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T64277ODN 1585；化合物 ODN 1585ODN 1585
ODN 1585 is a potent inducer of IFN and TNFα production, a potent stimulator of NK (natural killer) and can be used as a vaccine adjuvant.ODN 1585 enhances the function of CD8+ T cells, including CD8+ T cell-mediated IFN-γ production.ODN 1585 induces regression of established melanomas in mice and has been shown to inhibit malaria in mice. ODN 1585 can be used to study acute myelogenous leukaemia (AML) and malaria.
价 格：￥电议型 号：T64277产 地：中国大陆
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T64258gamma-secretase modulator 5；化合物 gamma-secretase modulator 5gamma-secretase modulator 5
gamma-secretase modulator 5 (compound 22d) is a gamma-secretase modulator (GSMs) that crosses the blood-brain barrier and exhibits an inhibitory effect on the production of the aggregated amyloid β peptide Aβ42 (IC50: 60 nM). gamma-secretase modulator 5 can be used in the study of Alzheimer´s disease. The gamma-secretase modulator 5 can be used to study Alzheimer´s disease.
价 格：￥电议型 号：T64258产 地：中国大陆
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T64158Nenocorilant；化合物 NenocorilantNenocorilant
Nenocorilant (Relacorilant) is an orally active glucocorticoid receptor (GR) antagonist (Ki: 0.15 nM). Nenocorilant can be used to study tumours.
价 格：￥电议型 号：T64158产 地：中国大陆
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T64058PLK1/BRD4-IN-1；化合物 PLK1/BRD4-IN-1PLK1/BRD4-IN-1
PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM). It has been shown to have good anti-tumour effects in vivo.
价 格：￥电议型 号：T64058产 地：中国大陆
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T64014Antitumor agent-58；化合物 Antitumor agent-58Antitumor agent-58
Antitumor agent-58 is an antitumour agent that effectively inhibits colony formation and cell migration in MGC-803 cells and induces mitochondrial dysfunction in MGC-803 cells. Antitumor agent-58 exhibited potent inhibitory activity against tumour growth in xenograft models carrying MGC-803 cells.
价 格：￥电议型 号：T64014产 地：中国大陆
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T63984PF-3758309 dihydrochloride；化合物 PF-3758309 dihydrochloridePF-3758309 dihydrochloride
PF-3758309 dihydrochloride is a potent, reversible, orally active, ATP-competitive PAK4 inhibitor with a Kd value of 2.7 nM and a Ki value of 18.7 nM. PF-3758309 dihydrochloride exhibits the expected cellular functions of a PAK4 inhibitor, with the ability to inhibit anchorage independent growth, induction of apoptosis, cytoskeletal remodelling and inhibition of proliferation.
价 格：￥电议型 号：T63984产 地：中国大陆
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T63968AZ14145845；化合物 AZ14145845AZ14145845
AZ14145845 is an in vivo potent and highly selective type I1/2 Mer/Axl bispecific kinase inhibitor.
价 格：￥电议型 号：T63968产 地：中国大陆
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T63936GSK5852；化合物 GSK5852GSK5852
GSK5852 (GSK2485852) is an HCV NS5B RdRp polymerase inhibitor. GSK5852 inhibits NS5B (IC50: 50 nM). GSK5852 exhibits antiviral effects against hepatitis C virus (HCV) with EC50 values of 3.0 nM for GT1a and 1.7 nM for GT1b.
价 格：￥电议型 号：T63936产 地：中国大陆
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T63858I-BET282E；化合物 I-BET282EI-BET282E
I-BET282E is a pan-inhibitor of eight BET bromodomains and shows selectivity for other representative bromodomain-containing proteins. i-BET282E is able to act on eight BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), BRD4 (BD1/BD) with their pIC50 values were 6.4-7.7.
价 格：￥电议型 号：T63858产 地：中国大陆
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T6378AMG-458；化合物AMG458AMG 458；AMG 458
AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
价 格：￥电议型 号：T6378产 地：中国大陆
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T63774EGFR-IN-58；化合物 EGFR-IN-58EGFR-IN-58
EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.
价 格：￥电议型 号：T63774产 地：中国大陆
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T63758G12Si-1；化合物 G12Si-1G12Si-1
G12Si-1 is a selective, covalent K-Ras(G12S) inhibitor that inhibits K-Ras(G12S) oncogenic signaling. On mutant serine residues, G12Si-1 binds K-Ras(G12S) well.G12Si-1 may also be able to impede Sos-catalyzed exchange and inhibit EDTA-facilitated exchange rates, thereby affecting the nucleotide cycle of K-Ras.
价 格：￥电议型 号：T63758产 地：中国大陆
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T63701TP-5801；化合物 TP-5801TP-5801
TP-5801 is an orally active non-receptor tyrosine kinase (TNK1) inhibitor with an IC50 value of 1.40 nM and antitumor effects.
价 格：￥电议型 号：T63701产 地：中国大陆
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T63658JAK-IN-18；化合物 JAK-IN-18JAK-IN-18
JAK-IN-18 is a potent inhibitor of JAK and can be used to study a variety of diseases, particularly eye, skin and respiratory diseases.
价 格：￥电议型 号：T63658产 地：中国大陆
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T63589CX-6258 hydrochloride hydrate；化合物 CX-6258 hydrochloride hydrateCX-6258 hydrochloride hydrate
CX-6258 hydrochloride hydrate is a potent and selective inhibitor of pan-Pim kinase that acts on Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM) and Pim-3 (IC50: 16 nM).
价 格：￥电议型 号：T63589产 地：中国大陆
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T63588Antibacterial agent 89；化合物 Antibacterial agent 89Antibacterial agent 89
Antibacterial agent 89 is a potent antibacterial agent that interferes with the process of bacterial transcription and exhibits anti-clostridial effects. antibacterial agent 89 inhibits the release of cytotoxins and β´CH-σ interactions.
价 格：￥电议型 号：T63588产 地：中国大陆
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T63587Anticancer agent 45；化合物 Anticancer agent 45Anticancer agent 45
Anticancer agent 46 is a potent and selective anticancer agent that induces apoptosis. anticancer agent 46 exhibits cytotoxic effects in cancer cells and shows low toxicity to activated lymphocytes of human blood.
价 格：￥电议型 号：T63587产 地：中国大陆
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T63586Zika virus-IN-1；化合物 Zika virus-IN-1Zika virus-IN-1
Zika virus-IN-1 is an inhibitor of Zika virus (EC50: 1.56 μM).
价 格：￥电议型 号：T63586产 地：中国大陆
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T63585HCV-IN-37；化合物 HCV-IN-37HCV-IN-37
HCV-IN-37 is a potent inhibitor of HCV. HCV-IN-37 is able to persist in rat plasma after oral administration to rats at a single dose of 15 mg/kg. The high potency of the active derivative HCV-IN-37 is mainly driven by the inhibition of the entry phase of the virus.
价 格：￥电议型 号：T63585产 地：中国大陆
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T63584ATX inhibitor 12；化合物 ATX inhibitor 12ATX inhibitor 12
ATX inhibitor 12 is an orally active ATX inhibitor (IC50: 1.72 nM). In C57Bl/6J mice, oral administration of ATX inhibitor 12 at a dose of 60 mg/kg was effective in inhibiting structural lung damage and reducing fibrotic lesions.
价 格：￥电议型 号：T63584产 地：中国大陆
