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T80838WAY-271999;化合物 WAY-271999WAY-271999
WAY-271999 is an active molecule.
价 格:¥电议型 号:T80838产 地:中国大陆
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T80199LfcinB 17–28 TFA;化合物 LfcinB 17–28 TFALfcinB 17–28 TFA
LfcinB 17–28 TFA, a fragment of Bovine Lactoferricin (LfcinB), exhibits weak antimicrobial activity, with a minimum inhibitory concentration (MIC) of 200 μM against E. coli [1].
价 格:¥电议型 号:T80199产 地:中国大陆
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T79199F-CRI1;化合物 F-CRI1F-CRI1
F-CRI1, a potent STING agonist with a dissociation constant (K d) of 40.62 nM, is an 18F-labeled radioactive probe employed for visualizing STING in the tumor microenvironment [1].
价 格:¥电议型 号:T79199产 地:中国大陆
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T78557HOIPIN-1;化合物JTP0819958JTP0819958;JTP0819958
HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-kB activation.
价 格:¥电议型 号:T78557产 地:中国大陆
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T78199S07-1066;化合物 S07-1066S07-1066
S07-1066, an aldo-keto reductase 1C3 (AKR1C3) inhibitor, enhances doxorubicin (DOX) cytotoxicity by selectively inhibiting AKR1C3-mediated reduction of DOX and reversing DOX resistance in cells with elevated AKR1C3 expression [1].
价 格:¥电议型 号:T78199产 地:中国大陆
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T77813SG3199-Val-Ala-PAB;化合物 SG3199-Val-Ala-PABSG3199-Val-Ala-PAB
SG3199-Val-Ala-PAB is an intermediate in the synthesis of Tesirine, a conjugate of agent-linker for antibody-drug conjugates (ADCs), utilized in the research of various cancers [1].
价 格:¥电议型 号:T77813产 地:中国大陆
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T77615ND-011992;化合物ND-011992ND011992;ND011992
ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I. ND-011992 inhibits bo3 oxidase, bd-I oxidases and bd-II oxidases, ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I, bo3 oxidase, bd-I oxidases, and bd-II oxidases with IC50s of 0.12, 2.47, 0.63, and 1.3 μM, respectively.ND-011992 can be used in the study of tuberculosis.
价 格:¥电议型 号:T77615产 地:中国大陆
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T77520AOH1996;化合物AOH1996AOH1996
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and apoptosis.AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II.AOH1996 acts synergistically with DNA damaging agents to inhibit tumor ce
价 格:¥电议型 号:T77520产 地:中国大陆
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T77359Tezepelumab;替西伐单抗Tezepelumab-ekko|||MEDI 19929|||AMG 157;Tezepelumab-ekko|||MEDI 19929|||AMG 157
Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.
价 格:¥电议型 号:T77359产 地:中国大陆
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T77199Methionylserine;化合物 MethionylserineMethionylserine
Methionylserine (H-MET-SER-OH), a dipeptide composed of methionine and serine, demonstrates effective binding and translocation through the intestinal di/tri-peptide transporter 1 (hPEPT1), possessing a K_m value of 0.2 mM. It also exhibits inhibition of ACE enzyme activity, rendering it useful in hypertension research [1] [2].
价 格:¥电议型 号:T77199产 地:中国大陆
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T76199α-Synuclein (61-75) (TFA);化合物 α-Synuclein (61-75) (TFA)α-Synuclein (61-75) (TFA)
α-Synuclein (61-75) TFA is a fragment (residues 61-75) of the abundant neuronal protein α-Synuclein, which is predominantly located in presynaptic nerve terminals. α-Synuclein serves as a potential biomarker for Parkinson´s disease (PD) [1] [2].
价 格:¥电议型 号:T76199产 地:中国大陆
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T751995-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine;化合物 5-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-d
5-(2-Hydroxyethyl)-2´,3´-di-O-toluoyl-2´-deoxyuridine, a purine nucleoside analog, exhibits widespread antitumor activity specifically against indolent lymphoid malignancies. Its anticancer effects are primarily through the inhibition of DNA synthesis and the induction of apoptosis, among other mechanisms [1].
价 格:¥电议型 号:T75199产 地:中国大陆
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T74199Beauverolide Ka;化合物 Beauverolide KaBeauverolide Ka
Beauverolide Ka, a cyclotetradepsipeptide derived from the Beauveria bassiana fungus, enhances glucose absorption in rat L6 myoblasts cultured at a concentration of 50 μM and exhibits protective effects on HEI-OC1 cells at 10 μM. It demonstrates dose-dependent activities in both L6 myoblasts and myotubes [1] [2].
价 格:¥电议型 号:T74199产 地:中国大陆
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T72199Antiproliferative agent-10;化合物 Antiproliferative agent-10Antiproliferative agent-10
Antiproliferative Agent-10, a ruthenium(II)-tris-pyrazolylmethane complex, functions as an anti-tumor compound by impeding cancer cell growth through the inhibition of mitochondrial calcium uptake.
价 格:¥电议型 号:T72199产 地:中国大陆
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T71999ZINC09410451;化合物 ZINC09410451ZINC09410451
ZINC09410451 is a potent ebolavirus (EBOV) inhibitor.
价 格:¥电议型 号:T71999产 地:中国大陆
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T71998673-A;化合物 673-A673-A
673-A is an aldehyde dehydrogenase (ALDH1A) inhibitor that depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines. 673-A triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP). 673-A also overcomes chemotherapy resistance in vivo.
价 格:¥电议型 号:T71998产 地:中国大陆
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T71997CypD-IN-29;化合物 CypD-IN-29CypD-IN-29
CypD-IN-29 is a non-peptidic inhibitor of cyclophilin D as a neuroprotective agent in Aβ-induced mitochondrial dysfunction.
价 格:¥电议型 号:T71997产 地:中国大陆
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T71996VU0621623;化合物 VU0621623VU0621623
VU0621623 is an arenavirus multiplication inhibitor which blocks lymphocytic choriomeningitis virus (LCMV) cell entry.
价 格:¥电议型 号:T71996产 地:中国大陆
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T71995Decanoyl chloride;化合物 Decanoyl chlorideDecanoyl chloride
Decanoyl Chloride is used in the synthesis of an effective metalloproteinase inhibitor. Also acts as a reagent in the synthesis of reversible α-ketoheterocycle inhibitors of fatty acid amide hydrolase as potnetial analgesics.
价 格:¥电议型 号:T71995产 地:中国大陆
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T71994Pyrithione Zinc;化合物 Pyrithione ZincPyrithione Zinc
Pyrithione Zinc is a novel KMD5A inhibitor.
价 格:¥电议型 号:T71994产 地:中国大陆