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T6681STF-083010;化合物STF083010STF083010;STF083010
STF-083010 is a selective inhibitor of the IRE1α endonuclease.
价 格:¥电议型 号:T6681产 地:中国大陆
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T66083Dulcitol;化合物 DulcitolDulcitol
Dulcitol is a sugar alcohol and slightly sweet tastant for human taste cells.
价 格:¥电议型 号:T66083产 地:中国大陆
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T650832-Amino-2-methyl-3-phenylpropanoic acid;化合物 2-Amino-2-methyl-3-phenylpropanoic acid2-Amino-2-methyl-
2-Amino-2-methyl-3-phenylpropanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65083 and the CAS number is 1132-26-9.
价 格:¥电议型 号:T65083产 地:中国大陆
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T64083MMP-9-IN-5;化合物 MMP-9-IN-5MMP-9-IN-5
MMP-9-IN-5 is an MMP-9 inhibitor with an IC50 value of 4.49 nM and is able to form hydrogen bonds with MMP-9. MMP-9-IN-5 also inhibits AKT activity with an IC50 value of 1.34 nM. MMP-9-IN-5 exhibits cytotoxicity, induces apoptosis and can be used in cancer research.
价 格:¥电议型 号:T64083产 地:中国大陆
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T63083SOS1-IN-4;化合物 SOS1-IN-4SOS1-IN-4
SOS1-IN-4 is a potent inhibitor of SOS1 (IC50: 56 nM) and can be used in the study of KRAS-C12C/SOS1 interactions.
价 格:¥电议型 号:T63083产 地:中国大陆
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T62083Camonsertib;化合物CamonsertibATR inhibitor 4|||RP-3500;ATR inhibitor 4|||RP-3500
Camonsertib (RP-3500) is a selective, orally active ATR kinase inhibitor (ATRi) with an IC50: 1.00 nM in biochemical assays and exhibits potent antitumour effects. Camonsertib is 30 times more selective for ATR than mTOR (IC50: 120 nM) and is a more active inhibitor of ATM, DNA-PK and PI3Kα kinases. PK and PI3Kα kinases.
价 格:¥电议型 号:T62083产 地:中国大陆
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T61083DN-F01;化合物 DN-F01DN-F01
DN-F01 exhibits a potent calcium-dependent inhibitory effect on cardiac myofibrillar ATPase activity, with an IC50 of 11 ± 4 nmol/L.
价 格:¥电议型 号:T61083产 地:中国大陆
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T60839SLMP53-1;化合物 SLMP53-1SLMP53-1
SLMP53-1 is a p53 activator with anti-tumor activity, inhibits wt and mutp53, activates reprogramming of glucose metabolism in xenografted human tumor tissues, and interferes with angiogenesis and migration. SLMP53-1 inhibits tumor cell growth and can be used to study human rectal cancer.
价 格:¥电议型 号:T60839产 地:中国大陆
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T60838Gü2602;化合物 Gü2602Gü2602
Gü2602 inhibits the cathepsin K zymogen autocatalytic activation that is a potent, reversible inhibitor of cathepsin K (CatK) with a Ki of 0.013 nM for mature CatK (mCatK) [1].
价 格:¥电议型 号:T60838产 地:中国大陆
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T60837AChE/BuChE-IN-2;化合物 AChE/BuChE-IN-2AChE/BuChE-IN-2
AChE/BuChE-IN-2 (Compound 5f) can cross the BBB that is an orally active inhibitor of AChE and BuChE with IC 50 values of 0.72 μM and 0.16 μM, respectively. AChE/BuChE-IN-2 shows potent inhibition of self-induced β-amyloid (Aβ) aggregation with an IC 50 of 62.52 μM and a non-competitive inhibition with AChE [1].
价 格:¥电议型 号:T60837产 地:中国大陆
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T60836PT4;化合物 PT4PT4
PT4 is a treatment agent for Cutaneous leishmaniasis (CL). PT4 decreases of mitochondrial membrane potential and increases reactive oxygen species production, therefore leads to parasite death. PT4 is effective against both species of Leishmania. The IC50 values of PT4 against L. amazonensis and L. braziliensis are 125.18 and 233.18 μM , respectively. PT4 also shows potent anti-inflammatory activity in vivo [1].
价 格:¥电议型 号:T60836产 地:中国大陆
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T60835SKF83959;化合物SKF83959SKF83959
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent variant modulator of the sigma (σ)-1 receptor, which ameliorates cognitive dysfunction for the study depression and Alzheimer´s disease.
价 格:¥电议型 号:T60835产 地:中国大陆
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T60834Phentolamine hydrochloride;化合物 Phentolamine hydrochloridePhentolamine hydrochloride
Phentolamine hydrochloride is a blocking agent of adrenergic α receptor that is orally active [1].
价 格:¥电议型 号:T60834产 地:中国大陆
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T60833Mycobactin-IN-2;化合物 Mycobactin-IN-2Mycobactin-IN-2
Mycobactin-IN-2 (compound 49) is an inhibitor of mycobactin biosynthesis that binds to salicyl-AMP ligase (MbtA). MbtA is a key enzyme of mycobactin biosynthetic pathway [1].
价 格:¥电议型 号:T60833产 地:中国大陆
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T60832(S)-Bromoenol lactone;化合物 (S)-Bromoenol lactone(S)-Bromoenol lactone
(S)-Bromoenol lactone ((S)-BEL) inhibits the arachidonate release induced by vasopressin from cultured rat aortic smooth muscle (A10) cells with an IC 50 of 2 μM. (S)-Bromoenol lactone is an irreversible, chiral, mechanism-based calcium-independent phospholipase A2β (iPLA 2 β) inhibitor [1].
价 格:¥电议型 号:T60832产 地:中国大陆
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T60831AChE/BChE-IN-3 hydrochloride;化合物 AChE/BChE-IN-3 hydrochlorideAChE/BChE-IN-3 hydrochloride
AChE/BChE-IN-3 (BMC-1) hydrochloride is an AChE and BChE dual inhibitor. The IC50 values of AChE/BChE-IN-3 against equine serum BChE (eqBChE) and electric eel AChE (elAChE) is 0.383 μM and 6.08 μM, respectively [1].
价 格:¥电议型 号:T60831产 地:中国大陆
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T6083AZD8330;化合物AZD8330ARRY-424704|||ARRY-704;ARRY-424704|||ARRY-704
AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
价 格:¥电议型 号:T6083产 地:中国大陆
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T60083MMP-12 Inhibitor;化合物MMP-12MMP12|||MMP408;MMP12|||MMP408
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
价 格:¥电议型 号:T60083产 地:中国大陆
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T5S2083Puerarin 6’’-O-Xyloside;葛根素-6″-O-木糖苷Puerarin 6''-O-Xyloside
Puerarin 6´´-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 and Bax, and reduced levels Bcl-2.
价 格:¥电议型 号:T5S2083产 地:中国大陆
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T5S0836Isoastragaloside II;黄芪甲苷VIIAstrasieversianin VII;黄芪甲苷VII|||Astrasieversianin VII
Isoastragaloside II (Astrasieversianin VII) is a derivative Astragaloside I, an ingredient in Astragalus membranaceus which is reported to have osteogenic properties.
价 格:¥电议型 号:T5S0836产 地:中国大陆