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T24006Zolertine HCl;化合物 T24006Zolertine HCl
Zolertine HCl is an antagonist of alpha-Adrenoceptor.
价 格:¥电议型 号:T24006产 地:中国大陆
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T24001Diisopropyl tartrate;化合物 T24001Diisopropyl (+)-L-tartrate|||L-DIPT|||BRN 1727863;Diisopropyl (+)-L-t
Diisopropyl tartrate is a reagent for kinetic resolution of racemic allylic alcohols and α-furfuryl amides. It acts by enantioselective epoxidation.
价 格:¥电议型 号:T24001产 地:中国大陆
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T2400Candesartan Cilexetil;坎地沙坦酯TCV-116;TCV-116|||坎地沙坦酯|||坎地沙坦西酯
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with angiotensin II for the binding of the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation.
价 格:¥电议型 号:T2400产 地:中国大陆
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T2399Bortezomib;硼替佐米Radiciol|||NSC 681239|||MG 341|||DPBA|||Brotezamide|||LDP 341;Radiciol|||NSC 681239||
Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-κB, which can disrupt the cell cycle and induce apoptosis.
价 格:¥电议型 号:T2399产 地:中国大陆
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T23975Deacylcortivazol;化合物 T23975UNII-3JO09QT49F|||DAC|||NSC 325316;UNII-3JO09QT49F|||DAC|||NSC 325316
Deacylcortivazol (DAC) is a potent glucocorticoid. When incubated with glucocorticoid-resistant mutants derived from the glucocorticoid-sensitive human leukemic cell line CEM-C7, DAC caused significant growth inhibition. The cytotoxicity of DAC at concentrations higher than necessary for glucocorticoid receptor saturation is not mediated by glucocorticoid receptors.
价 格:¥电议型 号:T23975产 地:中国大陆
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T2395LVortioxetine hydrobromide;盐酸沃替西汀Vortioxetine (Lu AA21004) HBr|||Vortioxetine HBr|||Lu AA21004 hydrob
Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
价 格:¥电议型 号:T2395L产 地:中国大陆
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T2395Vortioxetine;沃替西汀Lu AA 21004;沃替西汀|||Lu AA 21004
Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.
价 格:¥电议型 号:T2395产 地:中国大陆
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T23917CRT-0105950;化合物 T23917CRT 0105950;CRT 0105950
CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.
价 格:¥电议型 号:T23917产 地:中国大陆
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T23916CRT-0105446;化合物 T23916CRT0105446;CRT0105446
CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.
价 格:¥电议型 号:T23916产 地:中国大陆
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T23915CRT0093964;化合物 T23915CRT-0093964|||CRT 0093964;CRT-0093964|||CRT 0093964
CRT0093964 is a selective AKR1C3 inhibitor.
价 格:¥电议型 号:T23915产 地:中国大陆
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T23914CRT0083914;化合物 T23914CRT-0083914|||CRT 0083914;CRT-0083914|||CRT 0083914
CRT0083914 is a potent and selective AKR1C3 inhibitor.
价 格:¥电议型 号:T23914产 地:中国大陆
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T23909Cortistatin A;化合物 T23909Cortistatin-A;Cortistatin-A
Cortistatin A is a potent and selective mediator-associated kinase CDK8 and its paralogue CDK19 inhibitor.
价 格:¥电议型 号:T23909产 地:中国大陆
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T23879Chartreusin;化合物 T23879NSC5159|||NSC 5159|||NSC-5159;NSC5159|||NSC 5159|||NSC-5159
Chartreusin is an antibiotic. It also has anticancer activity.
价 格:¥电议型 号:T23879产 地:中国大陆
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T23796BIRT-377;化合物BIRT-377BIRT377|||BIRT 377;BIRT377|||BIRT 377
BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1(Ki = 25.8 nM). BIRT-377 inhibits the production of IL-2 and can be used in studies about inflammatory and immune disorders.
价 格:¥电议型 号:T23796产 地:中国大陆
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T23783Benzoxonium chloride;化合物 T23783Bradophen|||Bialcol|||D 301|||D301|||Cohortan;Bradophen|||Bialcol|||D
Benzoxonium chloride, The topical treatment of anthroponotic cutaneous leishmaniasis with the tincture of thioxolone plus benzoxonium chloride (Thio-Ben) along with cryotherapy.
价 格:¥电议型 号:T23783产 地:中国大陆
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T2358LENMD-2076 tartrate;化合物 T2358LENMD-2076|||L-(+) Tartrate salt of ENMD-981693|||ENMD2076|||ENMD 2076;E
ENMD-2076 is an orally active kinase inhibitor. It also has antiangiogenic and antiproliferative mechanisms of action.
价 格:¥电议型 号:T2358L产 地:中国大陆
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T23457threo Ifenprodil hemitartrate;化合物 T23457threo Ifenprodil hemitartrate
σ receptor agonist and NR2B subunit-selective NMDA receptor antagonist
价 格:¥电议型 号:T23457产 地:中国大陆
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T23357SIRT1/2 Inhibitor IV;化合物 T23357SIRT1/2 Inhibitor IV
SIRT1/2 Inhibitor IV (cannabinol) is a small-molecule inhibitor of SIRT1 and SIRT2 with IC50 values of 56 μM and 59 μM, respectively.
价 格:¥电议型 号:T23357产 地:中国大陆
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T23228(R,S)-Anatabine (tartrate) (2743-90-0 free base);化合物 T23228(R,S)-Anatabine (tartrate);(R,S)-Anatabin
Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tartrate) is preferable to (R,S)-Anatabine for certain applications and formulations.
价 格:¥电议型 号:T23228产 地:中国大陆
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T2322Fimasartan;非马沙坦BR-A-657|||Kanarb;非马沙坦|||BR-A-657|||Kanarb
Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has shown to be safe in clinical trials.
价 格:¥电议型 号:T2322产 地:中国大陆