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T10239Acolbifene；阿考比芬EM-652|||SCH 57068；阿考比芬|||EM-652|||SCH 57068
Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifene shows an anticarcinogenic property.
价 格：￥电议型 号：T10239产 地：中国大陆
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T10238Aclacinomycin A hydrochloride；盐酸阿柔比星Aclarubicin hydrochloride；盐酸阿柔比星|||Aclarubicin hydrochloride
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinomycin A hydrochloride is also a dual inhibitor of topoisomerase I and II.
价 格：￥电议型 号：T10238产 地：中国大陆
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T10236LACHN-975；化合物 T10236LACHN-975
ACHN-975 is a highly potent and selective LpxC inhibitor, demonstrating subnanomolar inhibitory activity. It effectively targets a broad spectrum of gram-negative bacteria, with low minimum inhibitory concentration (MIC) values (≤1 μg/mL)[1].
价 格：￥电议型 号：T10236L产 地：中国大陆
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T10228AC710 Mesylate；化合物 T10228AC710 Mesylate
AC710 Mesylate is a potent PDGFR inhibitor (Kds: 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ).
价 格：￥电议型 号：T10228产 地：中国大陆
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T10221LAbeprazan；化合物 T10221LDWP14012|||Abeprazan|||DWP-14012|||DWP14012|||DWP 14012|||DWP14012|||Abeprazan；
Abeprazan (DWP14012) is a potassium-competitive acid blocker and it is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases[1]. Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required.
价 格：￥电议型 号：T10221L产 地：中国大陆
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T10218Abatacept；化合物 T10218CTLA4lg；CTLA4lg
Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extracellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation modulator and a protein drug for autoimmune diseases.
价 格：￥电议型 号：T10218产 地：中国大陆
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T10217LAbarelix；阿巴瑞克R3827|||PPI 149；R3827|||阿巴瑞克|||PPI 149
Abarelix (PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment.
价 格：￥电议型 号：T10217L产 地：中国大陆
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T10212A2AR-agonist-1；化合物A2AR-agonist-1N-(2-(1H-Indol-3-yl)ethyl)adenosine；N-(2-(1H-Indol-3-yl)ethyl)adenos
A2AR-agonist-1 (N-(2-(1H-Indol-3-yl)ethyl)adenosine) is a potent A2AR and ENT1 agonist (Ki: 4.39 and 3.47 for A2AR and ENT1. It targets the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection.
价 格：￥电议型 号：T10212产 地：中国大陆
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T10210A-9758；化合物 T10210A-9758
A-9758 is a RORγ ligand and a selective RORγt inverse agonist (IC50: 5 nM) and exhibits robust potency against IL-17A release. It is effective in suppressing both Th17 differentiation and Th17 effector function. A-9758 significantly attenuates IL-23 driven psoriasiform dermatitis.
价 格：￥电议型 号：T10210产 地：中国大陆
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T10208A-69412；化合物A-69412N-1-(Fur-3-ylethyl)-N-hydroxyurea；N-1-(Fur-3-ylethyl)-N-hydroxyurea
A-69412 (N-1-(Fur-3-ylethyl)-N-hydroxyurea) is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other inflammatory and allergic conditions.
价 格：￥电议型 号：T10208产 地：中国大陆
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T101988-M-PDOT；8-甲氧基-2-丙胺四氢萘8-Methoxy-2-propionamidotetralin|||AH-002；8-Methoxy-2-propionamidotetralin|||A
8-M-PDOT (AH-002) is a selective and potent melatonin MT2 receptor agonist that also inhibits MT1 receptors.8-M-PDOT has anxiolytic activity and may be used to study MT2-induced neuropathic pain.
价 格：￥电议型 号：T10198产 地：中国大陆
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T101978,?9-?Epoxy-?3-?isobutyryloxy-?10-?(2-?methylbutanoyl)?thymol；8,9-环氧-3-异丁酰-10-(2-甲基丁酰) 百里草酚8-9-epoxy
8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol is a chemical composition of essential oils from Telekia speciosa. It also shows marked antipro-liferative activity against human cancer cell lines in vitro.
价 格：￥电议型 号：T10197产 地：中国大陆
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T10191L7-Chlorokynurenic acid；7-氯犬尿酸7-chloro-4-hydroxy-2-carboxyquinoline|||7-CKA；7-chloro-4-hydroxy-2-carb
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
价 格：￥电议型 号：T10191L产 地：中国大陆
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T101886RK73；化合物6RK736RK73
6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 ?M). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 ?M).
价 格：￥电议型 号：T10188产 地：中国大陆
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T101806-Alpha Naloxol；化合物 T10180Alpha-Naloxol；Alpha-Naloxol
6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist and is a human metabolite of naloxone.
价 格：￥电议型 号：T10180产 地：中国大陆
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T101685-HT1A modulator 1；化合物5-HT1A modulator 15-HT1Amodulator1；5-HT1Amodulator1
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
价 格：￥电议型 号：T10168产 地：中国大陆
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T101675-Dehydroepisterol；化合物 T101675-Dehydroepisterol
5-Dehydroepisterol is an episterol derivative with anti-fungal activities. It can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase.
价 格：￥电议型 号：T10167产 地：中国大陆
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T10165L5-A-RU hydrochloride；5-A-RU 盐酸盐5-Amino-6-(D-ribitylamino)uracil hydrochloride；5-Amino-6-(D-ribitylam
5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is an intermediate of bacterial riboflavin that activates mucosal-associated invariant T cells (MAIT).5-A-RU is used in the study of breast and prostate cancer.
价 格：￥电议型 号：T10165L产 地：中国大陆
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T101655-A-RU；化合物 T101655-Amino-6-(D-ribitylamino)uracil；5-Amino-6-(D-ribitylamino)uracil
5-A-RU (5-Amino-6-(D-ribitylamino)uracil), a precursor of bacterial Riboflavin, is a mucosal-associated invariant T (MAIT) cells activator. 5-A-RU forms potent MAIT-activating antigens via non-enzymatic reactions with small molecules that are derived from other metabolic pathways.
价 格：￥电议型 号：T10165产 地：中国大陆
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T1015842-(2-Tetrazolyl)rapamycin；化合物 T1015842-(2-Tetrazolyl)rapamycin
42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog.
价 格：￥电议型 号：T10158产 地：中国大陆
