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  • T40092MNK/PIM-IN-1；MNK/PIM-IN-1MNK/PIM-IN-1

    MNK/PIM-IN-1 is a novel dual inhibitor targeting both MNK and PIM pathways, characterized by its favorable pharmacokinetic profile.

    价 格：￥电议型 号：T40092产 地：中国大陆

  • T40071Cavα2δ-IN-1；Cavα2δ-IN-1Cavα2δ-IN-1

    Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki value greater than 10,000 nM).

    价 格：￥电议型 号：T40071产 地：中国大陆

  • T40051Acid Ceramidase-IN-1；Acid Ceramidase-IN-1Acid Ceramidase-IN-1

    Acid Ceramidase-IN-1 is a highly effective and orally bioavailable inhibitor of acid ceramidase (AC, ASAH-1), with an inhibitory concentration (IC50) of 0.166 μM. Additionally, Acid Ceramidase-IN-1 exhibits exceptional brain penetration capabilities in mice.

    价 格：￥电议型 号：T40051产 地：中国大陆

  • T40047CDK6/9-IN-1CDK6/9-IN-1CDK6/9-IN-1

    CDK6/9-IN-1 (compound 66) is a potent dual inhibitor of CDK 6 and CDK 9 that can be administered orally. It exhibits inhibitory activity with IC 50 values of 40.5 nM and 39.5 nM against CDK6 and CDK9, respectively.

    价 格：￥电议型 号：T40047产 地：中国大陆

  • T39993PRMT5-IN-15PRMT5-IN-15PRMT5-IN-15

    PRMT5-IN-15 is a PRMT5 inhibitor with an IC 50 value of 0.84 nM.

    价 格：￥电议型 号：T39993产 地：中国大陆

  • T39982DGK-IN-1；DGK-IN-1DGK-IN-1

    DGK-IN-1, an extracted T cell activator, holds potential in leveraging tumor immunity.

    价 格：￥电议型 号：T39982产 地：中国大陆

  • T39947WSF1-IN-1WSF1-IN-1WSF1-IN-1

    WSF1-IN-1 (compound 136) is an orally active inhibitor of WSF1, intended for the study of WSF1-related tumors in patients with Wolfram syndrome (WS). In HepG2 parental and HepG2 WFS1 KO cell lines, WSF1-IN-1 has demonstrated IC50 values of 0.33 μM and >27 μM, respectively.

    价 格：￥电议型 号：T39947产 地：中国大陆

  • T39946IDO1-IN-12IDO1-IN-12IDO1-IN-12

    IDO1-IN-12 is a potent and orally available IDO1 inhibitor.

    价 格：￥电议型 号：T39946产 地：中国大陆

  • T39935TRPA1-IN-1TRPA1-IN-1TRPA1-IN-1

    TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.

    价 格：￥电议型 号：T39935产 地：中国大陆

  • T39934PRMT5-IN-13PRMT5-IN-13PRMT5-IN-13

    PRMT5-IN-13 is a selective inhibitor of protein arginine methyltransferase 5 (prmt5) .

    价 格：￥电议型 号：T39934产 地：中国大陆

  • T39932ARG1-IN-1ARG1-IN-1ARG1-IN-1

    ARG1-IN-1 is a human arginase 1 inhibitor with an IC 50 of 29 nM.

    价 格：￥电议型 号：T39932产 地：中国大陆

  • T39883Polyketide synthase 13-IN-1；Polyketide synthase 13-IN-1Polyketide synthase 13-IN-1

    Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor.

    价 格：￥电议型 号：T39883产 地：中国大陆

  • T39839IDO1-IN-11IDO1-IN-11IDO1-IN-11

    IDO1-IN-11 is an IDO1 inhibitor with an IC 50 value of 0.6 nM.

    价 格：￥电议型 号：T39839产 地：中国大陆

  • T39827c-ABL-IN-1；c-ABL-IN-1c-ABL-IN-1

    C-ABL-IN-1 is a new and specific inhibitor of the c-Abl protein, which effectively prevents the progression of neurodegeneration observed in Parkinson´s disease.

    价 格：￥电议型 号：T39827产 地：中国大陆

  • T39809PRMT5-IN-14PRMT5-IN-14PRMT5-IN-14

    PRMT5-IN-14 is a PRMT5 inhibitor to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.

    价 格：￥电议型 号：T39809产 地：中国大陆

  • T39796PDE12-IN-1PDE12-IN-1PDE12-IN-1

    PDE12-IN-1 is a powerful and specific inhibitor of PDE12, exhibiting a pIC 50 value of 9.1 for enzyme inhibition. It effectively enhances levels of 2′,5′-linked adenylate polymers (2-5A), with a pEC 50 value of 7.7. Additionally, PDE12-IN-1 demonstrates antiviral activity.

    价 格：￥电议型 号：T39796产 地：中国大陆

  • T39781Aβ/tau aggregation-IN-1；Aβ/tau aggregation-IN-1Aβ/tau aggregation-IN-1

    Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ 1-42 β-sheet formation and tau aggregation. It exhibits K D values of 160 μM and 337 μM with Aβ 1-42 and tau, respectively. Additionally, Aβ/tau aggregation-IN-1 can penetrate the blood-brain barrier efficiently.

    价 格：￥电议型 号：T39781产 地：中国大陆

  • T39778Influenza A virus-IN-1；Influenza A virus-IN-1Influenza A virus-IN-1

    Influenza A virus-IN-1, a dihydropyrrolidones derivative, is a highly effective inhibitor of various subtypes of influenza A virus (IAV) with IC 50 values ranging from 3.11 μM to 7.13 μM. It effectively suppresses IAV replication and enhances the expression of key antiviral cytokines, such as IFN-β, and the antiviral protein MxA.

    价 格：￥电议型 号：T39778产 地：中国大陆

  • T39705ATG7-IN-1；化合物ATG7-IN-1ATG7-IN-1；ATG7-IN-1

    ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.

    价 格：￥电议型 号：T39705产 地：中国大陆

  • T39675ALDH1A2-IN-1ALDH1A2-IN-1ALDH1A2-IN-1

    ALDH1A2-IN-1 is a reversible inhibitor of the active site of ALDH1A2, showing a significant affinity for the enzyme with an IC50 value of 0.91 μM and a Kd value of 0.26 μM. This compound interacts hydrophobically with the enzyme, contributing to its inhibitory properties.

    价 格：￥电议型 号：T39675产 地：中国大陆

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