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T22698TLR3-IN-1；化合物CU CPT 4aCU CPT 4a；CU CPT 4a
TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cells.
价 格：￥电议型 号：T22698产 地：中国大陆
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T2246LRRK2-IN-1化合物LRRK2-IN-15,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]羰基]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-B][1
LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.
价 格：￥电议型 号：T2246产 地：中国大陆
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T21700NOS-IN-1u00A0；化合物NOS-IN-1u00A02-Imino-4-methylpiperidine (acetate)；2-Imino-4-methylpiperidine (aceta
NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectively.
价 格：￥电议型 号：T21700产 地：中国大陆
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T2082CDK4-IN-1；化合物CDK4-IN-1CDK4-IN-1
CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50=5.265 uM) respectively.
价 格：￥电议型 号：T2082产 地：中国大陆
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T20513IDO1-IN-12-肼基苯并噻唑IDO1 inhibitor 1|||2 HzBTZ|||2-肼基苯并噻唑|||IDO1IN1|||2-HzBTZ|||IDO1-inhibitor-1
IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.
价 格：￥电议型 号：T20513产 地：中国大陆
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T2051SKLB4771；化合物FLT3-IN-1FLT3-?IN-?1|||FLT3-IN-1；FLT3-?IN-?1|||FLT3-IN-1
SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.
价 格：￥电议型 号：T2051产 地：中国大陆
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T19206β-Lactamase-IN-1；化合物β-Lactamase-IN-14-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one
β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.
价 格：￥电议型 号：T19206产 地：中国大陆
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T1842XMD17-109；化合物XMD17-109XMD17 109|||ERK5-IN-1；XMD17 109|||ERK5-IN-1
XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).
价 格：￥电议型 号：T1842产 地：中国大陆
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T1826PI3K-IN-1；化合物Voxtalisib AnalogueVoxtalisib Analogue|||Voxtalisib (SAR245409, XL765) Analogue|||XL765
PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.
价 格：￥电议型 号：T1826产 地：中国大陆
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T17697BRD7-IN-1；化合物BRD7-IN-1BRD7-IN-1
BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 through linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively [1].
价 格：￥电议型 号：T17697产 地：中国大陆
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T17696BRD7-IN-1 free base；化合物 T17696BRD7-IN-1 free base
BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), interacts with a VHL ligand through a linker, constituting the PROTAC VZ185 (targeting BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively)[1].
价 格：￥电议型 号：T17696产 地：中国大陆
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T16944STK16-IN-1；化合物STK16-IN-1STK16-IN-1
STK16-IN-1 is an inhibitor of STK16 kinase (IC50: 295 nM).
价 格：￥电议型 号：T16944产 地：中国大陆
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T16795Rpn11-IN-1；化合物 T16795Capzimin intermediate；Capzimin intermediate
Rpn11-IN-1 is an effective and selective inhibitor of proteasome subunit Rpn11 (IC50: 390 nM).
价 格：￥电议型 号：T16795产 地：中国大陆
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T16735RET-IN-1；化合物 T16735RET-IN-1
RET-IN-1 is a RET kinase inhibitor (IC50s: 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively).
价 格：￥电议型 号：T16735产 地：中国大陆
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T16432Pan-RAS-IN-1；化合物Pan-RAS-IN-1Pan-RAS-IN-1
Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.
价 格：￥电议型 号：T16432产 地：中国大陆
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T16424p38 MAPK-IN-1；化合物 T16424p38 MAPK-IN-1
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
价 格：￥电议型 号：T16424产 地：中国大陆
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T16162Mutated EGFR-IN-1；AZD9291中间体1Osimertinib analog；Osimertinib analog|||AZD9291中间体1
Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
价 格：￥电议型 号：T16162产 地：中国大陆
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T16078Mirk-IN-1化合物 T16078Dyrk1B/A-IN-1
Mirk-IN-1 is an effective inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A (IC50: 68±48 nM and 22±8 nM respectively).
价 格：￥电议型 号：T16078产 地：中国大陆
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T16027Mcl1-IN-1；化合物 T16027Mcl1-IN-1
Mcl1-IN-1 is a myeloid cell factor 1 inhibitor (IC50=2.4 μM).
价 格：￥电议型 号：T16027产 地：中国大陆
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T16007MALAT1-IN-1；化合物MALAT1-IN-1MALAT1-IN-1
MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting the expression of nuclear enriched abundant transcript 1 (Neat1). MALAT1-IN-1 is an effective and specific Malat1 inhibitor.
价 格：￥电议型 号：T16007产 地：中国大陆
