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T71188LY2780301；化合物 LY2780301LY2780301
LY2780301 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor LY2780301 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway, thereby leading to inhibition of cell proliferation and the induction of apoptosis in tumor cells. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signa
价 格：￥电议型 号：T71188产 地：中国大陆
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T70301GAT100；化合物 GAT100GAT100
GAT100 is a potent and covalent negative allosteric modulator (NAM). GAT-100 behaved as a robust positive allosteric modulator of binding of orthosteric agonist CP55,940. This novel covalent probe can serve as a useful tool for characterizing CB1R allosteric ligand-binding motifs.
价 格：￥电议型 号：T70301产 地：中国大陆
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T69577LEI-301；化合物 LEI-301LEI-301
LEI-301 is a novel potent inhibitor for the PLAAT family members, reducing the NAE levels, including anandamide, in cells overexpressing PLAAT2 or PLAAT5.
价 格：￥电议型 号：T69577产 地：中国大陆
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T69301Picumast dihydrochloride；化合物 Picumast dihydrochloridePicumast dihydrochloride
Picumast dihydrochloride is a prophylactically active anti-allergic compound which combines inhibition of mediator release and action. The activity profile of PDH differs clearly from that of known prophylactic anti-allergic drugs such as DSCG and ketotifen.
价 格：￥电议型 号：T69301产 地：中国大陆
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T68410CBM 301940；化合物 CBM 301940CBM 301940
CBM 301940 is a potent malonyl-CoA decarboxylase inhibitor that is orally bioavailable.
价 格：￥电议型 号：T68410产 地：中国大陆
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T68302KD3010 tosylate；化合物 KD3010 tosylateKD3010 tosylate
KD-3010 is a peroxisome proliferator-activated receptor delta agonist potentially for the treatment of diabetes and obesity. KD-3010 dramatically ameliorates liver injury induced by carbon tetrachloride (CCl(4)) injections. Deposition of extracellular matrix proteins was lower in the KD3010-treated group than in the vehicle- or GW501516-treated group. Interestingly, profibrogenic connective tissue growth factor was induced significantly by GW501516, but not by KD-3010, following CCl(4) treatmen
价 格：￥电议型 号：T68302产 地：中国大陆
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T68301Sulcardine sulfate trihydrate；化合物 Sulcardine sulfate trihydrateSulcardine sulfate trihydrate
Sulcardine sulfate trihydrate is a multi-ion channel blocker potentially for the treatment of arrhythmia.
价 格：￥电议型 号：T68301产 地：中国大陆
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T67301(2R,5R)-5-Benzyl-2-(tert-butyl)-3-methylimidazolidin-4-one；化合物 (2R,5R)-5-Benzyl-2-(tert-butyl)-3-met
(2R,5R)-5-Benzyl-2-(tert-butyl)-3-methylimidazolidin-4-one is a useful organic compound for research related to life sciences. The catalog number is T67301 and the CAS number is 390766-89-9.
价 格：￥电议型 号：T67301产 地：中国大陆
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T6681STF-083010；化合物STF083010STF083010；STF083010
STF-083010 is a selective inhibitor of the IRE1α endonuclease.
价 格：￥电议型 号：T6681产 地：中国大陆
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T66301(3S,8R,9S,10R,13S,14S)-17-Iodo-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopent
(3S,8R,9S,10R,13S,14S)-17-Iodo-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol is a useful organic compound for research related to life sciences. The catalog number is T66301 and the CAS number is 32138-69-5.
价 格：￥电议型 号：T66301产 地：中国大陆
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T6585SAR405838；化合物MI773MI773|||MI 773|||MI-77301|||MI-773；MI773|||MI 773|||MI-77301|||MI-773
MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.
价 格：￥电议型 号：T6585产 地：中国大陆
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T65301N-Methyl-1-(naphthalen-1-yl)methanamine；化合物 N-Methyl-1-(naphthalen-1-yl)methanamineN-Methyl-1-(napht
N-Methyl-1-(naphthalen-1-yl)methanamine is a useful organic compound for research related to life sciences. The catalog number is T65301 and the CAS number is 14489-75-9.
价 格：￥电议型 号：T65301产 地：中国大陆
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T64301VU6028418；化合物 VU6028418VU6028418
VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).
价 格：￥电议型 号：T64301产 地：中国大陆
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T63301CDK7-IN-18；化合物 CDK7-IN-18CDK7-IN-18
CDK7-IN-18 is a pyrimidine-derived compound that is a potent inhibitor of CDK7. CDK7-IN-18 exhibits potential for research in a variety of cancers, particularly those with dysregulated transcription.
价 格：￥电议型 号：T63301产 地：中国大陆
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T63019GKA50 quarterhydrate；化合物 GKA50 quarterhydrateGKA50 quarterhydrate
GKA50 quarterhydrate is a potent glucokinase activator with an EC50 value of 33 nM. GKA50 quarterhydrate is a glucose-like activator of β-cell metabolism in rodent and human pancreatic islets and a Ca2+-dependent regulator of insulin secretion. quarterhydrate stimulates insulin secretion in mouse islets and significantly reduces blood glucose in high-fat-fed female rats.
价 格：￥电议型 号：T63019产 地：中国大陆
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T63018HIV-1 inhibitor-43；化合物 HIV-1 inhibitor-43HIV-1 inhibitor-43
HIV-1 inhibitor-43 is a potent inhibitor of HIV-1, acting on HIV-1 Y188L (EC50: 21.3 nM), K103N-Y181C (EC50: 6.2 nM), K103N (EC50< 0.7 nM) and Y181C (EC50< 0.7 nM). HIV-1 inhibitor-43 reduces the expression of HIV-1 RNA and protein p24.
价 格：￥电议型 号：T63018产 地：中国大陆
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T63017SphK2-IN-2；化合物 SphK2-IN-2SphK2-IN-2
SphK2-IN-2 (21g) is a potent and selective inhibitor of SphK2 (IC50: 0.23 μM).
价 格：￥电议型 号：T63017产 地：中国大陆
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T63016Nrf2 activator-4；Nrf2 激活剂4Nrf2 activator-4
Nrf2 activator-4 is an Nrf2 activator that inhibits the production of reactive oxygen species in microglia for the treatment of fatty liver disease associated with metabolic dysfunction in humans.
价 格：￥电议型 号：T63016产 地：中国大陆
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T63015Pancreatic lipase/Carboxylesterase 1-IN-1；化合物 Pancreatic lipase/Carboxylesterase 1-IN-1Pancreatic li
Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent, dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A), acting on PL (IC50: 2.13 μM) and hCES1A (IC50: 0.055 μM).
价 格：￥电议型 号：T63015产 地：中国大陆
