modulator-1
MRGPRX4 modulator-1 (compound 31-2) is a potent antagonist of the mas-related g-protein receptor X4 (MRGPR X4) with an IC50 < 100 nM against MRGPR4. It is utilized for the investigation of MRGPR X4 dependent diseases including itch, pain, and autoimmune disorders [1].
价 格:¥电议型 号:T61332产 地:中国大陆
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T61277mGluR2 modulator 4;化合物 mGluR2 modulator 4mGluR2 modulator 4
mGluR2 modulator 4 (compound 47) is a highly potent positive allosteric modulator of mGluR2, exhibiting an EC 50 value of 0.8 μM. It holds the potential for investigating antipsychotic properties [1].
价 格:¥电议型 号:T61277产 地:中国大陆
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T61276CB1R Allosteric modulator 2;化合物 CB1R Allosteric modulator 2CB1R Allosteric modulator 2
CB1R Allosteric modulator 2 (compound 18) is a potent allosteric modulator of the CB1R receptor. It exhibits negative modulation of the functional activity of orthosteric ligands (NAM) at CB1Rs, as demonstrated in previous studies [1].
价 格:¥电议型 号:T61276产 地:中国大陆
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T61183MRGPRX4 modulator-2;化合物 MRGPRX4 modulator-2MRGPRX4 modulator-2
MRGPRX4 modulator-2 (compound 1-55) is a highly potent modulator of MRGPR X4, displaying antagonist activity against this receptor with an IC50 value of less than 100 nM. Its application in the research of autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson´s Syndrome, and various chronic itch conditions is notable [1].
价 格:¥电议型 号:T61183产 地:中国大陆
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T61117NMDA receptor modulator 5;化合物 NMDA receptor modulator 5NMDA receptor modulator 5
NMDA receptor modulator 5 (Compound 195), a potent NMDA receptor modulator, exhibits potential for neurological disorder research [1].
价 格:¥电议型 号:T61117产 地:中国大陆
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T60986KCa2 channel modulator 2;化合物 KCa2 channel modulator 2KCa2 channel modulator 2
KCa2 channel modulator 2 (compound 2q) is an effective subtype-selective K/Ca 2 channel positive modulator which shows similar potency on the human K Ca 2.3 channel and rat K Ca 2.2a subtypes, with EC50 values of 0.60 μM and 0.64 μM, respectively [1].
价 格:¥电议型 号:T60986产 地:中国大陆
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T60985KCa2 channel modulator 1;化合物 KCa2 channel modulator 1KCa2 channel modulator 1
KCa2 channel modulator 1 (compound 2o) is an effective subtype-selective K/Ca2 channel positive modulator that potentiates rat K Ca 2.2 channel subtype with an EC 50 value of 0.99 μM and human K Ca 2.3 channels subtype with an EC 50 value of 0.19 μM [1].
价 格:¥电议型 号:T60985产 地:中国大陆
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T60960NMDA receptor modulator 4;化合物 NMDA receptor modulator 4NMDA receptor modulator 4
NMDA receptor modulator 4 (Compound 169) can be used for the research of neurological disorder that is a potent modulator of NMDA receptor [1].
价 格:¥电议型 号:T60960产 地:中国大陆
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T60882mGluR2 modulator 2;化合物 mGluR2 modulator 2mGluR2 modulator 2
mGluR2 modulator 2 (compound 2) can be used in antipsychotic research. mGluR2 modulator 2 is a potent, selective and orally bioavailable positive allosteric modulator of mGluR2 with an EC 50 value of 0.13 μM [1].
价 格:¥电议型 号:T60882产 地:中国大陆