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T10318Anatabine dicitrate;化合物 T10318Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. It is a potent α4β2 nAChR agonist and inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of the amyloid precursor protein.
价 格:¥电议型 号:T10318产 地:中国大陆
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T10308AMPD2 inhibitor 1;化合物 T10308AMPD2 inhibitor 1
AMPD2 inhibitor 1 is an inhibitor of adenosine monophosphate deaminase 2 (AMPD2), used in the research of salt craving, sugar craving, umami craving, and addictions including tobacco, drug, nicotine and alcohol addictions.
价 格:¥电议型 号:T10308产 地:中国大陆
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T10298LAMG-548;化合物 T10298LAMG-548
AMG-548 is an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ and is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM)[1]. AMG-548 inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε[2].
价 格:¥电议型 号:T10298L产 地:中国大陆
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T10298AMG-548 hydrochloride (864249-60-5 free base);化合物 T10298AMG-548 hydrochloride;AMG-548 hydrochloride
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50: 3 nM).
价 格:¥电议型 号:T10298产 地:中国大陆
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T10297LAMG 487;化合物AMG 487AMG 487
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
价 格:¥电议型 号:T10297L产 地:中国大陆
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T10290LAlpertine HCl;阿尔哌汀盐酸盐Win 31665 HCl|||Alpertine HCl(27076-46-6 Free base);Win 31665 HCl|||Alpertine H
Alpertine HCl is a small molecule compound with anti-neuropathic properties.
价 格:¥电议型 号:T10290L产 地:中国大陆
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T10288Alogliptin (13CD3);化合物 T10288SYR-322 (13CD3);SYR-322 (13CD3)
Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.
价 格:¥电议型 号:T10288产 地:中国大陆
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T1028Moxonidine;莫索尼定BDF5895;莫索尼定|||BDF5895|||莫索尼啶
Moxonidine (BDF5895) is a selective agonist at the imidazoline receptor subtype 1, acting as an antihypertensive drug.
价 格:¥电议型 号:T1028产 地:中国大陆
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T10278Alamethicin;丙甲菌素Alamethicin
Alamethicin is isolated from Trichoderma viride. It is a channel-forming peptide antibiotic and induces voltage-gated conductance in model and cell membranes.
价 格:¥电议型 号:T10278产 地:中国大陆
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T10276LAKT Kinase Inhibitor HCl;AKT Kinase抑制剂盐酸盐AKT Kinase Inhibitor HCl(842148-40-7 Free base);AKT Kinase
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.
价 格:¥电议型 号:T10276L产 地:中国大陆
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T1027Luteolin;木犀草素Luteolol|||Flacitran|||Digitoflavone|||Luteoline;木犀草素|||Luteolol|||Flacitran|||Digitofl
Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities including antitumor, antioxidant, anti-inflammatory, antimicrobial, antiviral, antiallergic, and procoagulant.
价 格:¥电议型 号:T1027产 地:中国大陆
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T10268AGX51;化合物AGX51AGX51
AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.
价 格:¥电议型 号:T10268产 地:中国大陆
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T10267Agomelatine (L(+)-Tartaric acid);阿戈美拉汀 L(+)-酒石酸S-20098 L(+)-Tartaric acid;阿戈美拉汀 L(+)-酒石酸|||S-20098 L
Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2). It also is a selective 5-HT2C receptor antagonist (pKis: 6.4 and 6.2 at native (porcine) and cloned (human) 5-HT2C receptors).
价 格:¥电议型 号:T10267产 地:中国大陆
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T10265AGN 194078;化合物 T10265AGN 194078
AGN 194078 is a selective RARα agonist (Kd: 3 nM; EC50: 112 nM).
价 格:¥电议型 号:T10265产 地:中国大陆
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T10263AGN 205728;化合物 T10263AGN 205728
AGN 205728 is a potent and selective RARγ antagonist (Ki: 3 nM; IC95: 0.6 nM) and has no inhibition on RARα and RARβ.
价 格:¥电议型 号:T10263产 地:中国大陆
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T10258AFP464 free base;化合物 T10258NSC710464 free base;NSC710464 free base
AFP464 (NSC710464) free base is an active HIF-1α inhibitor (IC50: 0.25 μM) and a potent aryl hydrocarbon receptor (AhR) activator.
价 格:¥电议型 号:T10258产 地:中国大陆
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T10252L2ADU-S100 ammonium salt;化合物ADU-S100 ammonium saltML RR-S2 CDA ammonium salt|||MIW815 ammonium salt;ML
ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) is an activator of stimulator of interferon genes (STING). ADU-S100 ammonium salt leads to potent and systemic tumor regression and immunity.
价 格:¥电议型 号:T10252L2产 地:中国大陆
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T10252LADU-S100 enantiomer ammonium salt;化合物 T10252LMIW815 enantiomer ammonium salt|||ML RR-S2 CDA enantiom
ADU-S100 (MIW815) enantiomer ammonium salt is the less active enantiomer of ADU-S100. ADU-S100 is an activator of the stimulator of interferon genes (STING).
价 格:¥电议型 号:T10252L产 地:中国大陆
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T1025Tranylcypromine (2-PCPA) hydrochloride反苯环丙胺盐酸盐反苯环丙胺盐酸盐|||Tranylcypromine (2-PCPA) HCl|||SKF-385 HCl
Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl), a Monoamine Oxidase inhibitor, is effective in the treatment of major depression, dysthymic disorder, and atypical depression.
价 格:¥电议型 号:T1025产 地:中国大陆
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T10248Adenosine antagonist-1;腺苷拮抗剂1Adenosine antagonist-1
Adenosine antagonist-1 acts as an adenosine A3 receptor (AA3R) antagonist.
价 格:¥电议型 号:T10248产 地:中国大陆