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T10455Bafilomycin B1巴佛洛霉素 B1巴佛洛霉素 B1
Bafilomycin B1, a macrolide antibiotic isolated from Streptomyces sp, acts as an inhibitor of K+-dependent ATPase of E. coli. It also inhibits Gram-positive bacteria and fungi.
价 格：￥电议型 号：T10455产 地：中国大陆
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T10443Aβ42-IN-1 free base；化合物 T10443Aβ42-IN-1 free base
Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091 μM, and significantly diminishes brain Aβ42 levels in mice. Given these properties, Aβ42-IN-1 free base represents a potential disease-modifying agent for Alzheimer’s disease [1].
价 格：￥电议型 号：T10443产 地：中国大陆
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T10436LAZD4573 HCl (2057509-72-3 free base)；化合物 T10436LAZD4573 hydrochloride|||AZD4573|||AZD4573 HCl|||AZD-
AZD-4573 is a selective and short-acting inhibitor of the serine/threonine cyclin-dependent kinase 9, the catalytic subunit of the RNA polymerase II elongation factor positive transcription elongation factor b. It also has a potential antineoplastic activity.
价 格：￥电议型 号：T10436L产 地：中国大陆
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T1043Multifungin；溴柳氯苯胺Bromochlorosalicylanilide|||Salifungin；Bromochlorosalicylanilide|||溴柳氯苯胺|||Salifung
Multifungin (Bromochlorosalicylanilide) is an antifungal that studies oral candidiasis. It reduces the number of fungal populations in corn during storage and prevents the formation and accumulation of zearalenone.
价 格：￥电议型 号：T1043产 地：中国大陆
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T10427AZ505 ditrifluoroacetate；化合物 T10427AZ505 ditrifluoroacetate
AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).
价 格：￥电议型 号：T10427产 地：中国大陆
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T10422Avibactam free acid；化合物 T10422NXL-104 free acid；NXL-104 free acid
Avibactam (NXL-104) free acid is a covalent and reversible inhibitor of non-β-lactam β-lactamase (IC50s: 8 nM and 5 nM for β-lactamase TEM-1 and CTX-M-15).
价 格：￥电议型 号：T10422产 地：中国大陆
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T10420Avarofloxacin；化合物 T10420JNJ-Q2；JNJ-Q2
Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and community-acquired pneumonia and skin structure infections.
价 格：￥电议型 号：T10420产 地：中国大陆
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T10408ATWLPPR Peptide TFA；化合物 T10408ATWLPPR Peptide TFA
ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor and inhibits VEGF165 binding to NRP-1. It has the potential in reducing the early retinal damage caused by diabetes.
价 格：￥电议型 号：T10408产 地：中国大陆
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T10402Atorvastatin Epoxy Tetrahydrofuran Impurity；化合物 T10402Atorvastatin Epoxy Tetrahydrofuran Impurity
Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor.
价 格：￥电议型 号：T10402产 地：中国大陆
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T10397ATN-161 trifluoroacetate salt；化合物ATN-161 trifluoroacetate saltATN-161 TFA salt；ATN-161 TFA salt
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.
价 格：￥电议型 号：T10397产 地：中国大陆
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T10395ATM-3507 trihydrochloride (1861449-70-8 free base)；化合物 T10395ATM-3507 trihydrochloride；ATM-3507 trih
ATM-3507 trihydrochloride is a potent tropomyosin inhibitor (IC50s: 3.83-6.84 μM in human melanoma cell lines).
价 格：￥电议型 号：T10395产 地：中国大陆
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T10394LATB107 hydrochloride；化合物ATB107盐酸盐ATB107 hydrochloride(455325-51-6 Free base)；ATB107 hydrochloride(45
ATB107 hydrochloride is a novel and potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM.
价 格：￥电议型 号：T10394L产 地：中国大陆
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T10384Farudodstat；化合物ASLAN003ASLAN003；ASLAN003
Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.
价 格：￥电议型 号：T10384产 地：中国大陆
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T10382AS2863619 free base；化合物 T10382AS2863619 free base
AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells. It is a potent, orally active CDK8 and CDK19 inhibitor (IC50s: 0.61 nM and 4.28 nM). STAT5 activation enhanced by AS2863619 free base inhibition of CDK8/19, which consequently activates the Foxp3 gene.
价 格：￥电议型 号：T10382产 地：中国大陆
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T1038Fludarabine；氟达拉滨NSC 118218|||Fludarabinum|||F-ara-A；NSC 118218|||Fludarabinum|||氟达拉宾|||氟达拉滨|||F-ara-
Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and lymphoma.
价 格：￥电议型 号：T1038产 地：中国大陆
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T10379Arzoxifene hydrochloride；化合物 T10379SERM 3|||LY 353381 HCl；SERM 3|||LY 353381 HCl
Arzoxifene hydrochloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue.
价 格：￥电议型 号：T10379产 地：中国大陆
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T10377Artefenomel；化合物 T10377OZ439；OZ439
Artefenomel (OZ439) is a synthetic antimalarial agent with the artemisinin pharmacophore.
价 格：￥电议型 号：T10377产 地：中国大陆
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T10373(R)-Filanesib；化合物 T10373(R)-ARRY-520；(R)-ARRY-520
(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).
价 格：￥电议型 号：T10373产 地：中国大陆
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T10366LArg-Gly-Asp-Ser acetate；化合物Arg-Gly-Asp-Ser acetateArg-Gly-Asp-Ser acetate(91037-65-9 free base)；Arg-
Arg-Gly-Asp-Ser acetate is an integrin binding sequence that directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1. Arg-Gly-Asp-Ser acetate inhibits integrin receptor function.
价 格：￥电议型 号：T10366L产 地：中国大陆
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T10366Arg-Gly-Asp-Ser化合物 T10366Fibronectin tetrapeptide|||RGDS peptide
Arg-Gly-Asp-Ser is an integrin-binding sequence that inhibits integrin receptor function. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, MMP-9, and iNOS.
价 格：￥电议型 号：T10366产 地：中国大陆
