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T190932,3,4,5-Tetracaffeoyl-D-Glucaric acid;2,3,4,5-四咖啡酰-D-葡糖二酸2,3,4,5-Tetracaffeoyl-D-Glucaric acid
2,3,4,5-Tetracaffeoyl-D-Glucaric acid, a derivative of caffeoyl-D-glucaric acid, has been isolated from Inula japonica Thunb.
价 格:¥电议型 号:T19093产 地:中国大陆
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T1904SGI-1027;化合物SGI-1027DNA Methyltransferase Inhibitor II|||SGI1027;DNA Methyltransferase Inhibitor II|
SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.
价 格:¥电议型 号:T1904产 地:中国大陆
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T1903Dabrafenib;达拉非尼GSK2118436A|||GSK2118436;GSK2118436A|||GSK2118436|||达拉非尼
Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5/0.6 nM) and is ATP-competitive. Dabrafenib exhibits antitumor activity for the treatment of B-RafV600E-mutated melanoma.
价 格:¥电议型 号:T1903产 地:中国大陆
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T188884-Methylumbelliferyl phosphate;4-甲基伞形酮磷酸酯4-MUP;4-甲基伞形酮磷酸酯|||4-MUP
4-Methylumbelliferyl phosphate (4-MUP) (4-MUP) is used as a fluorogenic substrate of alkaline phosphatases.
价 格:¥电议型 号:T18888产 地:中国大陆
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T188874-Methylumbelliferyl-β-D-glucuronide hydrate4-甲基伞形酮-Β-D-葡糖苷酸二水合物4-甲基伞形酮-Β-D-葡糖苷酸二水合物|||MUG
4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrat (λex=362 nm , λem=445 nm).
价 格:¥电议型 号:T18887产 地:中国大陆
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T1872Fenretinide;芬维A胺4-HPR|||MK-4016|||4-hydroxy(phenyl)retinamide;4-HPR|||MK-4016|||芬维A胺|||4-hydroxy(phe
Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.
价 格:¥电议型 号:T1872产 地:中国大陆
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T1792LRegorafenib monohydrate;瑞格非尼一水合物Regorafenib monohydrate
Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively.
价 格:¥电议型 号:T1792L产 地:中国大陆
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T1792Regorafenib;瑞戈非尼BAY 73-4506|||Fluoro-Sorafenib;BAY 73-4506|||瑞戈非尼|||Fluoro-Sorafenib|||瑞格非尼
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity.
价 格:¥电议型 号:T1792产 地:中国大陆
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T17731CL2A-SN-38;化合物CL2A-SN-38CL2A|||CL2A SN 38|||bystander effect|||SN-38|||antitumor|||CL2A-SN-38|||Inhi
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a nonclaevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulf
价 格:¥电议型 号:T17731产 地:中国大陆
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T17309(R)-(-)-Ibuprofen;(R)-(-)-布洛芬levibuprofen|||(R)-Ibuprofen;levibuprofen|||(R)-Ibuprofen
(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects.
价 格:¥电议型 号:T17309产 地:中国大陆
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T17306(R)-Baclofen hydrochloride;(R)-巴氯芬盐酸盐Arbaclofen hydrochloride;Arbaclofen hydrochloride|||(R)-巴氯芬盐酸盐
Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to spinal cord damage. It acts at spinal and supraspinal sites, generally reduces excitatory transmission.
价 格:¥电议型 号:T17306产 地:中国大陆
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T17283Zamifenacin;化合物 T17283UK-76654;UK-76654
Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.
价 格:¥电议型 号:T17283产 地:中国大陆
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T1720LAmfenac;化合物 T1720LNSC309467|||NSC-309467|||NSC 309467;NSC309467|||NSC-309467|||NSC 309467
Amfenac promotes apoptosis in ARPE-19 cell culture.
价 格:¥电议型 号:T1720L产 地:中国大陆
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T1720Amfenac Sodium Hydrate;氨芬酸钠水合物Amfenac Sodium Monohydrate;一水氨芬酸钠|||Amfenac Sodium Monohydrate|||氨芬酸钠水
Amfenac Sodium Hydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety.
价 格:¥电议型 号:T1720产 地:中国大陆
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T17094Tifenazoxide化合物 T17094NN414
Tifenazoxide is an effective and SUR1/Kir6.2 selective KATP channels opener. Tifenazoxide has an anti-diabetic effect, can inhibit glucose-stimulated insulin release in vitro and in vivo.
价 格:¥电议型 号:T17094产 地:中国大陆
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T16990Tarafenacin;化合物 T16990SVT-40776;SVT-40776
Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.
价 格:¥电议型 号:T16990产 地:中国大陆
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T16989Tarafenacin D-tartrate;Tarafenacin D-酒石酸盐SVT-40776 D-tartrate;SVT-40776 D-tartrate
Tarafenacin D-tartrate (SVT-40776 D-tartrate) is a selective and potent muscarinic acetylcholine M3 receptor antagonist used in the study of overactive bladder and bronchial disorders.
价 格:¥电议型 号:T16989产 地:中国大陆
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T16948Suclofenide;琥氯非尼PB385|||Neosulfalepsine;PB385|||Neosulfalepsine|||琥氯非尼
Suclofenide is a benzenesulfonamide derivative that acts as an anticonvulsant and antiepileptic agent. In preclinical models, it showed potent anticonvulsant activity against electroshock and pentylenetetrazole-induced convulsions in mice. Sublethal toxicity was demonstrated by lethargy, myoclonic jerks and diarrhea.
价 格:¥电议型 号:T16948产 地:中国大陆
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T1693Umbelliferone;7-羟基香豆素Skimmetine|||Hydrangin|||Hydrangine|||7-Hydroxycoumarin|||NSC 19790;Skimmetine|
Umbelliferone (7-Hydroxycoumarin) is found in anise. Umbelliferone occurs widely in plants including Angelica species Phytoalexin of infected sweet potat. It has been reported to have antioxidant properties.
价 格:¥电议型 号:T1693产 地:中国大陆
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T16909Donafenib;多纳非尼Sorafenib (D3)|||Bay 43-9006 (D3)|||Sorafenib-d3;Sorafenib (D3)|||Bay 43-9006 (D3)|||S
Donafenib (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
价 格:¥电议型 号:T16909产 地:中国大陆