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T82264GPR34 receptor antagonist 3;化合物 GPR34 receptor antagonist 3GPR34 receptor antagonist 3
Compound 5e, a GPR34 receptor antagonist, exhibits selective inhibition of lysophosphatidylserine-induced ERK1/2 phosphorylation in a dose-dependent manner, demonstrating an IC50 value of 0.680 μM without significant cytotoxicity. Additionally, it displays antisensory activity in a mouse neuropathic pain model [1].
价 格:¥电议型 号:T82264产 地:中国大陆
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T82263GPR61 Inverse agonist 1;化合物 GPR61 Inverse agonist 1GPR61 Inverse agonist 1
Compound 1, identified as a GPR61 inverse agonist, exhibits an IC50 of 11 nM, rendering it suitable for metabolism and body weight disorder research, including obesity and cachexia [1].
价 格:¥电议型 号:T82263产 地:中国大陆
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T82262Grandivine A;化合物 Grandivine AGrandivine A
Grandivine A, a steroid alkaloid, has been isolated from Veratrum grandiflorum [1].
价 格:¥电议型 号:T82262产 地:中国大陆
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T82261Grb2 SH2 domain inhibitor 1;化合物 Grb2 SH2 domain inhibitor 1Grb2 SH2 domain inhibitor 1
Grb2 SH2 Domain Inhibitor 1 is a cyclic cell-penetrating peptide (CPP) featuring a conformationally restricted d-pro-l-pro motif ring (AF Φ Rpprrfq), where Φ represents L-naphthylalanine, R denotes D-arginine, and P indicates D-proline. This compound primarily functions as a cyclic peptide inhibitor.
价 格:¥电议型 号:T82261产 地:中国大陆
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T82260Grisnilimab;化合物 GrisnilimabWT1;WT1
"Grisnilimab (WT1), an IgG2a monoclonal antibody targeting CD7, acts as a tumor suppressor in the pathogenesis of Wilms´ tumor. It modulates the transcription of various genes and may be involved in post-transcriptional RNA processing [1]."
价 格:¥电议型 号:T82260产 地:中国大陆
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T8226Cue-lure;诱蝇酮Q-lure|||Pherocon (4-(4-Acetoxyphenyl)-2-butanone);Q-lure|||乙酸覆盆子酮酯|||诱蝇酮|||Pherocon (4-
Cue-lure (Pherocon (4-(4-Acetoxyphenyl)-2-butanone)) is a standard melon fly attractant
价 格:¥电议型 号:T8226产 地:中国大陆
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T82226HDAC6-IN-21;化合物 HDAC6-IN-21HDAC6-IN-21
HDAC6-IN-21 (compound 13) is an irreversible inhibitor of histone deacetylase 6 (HDAC6) [1].
价 格:¥电议型 号:T82226产 地:中国大陆
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T81226SAIRGA TFA;化合物 SAIRGA TFASAIRGA TFA
SAIRGA (TFA), a phi3T phage-derived agent, identifies phAimR within the bacterial cytosol to trigger lysogeny [1].
价 格:¥电议型 号:T81226产 地:中国大陆
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T80226r8 Bid BH3;化合物 r8 Bid BH3r8 Bid BH3
r8 Bid BH3, a biologically active peptide, is a pro-apoptotic member of the "BH3-only" subset within the BCL-2 family proteins, pivotal in regulating apoptosis. This compound exhibits lethality towards Bcl-2-expressing human leukemia cell lines, indicating its promise as a potential cancer therapeutic. The peptide is conjugated with poly-D-arginine (denoted by rrrrrrrr), enhancing cellular uptake.
价 格:¥电议型 号:T80226产 地:中国大陆
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T79226AMPK activator 11;化合物 AMPK activator 11AMPK activator 11
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative phosphorylation (OXPHOS) (mitochondrial metabolism). This compound demonstrates particular efficacy in inhibiting RKO xenograft growth, rendering it useful for anti-tumor and metabolic disease research [1].
