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T63034IDO1-IN-13；化合物 IDO1-IN-13IDO1-IN-13
IDO1-IN-13 (compound 27a) is a potent inhibitor of IDO1 (IC50: 61.6 nM). Ido1-in-13 inhibits cell IDO1 with an EC50 value of 30 nM for HeLa. In SK-OV-3 xenograft tumor tissue, IDO1-IN-13 reduced kyn/trp ratio by 51%.
价 格：￥电议型 号：T63034产 地：中国大陆
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T63033MsbA-IN-4；化合物 MsbA-IN-4MsbA-IN-4
MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).
价 格：￥电议型 号：T63033产 地：中国大陆
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T63032P-gp modulator 2；化合物 P-gp modulator 2P-gp modulator 2
P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.
价 格：￥电议型 号：T63032产 地：中国大陆
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T63031PAK1-IN-1；化合物 PAK1-IN-1PAK1-IN-1
PAK1-IN-1 is a selective and potent inhibitor of PAK1 (IC50: 9.8 nM). PAK1-IN-1 inhibits PAK1-associated tumour cell migration and invasion in a dose-dependent manner.
价 格：￥电议型 号：T63031产 地：中国大陆
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T63030AR antagonist 2；化合物 AR antagonist 2AR antagonist 2
AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).
价 格：￥电议型 号：T63030产 地：中国大陆
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T6303CCT128930；化合物CCT128930CCT128930
CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.
价 格：￥电议型 号：T6303产 地：中国大陆
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T62303PDE4B/7A-IN-1；化合物 PDE4B/7A-IN-1PDE4B/7A-IN-1
Compound 22, a 5-hydroxynitrile rubber 7 receptor antagonist (5-HT1A Ki=8 nm, Kb=0.04 nm; 5-nitrile rubber 7K I=451 nm, Kb=460 nm), exhibits inhibitory activity against PDE4B/PDE7A (PDE4B IC50=80.4 μM; PDE7A IC50=151.3 μM). It demonstrates significant passive biofilm penetration capabilities and high metabolic stability in vitro. Pharmacological assessment has revealed precognitive and antidepressant effects in rat behavioral tests, highlighting its potential therapeutic applications.
价 格：￥电议型 号：T62303产 地：中国大陆
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T6210Pifithrin-μ；化合物Pifithrin-μPFTμ|||NSC 303580|||2-Phenylethynesulfonamide；PFTμ|||NSC 303580|||2-Phenyl
Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.
价 格：￥电议型 号：T6210产 地：中国大陆
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T61413Gü1303；化合物 Gü1303Gü1303
Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK). This compound effectively suppresses the autocatalytic activation of the CatK zymogen [1].
价 格：￥电议型 号：T61413产 地：中国大陆
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T61303MmpL3-IN-1；化合物 MmpL3-IN-1MmpL3-IN-1
MmpL3-IN-1, also known as compound 32, is a highly effective inhibitor of Mycobacterial membrane protein large 3 (MmpL3). With an anti-tuberculosis activity exhibiting a minimum inhibitory concentration (MIC) of less than 0.016 μg/mL in M. tuberculosis, MmpL3-IN-1 is a valuable compound for research on drug-resistant tuberculosis [1].
价 格：￥电议型 号：T61303产 地：中国大陆
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T6088Anidulafungin；阿尼芬净LY303366|||Eraxis|||Ecalta；LY303366|||Eraxis|||Ecalta|||阿尼芬净
Anidulafungin (Ecalta) (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity.
价 格：￥电议型 号：T6088产 地：中国大陆
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T60405GSK-3036656 free base；化合物 GSK3036656GSK656 HCl|||GSK 3036656|||GSK656|||GSK-3036656|||GSK-656|||GSK
GSK656 (GSK3036656) shows potent inhibition of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS) (IC50 = 0.20 μM) which has potential for the treatment of tuberculosis [1].
价 格：￥电议型 号：T60405产 地：中国大陆
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T60303Collagen-IN-1；化合物 Collagen-IN-1Collagen-IN-1
Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Collagen-IN-1 effectively reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelets. This compound holds promise for research into platelet-related thrombosis diseases [1].
价 格：￥电议型 号：T60303产 地：中国大陆
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T5303Isethionic acid sodium salt；羟乙基磺酸钠Sodium isethionate；Sodium isethionate|||羟乙基磺酸钠
Isethionic acid sodium salt (Sodium isethionate) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. Mammals are able to endogenously synthesize Isethionic acid sodium salt via taurine through a possible enzymatic deamination process. Isethionic acid sodium salt can be found in both human plasma and urine. Higher plasma levels of Isethionic acid sodium salt have been shown to be protective against type 2 diabetes.
价 格：￥电议型 号：T5303产 地：中国大陆
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T4988Boceprevir；波普瑞韦SCH 503034|||EBP 520；SCH 503034|||EBP 520|||波普瑞韦
Boceprevir (SCH 503034) is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-based replicon assay.
价 格：￥电议型 号：T4988产 地：中国大陆
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T4423LY 303511 hydrochloride；化合物LY303511 hydrochlorideLY303511 hydrochloride；LY303511 hydrochloride
LY 303511 hydrochloride is a potent mTOR inhibitor
价 格：￥电议型 号：T4423产 地：中国大陆
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T43034-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid；4-甲基-2-(4-三氟甲基苯基)噻唑-5-羧酸4-methyl-2-
4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid is used as a pharmaceutical intermediate.
价 格：￥电议型 号：T4303产 地：中国大陆
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T41303Isoflupredone；异氟泼尼松Delta-Fluorocortisone|||Isoflupredona|||Isoflupredonum|||9-Fluoroprednisolone；Del
Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expression of inflammatory mediators. Isoflupredone has anti-inflammatory and immunosuppressive effects and can be used to treat a variety of musculoskeletal, allergic and systemic inflammatory diseases.
价 格：￥电议型 号：T41303产 地：中国大陆
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T4063Delafloxacin；德拉沙星ABT492|||WQ-3034|||RX-3341；ABT492|||WQ-3034|||德拉沙星|||RX-3341
Delafloxacin (WQ-3034) (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. It has potent inhibitory against levofloxacin-resistant Streptococcus pneumoniae strains (MIC: 0.0078-0.125 μg/ml).
价 格：￥电议型 号：T4063产 地：中国大陆
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T403035-A-RU-PABC-Val-Cit-Fmoc；化合物 5-A-RU-PABC-Val-Cit-Fmoc5-A-RU-PABC-Val-Cit-Fmoc
5-A-RU-PABC-Val-Cit-Fmoc is one of the precursors of 5-A-RU, a small molecule mucosal-associated MAIT activator that is a precursor for bacterial synthesis of riboflavin.
价 格：￥电议型 号：T40303产 地：中国大陆
