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  • T4214KDM4D-IN-1；化合物KDM4D-IN-1KDM4D-IN-1

    KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).

    价 格：￥电议型 号：T4214产 地：中国大陆

  • T4198T.cruzi-IN-1；T.cruzi InhibitorMDK1088|||T.cruzi Inhibitor；MDK1088|||T.cruzi Inhibitor

    T.cruzi-IN-1 (MDK1088) is a Trypanosoma cruzi inhibitor.

    价 格：￥电议型 号：T4198产 地：中国大陆

  • T4170PKM2-IN-1；化合物PKM2 inhibitorPKM2 inhibitor|||compound 3k；PKM2 inhibitor|||compound 3k

    PKM2-IN-1 (compound 3k) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2.

    价 格：￥电议型 号：T4170产 地：中国大陆

  • T4140IRAK4-IN-1；化合物IRAK4-IN-1IRAK4-IN-1

    IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.

    价 格：￥电议型 号：T4140产 地：中国大陆

  • T41002HCVP-IN-1；HCVP-IN-1HCVP-IN-1

    HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.

    价 格：￥电议型 号：T41002产 地：中国大陆

  • T40835PTP1B-IN-14PTP1B-IN-14PTP1B-IN-14

    PTP1B-IN-14 is a selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) that targets the allosteric site, exhibiting an inhibitory concentration (IC50) value of 0.72 μM.

    价 格：￥电议型 号：T40835产 地：中国大陆

  • T4075Sulfatinib；索凡替尼KDR-IN-1；KDR-IN-1|||索凡替尼

    Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to 24 nM.

    价 格：￥电议型 号：T4075产 地：中国大陆

  • T40745PTP1B-IN-13PTP1B-IN-13PTP1B-IN-13

    PTP1B-IN-13, a potent and selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B), effectively targets the allosteric site, exhibiting an IC50 value of 1.59 μM.

    价 格：￥电议型 号：T40745产 地：中国大陆

  • T40552ACAT-IN-10；ACAT-IN-10ACAT-IN-10

    ACAT-IN-10 is an acyl-Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. It inhibits NF-κB mediated transcription with a weak activity.

    价 格：￥电议型 号：T40552产 地：中国大陆

  • T40396FgGpmk1-IN-1FgGpmk1-IN-1FgGpmk1-IN-1

    FgGpmk1-IN-1 is a new inhibitor of the fusarium graminearum mitogen-activated protein kinase (FgGpmk1), displaying a potency with an EC50 value of 3.46 μg/mL.

    价 格：￥电议型 号：T40396产 地：中国大陆

  • T40353CDK7/9-IN-1CDK7/9-IN-1CDK7/9-IN-1

    CDK7/9-IN-1 is a specific inhibitor of cyclin-dependent kinases 7/9 (CDK7/9). It specifically targets CDK7, while also displaying inhibitory activity against CDK9. CDK7/9-IN-1 demonstrates excellent inhibitory potency against CDK7, with IC50 values of 0.0656 μM and 0.00574 μM without pre-incubation and after 3 hours pre-incubation, respectively. Furthermore, CDK7/9-IN-1 inhibits CDK9 with an IC50 of 2.14 μM after 3 hours pre-incubation. Its application in cancer research makes it valuable for su

    价 格：￥电议型 号：T40353产 地：中国大陆

  • T40348TTBK1-IN-1；TTBK1-IN-1TTBK1-IN-1；TTBK1-IN-1

    TTBK1-IN-1 is a highly potent and selective inhibitor of tau tubulin kinase 1 (TTBK1), capable of penetrating the blood-brain barrier with ease. With an IC 50 value of 2.7 nM, TTBK1-IN-1 exhibits strong inhibitory activity against TTBK1. This compound holds great promise for advancing research in Alzheimer´s disease and other tauopathies.

    价 格：￥电议型 号：T40348产 地：中国大陆

  • T40344CBP/p300-IN-14CBP/p300-IN-14CBP/p300-IN-14

    CBP/p300-IN-14, efficiently inhibits CBP/EP300 (lysine acetyltransferase) with an IC50 value of 3.3 nM.

    价 格：￥电议型 号：T40344产 地：中国大陆

  • T40341SARS-CoV-2-IN-11；SARS-CoV-2-IN-11SARS-CoV-2-IN-11

    SARS-CoV-2-IN-11 is a highly potent and non-toxic inhibitor of the 3C-like protease (3CLpro) of SARS-CoV-2, demonstrating IC50 and EC50 values of 0.17 nM and 1.45 nM, respectively. This compound targets the essential viral replication enzyme, 3CLpro, making it an attractive candidate for intervention strategies. SARS-CoV-2-IN-11 holds significant promise in the development of specific antivirals against SARS-CoV-2.

    价 格：￥电议型 号：T40341产 地：中国大陆

  • T40340SARS-CoV-2-IN-10；SARS-CoV-2-IN-10SARS-CoV-2-IN-10

    SARS-CoV-2-IN-10 is a powerful and non-toxic inhibitor of SARS-CoV-2 3CL protease, with IC50 and EC50 values of 0.13 nM and 1.03 nM, respectively. The SARS-CoV-2 3C-like protease (3CLpro) is a critical enzyme for viral replication and serves as an ideal target for intervention. By targeting the SARS-CoV-2 3CL protease, SARS-CoV-2-IN-10 has the potential to facilitate the development of effective antiviral drugs specific to SARS-CoV-2.

    价 格：￥电议型 号：T40340产 地：中国大陆

  • T40319PIM-IN-1；PIM-IN-1PIM-IN-1

    PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC 50 = 61 nM; pS6, EC 50 = 71 nM).

    价 格：￥电议型 号：T40319产 地：中国大陆

  • T40317α/β-Hydrolase-IN-1；α/β-Hydrolase-IN-1α/β-Hydrolase-IN-1

    α/β-Hydrolase-IN-1 demonstrates exceptional potency, with MICs of 50 μM (25 μg/mL) against M. smegmatis and 16 μM (8.4 μg/mL) against M. tuberculosis H37Ra, establishing it as a superior compound in this class.

    价 格：￥电议型 号：T40317产 地：中国大陆

  • T40312Plasma kallikrein-IN-1；Plasma kallikrein-IN-1Plasma kallikrein-IN-1

    Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.

    价 格：￥电议型 号：T40312产 地：中国大陆

  • T40310PARP/EZH2-IN-1PARP/EZH2-IN-1PARP/EZH2-IN-1

    PARP/EZH2-IN-1 is a novel compound that functions as a dual inhibitor for both PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM), showing promising potential for the treatment of triple-negative breast cancer with wild-type BRCA.

    价 格：￥电议型 号：T40310产 地：中国大陆

  • T40309DHODH-IN-18；DHODH-IN-18DHODH-IN-18

    DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).

    价 格：￥电议型 号：T40309产 地：中国大陆

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