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T17243VU0463271；化合物VU0463271N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetami
VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide) is a potent and selective antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2), with an IC50 of 61 nM and >100-fold selectivity versus the closely related Na-K-2Cl cotransporter 1 (NKCC1) and no activity in a larger panel of GPCRs, ion channels, and transporters.
价 格：￥电议型 号：T17243产 地：中国大陆
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T17064-Hydroxy-3-nitrophenylacetic acid；4-羟基-3-硝基苯乙酸4-Hydroxy-3-nitrophenylacetic acid
4-Hydroxy-3-nitrophenylacetic acid is a small molecular drug, active in Ig heavy chain V-I region and Ig gamma-2 chain C region.
价 格：￥电议型 号：T1706产 地：中国大陆
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T1701H-ASP-PHE-OH；硫胺杂质BAspartyl-phenylalanine|||Demethylaspartame；Aspartyl-phenylalanine|||硫胺杂质B|||Demeth
H-ASP-PHE-OH (Aspartyl-phenylalanine) is used as pharmaceutical intermediates
价 格：￥电议型 号：T1701产 地：中国大陆
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T16923-(3,4-Dimethoxyphenyl)propanoic acid；3-(3,4-二甲氧基苯)丙酸3,4-Dimethoxyhydrocinnamic acid；3,4-Dimethoxyhy
3-(3,4-Dimethoxyphenyl)propanoic acid (3,4-Dimethoxyhydrocinnamic acid) is an orally active short-chain fatty acid (SCFAs). It promotes γ-globin gene expression and erythropoiesis in vivo and can be used in beta hemoglobinopathies and other anemias.
价 格：￥电议型 号：T1692产 地：中国大陆
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T1689Enalapril IMpurity B；依那普利杂质B(+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine；(+)-N-[1-(S)-Etho
Enalapril IMpurity B ((+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine) is Moexipril intermediate and is the main metabolite of Imidapril.
价 格：￥电议型 号：T1689产 地：中国大陆
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T16688Pyr6；化合物Pyr6N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide；N-
Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).Pyr6 is an inhibitor of Ca2+ entry, which displays higher potency to inhibit Ca2+ entry mediated by CRAC channel than by TRPC3.
价 格：￥电议型 号：T16688产 地：中国大陆
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T16613Propargyl-PEG4-5-nitrophenyl carbonate；化合物 T16613Propargyl-PEG4-5-nitrophenyl carbonate
Propargyl-PEG4-5-nitrophenyl carbonate is a polyethylene glycol (PEG) derivative specifically designed as a linker for proteolysis targeting chimeras (PROTACs) synthesis[1].
价 格：￥电议型 号：T16613产 地：中国大陆
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T16516PG01；化合物PG01Phenylglycine-01；Phenylglycine-01
PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively.PG01 increases ΔF508-CFTR Cl- currents upon addition of forskolin. F508-CFTR Cl-current upon addition of Forskolin, correcting the gating defect of CFTR mutants.
价 格：￥电议型 号：T16516产 地：中国大陆
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T16442PCO371；化合物PCO3712,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor.
价 格：￥电议型 号：T16442产 地：中国大陆
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T16345NS13001；化合物NS13001N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine|||N-(4-Chlor
NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias.
价 格：￥电议型 号：T16345产 地：中国大陆
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T16166N-[(4-Aminophenyl)methyl]adenosine；N-[(4-氨基苯基)甲基]腺苷N-[(4-Aminophenyl)methyl]adenosine
N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5′-Nucleotidase).
价 格：￥电议型 号：T16166产 地：中国大陆
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T16164MY-5445；化合物MY-5445N-(3-chlorophenyl)-4-phenylphthalazin-1-amine；N-(3-chlorophenyl)-4-phenylphthalazi
MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5). MY-5445 selectively inhibits cGMP PDE (Ki:1.3 μM).
价 格：￥电议型 号：T16164产 地：中国大陆
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T15919m-PEG7-4-nitrophenyl carbonate；化合物m-PEG7-4-nitrophenyl carbonatem-PEG7-4-nitrophenyl carbonate
m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
价 格：￥电议型 号：T15919产 地：中国大陆
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T15840m-PEG2-4-nitrophenyl carbonate；化合物 T15840m-PEG2-4-nitrophenyl carbonate
m-PEG2-4-nitrophenyl carbonate is a PEG-derived linker for PROTACs synthesis[1].
价 格：￥电议型 号：T15840产 地：中国大陆
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T15686L-741626；化合物L-7416263-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole；3-(4-(4-Chlorophenyl-4-hy
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively).
价 格：￥电议型 号：T15686产 地：中国大陆
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T15393Glycerol phenylbutyrate；苯丁酸甘油酯HPN-100；苯丁酸甘油酯|||HPN-100
Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
价 格：￥电议型 号：T15393产 地：中国大陆
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T15372GB1107；化合物GB1107(2R,3R,4S,5R,6R)-2-(3,4-dichlorophenyl)sulfanyl-6-(hydroxymethyl)-4-[4-(3,4,5-triflu
GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.
价 格：￥电议型 号：T15372产 地：中国大陆
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T1535Sodium 4-phenylbutyrate；苯丁酸钠Sodium Phenylbutyrate|||Buphenyl|||TriButyrate；苯丁酸钠|||Sodium Phenylbutyr
Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II histone deacetylases (HDACs )resulting in a global increase in gene expression, decreased cellular proliferation, increased cell differentiation, and the induction of apoptosis in susceptible tumor cell populations.
价 格：￥电议型 号：T1535产 地：中国大陆
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T15257LMethyl 3-[2-[[(4R)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]methylamino]ethyl]benzoate；化合物T1525
Methyl 3-[2-[[(4R)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]methylamino]ethyl]benzoate is a biochemical reagent that can be used to synthesize active compounds.
价 格：￥电议型 号：T15257L产 地：中国大陆
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T15160Dotinurad；化合物Dotinurad(3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone；(
Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).
价 格：￥电议型 号：T15160产 地：中国大陆