价 格:¥电议型 号:T79226产 地:中国大陆
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T78226Methyl 2-amino-5-bromobenzoate;5-溴代邻氨基苯甲酸甲酯Methyl 5-Bromoanthranilate;Methyl 5-Bromoanthranilate
Methyl 2-amino-5-bromobenzoate (Methyl 5-Bromoanthranilate) is a hepatitis C virus NS5b RNA polymerase inhibitor with antimicrobial activity that inhibits Pseudomonas aeruginosa infections and is involved in the production of many virulence factors and biofilm formation.
价 格:¥电议型 号:T78226产 地:中国大陆
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T77226Basic Blue 20;化合物 Basic Blue 20Basic Blue 20
Basic Blue 20, a red-emitting DNA stain, exhibits relatively narrow excitation and emission spectra, peaking at 633 nm and 677 nm, respectively. Furthermore, it is characterized by its high resistance to photobleaching [1].
价 格:¥电议型 号:T77226产 地:中国大陆
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T7704KY-226;化合物KY-226KY-226
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)
价 格:¥电议型 号:T7704产 地:中国大陆
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T76747Fletikumab;夫来库单抗Anti-IL-20|||NN-8226|||NNC 0109-0012;Anti-IL-20|||NN-8226|||NNC 0109-0012
Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid arthritis and psoriasis.
价 格:¥电议型 号:T76747产 地:中国大陆
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T76226c[Arg-Arg-Arg-Arg-Nal-Nal-Nal];化合物 c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]
Compound 9C [c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]] demonstrates broad-spectrum efficacy against drug-resistant Gram-positive and Gram-negative bacteria. It exhibits minimum inhibitory concentrations (MICs) of 3.1 μg/mL for MRSA (ATCC BAA-1556), 3.1 μg/mL for S. aureus (ATCC 29213), 12.5 μg/mL for P. aeruginosa (ATCC 27883), and 25 μg/mL for E. coli (ATCC 25922) [1].
价 格:¥电议型 号:T76226产 地:中国大陆
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T75707BIM-26226;化合物 BIM-26226BIM-26226
BIM-26226, a gastrin-releasing peptide, serves as a potent and selective antagonist to the bombesin receptor, effectively inhibiting BN- or GRP-stimulated amylase release with IC50 values in the nanomolar range. It is utilized in cancer research [1] [2].
价 格:¥电议型 号:T75707产 地:中国大陆
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T72269TAK-960 dihydrochloride;化合物 TAK-960 dihydrochlorideTAK-960 dihydrochloride
TAK-960 dihydrochloride is an orally administered, selective polo-like kinase 1 (PLK1) inhibitor, exhibiting a potent IC 50 of 0.8 nM. It also targets PLK2 and PLK3 with IC 50 values of 16.9 and 50.2 nM, respectively. This compound effectively inhibits the proliferation of a broad range of cancer cell lines and demonstrates substantial efficacy against various tumor xenografts.
价 格:¥电议型 号:T72269产 地:中国大陆
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T72267Antitrypanosomal agent 9;化合物 Antitrypanosomal agent 9Antitrypanosomal agent 9
Antitrypanosomal agent 9 is a potent compound with inhibitory activity against T. b. brucei, exhibiting an IC50 of 1.15 μM. It is utilized in research for human African trypanosomiasis (HAT).
价 格:¥电议型 号:T72267产 地:中国大陆
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T72265Eltrombopag methyl ester;化合物 Eltrombopag methyl esterEltrombopag methyl ester
Eltrombopag Methyl Ester, a derivative of Eltrombopag, functions as a thrombopoietin (Tpo) receptor agonist to enhance platelet production and is employed in the study of certain thrombocytopenia variants.
价 格:¥电议型 号:T72265产 地:中国大陆
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T72263Antituberculosis agent-8;化合物 Antituberculosis agent-8Antituberculosis agent-8
Antituberculosis agent-8 is an antitubercular compound effective against M. tuberculosis H37Rv, demonstrating a minimum inhibitory concentration (MIC) of 3.53 μM (1.6 μg/mL). Additionally, it exhibits potent antifungal properties against A. niger, with an MIC of 62.50 μM.
价 格:¥电议型 号:T72263产 地:中国大陆