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TN7083Ternatumoside IITernatumoside II
Ternatumoside II is a aqueous extract of Bauhinia megalandra leaves inhibits GIA
价 格:¥电议型 号:TN7083产 地:中国大陆
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T6535Histamine PhosphateHistamine,inhibit,Inhibitor,Histamine Phosphate,Histamine Receptor
Histamine acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.
价 格:¥电议型 号:T6535产 地:中国大陆
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TCS1704Artemitininhibit,Artemitin,Inhibitor
1. Artemetin has anti-inflammatory activity. 2. Artemetin protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1/2 and Akt. 3. Intravenous injection of Artemetin (.75 mg/kg) significantly reduces the hypertensive response to angiotensin I while increases the average length of bradykinin-induced hypotension.
价 格:¥电议型 号:TCS1704产 地:中国大陆
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TN1054Loureirin Cinhibit,Loureirin C,Inhibitor
Loureirin C can inhibit the activities of thrombin in vitro effectively.
价 格:¥电议型 号:TN1054产 地:中国大陆
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T6602Naratriptan hydrochlorideNaratriptan hydrochloride,Inhibitor,GR-85548A,Naratriptan,5-HT Receptor,5-h
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulatio
价 格:¥电议型 号:T6602产 地:中国大陆
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T9218AndrograpaninInhibitor,chemotaxis,p38 MAPK,leukocyte,SDF-1α,Andrograpanin,PBL,inhibit,Jurkat,anti-in
Andrograpanin is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
价 格:¥电议型 号:T9218产 地:中国大陆
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T21714BMS453Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X
BMS453, a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
价 格:¥电议型 号:T21714产 地:中国大陆
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T6S0119DauricineNuclear factor-κB,Inhibitor,inhibit,Dauricine,Nuclear factor-kappaB,Apoptosis,NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profil
价 格:¥电议型 号:T6S0119产 地:中国大陆
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T10773CF53CF-53,CF53
CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo.
价 格:¥电议型 号:T10773产 地:中国大陆
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T21996Zoniporide hydrochloride
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride shows an IC50 of 59 nM for NHE-1-dependent swelling of human platelets.
价 格:¥电议型 号:T21996产 地:中国大陆
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T67729UCM-1306UCM1036
UCM-1306 is a potent and orally active allosteric modulator (PAM) of human dopamine D1 receptor. UCM-1306 could increase the maximal effect of endogenous dopamine (DA) both in human and mouse D1 receptors. UCM-1306 could improve motor symptoms and address the key comorbid cognitive impairment associated with long-term Parkinson’s disease (PD).
价 格:¥电议型 号:T67729产 地:中国大陆
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T23439TC-N 1752TCN 1752,TC N 1752
TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.
价 格:¥电议型 号:T23439产 地:中国大陆
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T9461AZ194nociceptive neurotransmission,Inhibitor,CRMP2-Ubc9 interaction,Na+ channels,Na channels,inhibit
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
价 格:¥电议型 号:T9461产 地:中国大陆
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TP1543LG280-9 acetate(156761-76-1 free base)G280 9 acetate(156761 76 1 free base),G-280-9 acetate(156761-76
G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may be attributable to relatively low affinity of this peptide for the HLA-A2.
价 格:¥电议型 号:TP1543L产 地:中国大陆
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T98967-Methoxy-1-naphthylacetonitrile7Methoxy1naphthylacetonitrile,7 Methoxy 1 naphthylacetonitrile
7-Methoxy-1-naphthylacetonitrile is one of the impurities of agomelatine, an antidepressant.
价 格:¥电议型 号:T9896产 地:中国大陆
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TN1524Continentalic acidContinentalic acid,Bacterial,inhibit,Inhibitor
Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 ?g/mL against S. aureus, including the Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin susceptible Staphylococcus aureus (MSSA) and standard strains.
价 格:¥电议型 号:TN1524产 地:中国大陆
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TN7168Farnesylacetone
(5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one is a marine derived natural products found in Sargassum micracanthum.
价 格:¥电议型 号:TN7168产 地:中国大陆
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T6S1371Isovitexininhibit,Isovitexin,Nuclear factor-kappaB,Inhibitor,Nuclear factor-κB,NF-κB,JNK
1. Isovitexin exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.
价 格:¥电议型 号:T6S1371产 地:中国大陆
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TN1693GlabronePPAR,Peroxisome proliferator-activated receptors,Glabrone,inhibit,Inhibitor
Glabrone shows antiviral activity against influenza virus.
价 格:¥电议型 号:TN1693产 地:中国大陆