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T63157Antifungal agent 16；化合物 Antifungal agent 16Antifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.
价 格：￥电议型 号：T63157产 地：中国大陆
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T63156SJ000025081；化合物 SJ000025081SJ000025081
SJ000025081 is a dihydropyridine and can be used as an antimalarial agent. In a mouse malaria model, SJ000025081 significantly inhibited parasitemia in P. yoelii infection.
价 格：￥电议型 号：T63156产 地：中国大陆
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T63155MMP-9-IN-3；化合物 MMP-9-IN-3MMP-9-IN-3
MMP-9-IN-3 is an MMP-9 inhibitor (IC50: 5.56 nM) that forms hydrogen bonds with MMP-9. MMP-9-IN-3 inhibits AKT activity (IC50: 2.11 nM). mmp-9-IN-3 is cytotoxic and induces apoptosis. mmp-9-IN-3 can be used to study cancer.
价 格：￥电议型 号：T63155产 地：中国大陆
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T63154Axl-IN-10；化合物 Axl-IN-10Axl-IN-10
Axl-IN-10 is a potent inhibitor of AXL (IC50: 5 nM).Axl-IN-10 has good pharmacokinetic properties in animals and excellent transmembrane properties.Axl-IN-10 can be used to study proliferative, allergic, autoimmune, inflammatory, transplant rejection, cancer or other mammalian diseases.
价 格：￥电议型 号：T63154产 地：中国大陆
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T63153APJ receptor agonist 5；化合物 APJ receptor agonist 5APJ receptor agonist 5
APJ receptor agonist 5 (compound 3) is a potent and orally active apelin receptor (APJ) agonist (EC 50:0.4 nM). APJ receptor agonist 5 has excellent pharmacokinetic profiles in rodent models of heart failure (HF) and an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 can improve cardiac function and can be used in the study of HF disease.
价 格：￥电议型 号：T63153产 地：中国大陆
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T63152Prexasertib Mesylate Hydrate；化合物 Prexasertib Mesylate HydratePrexasertib Mesylate Hydrate
Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is an ATP-competitive, selective, second generation cell cycle detection site kinase 1 (CHK1) inhibitor (IC50<1 nM, Ki: 0.9 nM). Prexasertib Mesylate Hydrate inhibits CHK2 (IC50: 8 nM) and RSK1 (IC50: 9 nM). prexasertib Mesylate Hydrate causes double-stranded DNA breaks and replication mutations, induces apoptosis and exhibits potent anti-tumour effects.
价 格：￥电议型 号：T63152产 地：中国大陆
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T63151IHCH-3064；化合物 IHCH-3064IHCH-3064
IHCH-3064 is a tumour immunotherapeutic agent that targets both the adenosine A2A receptor and HDAC. IHCH-3064 effectively binds A2AR (Ki: 2.2 nM) and selectively inhibits HDAC1 (IC50: 80.2 nM). Prexasertib Mesylate
价 格：￥电议型 号：T63151产 地：中国大陆
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T63150LY-411575 (isomer 3)；化合物 LY-411575 (isomer 3)LY-411575 (isomer 3)
LY-411575 isomer 3 is an isomer of LY411575. LY411575 is a potent γ-secretase inhibitor.
价 格：￥电议型 号：T63150产 地：中国大陆
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T6315MLN8054；化合物MLN8054MLN8054
MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.
价 格：￥电议型 号：T6315产 地：中国大陆
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T62610LY3154885；化合物 LY3154885LY3154885
LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).
价 格：￥电议型 号：T62610产 地：中国大陆
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T62315HPK1-IN-30；化合物 HPK1-IN-30HPK1-IN-30
HPK1-IN-30 is a potent inhibitor of HPK1. HPK1-IN-30 has potential for cancer disease research.
价 格：￥电议型 号：T62315产 地：中国大陆
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T6226Pemetrexed disodium hemipenta hydrate；培美曲塞二钠水合物Pemetrexed Disodium Hydrate|||LY-231514 Disodium Hydr
Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 65 nM, respectively.
价 格：￥电议型 号：T6226产 地：中国大陆
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T61315HDAC6/HSP90-IN-2；化合物 HDAC6/HSP90-IN-2HDAC6/HSP90-IN-2
HDAC6/HSP90-IN-2 (compound 6e) is a dual inhibitor targeting HDAC6 and Hsp90, exhibiting IC50 values of 105.7 nM and 61 nM, respectively. It is primarily utilized in cancer research [1].
价 格：￥电议型 号：T61315产 地：中国大陆
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T61306SRI-41315；化合物 SRI-41315SRI-41315
SRI-41315, a chemical compound, effectively addresses premature termination codons (PTCs) associated with cystic fibrosis in immortalized and primary human bronchial epithelial cells. It induces a prolonged pause at stop codons, resulting in the restoration of cystic fibrosis transmembrane conductance regulator (CFTR) expression and function. This compound achieves PTC suppression by reducing the abundance of the termination factor eRF1. Additionally, SRI-41315 synergistically enhances CFTR acti
价 格：￥电议型 号：T61306产 地：中国大陆
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T60315Anti-infective agent 1；化合物 Anti-infective agent 1Anti-infective agent 1
Anti-infective agent 1 (compound 3a) serves as a potent, selective antiprotozoal and antimycobacterial compound. It showcases antiparasitic efficacy against P. falciparum and T. brucei rhodesiense, demonstrating IC50 values of 10.95 and 0.06 μM, respectively. Moreover, it displays antimycobacterial properties against Mycobacterium smegmatis, exhibiting a minimum inhibitory concentration (MIC) of 8 μg/mL [1].
价 格：￥电议型 号：T60315产 地：中国大陆
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T5488ILK-IN-2；化合物OSU-T315OSU-T315；OSU-T315
ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.
价 格：￥电议型 号：T5488产 地：中国大陆
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T5485OSU-T315；化合物ILK-IN-2OSU-T315 (1,5-regioisomer)|||ILK-IN-2；OSU-T315 (1,5-regioisomer)|||ILK-IN-2
OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.
价 格：￥电议型 号：T5485产 地：中国大陆
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T5315TCA1；化合物TCA-1TCA-1|||TCA 1；TCA-1|||TCA 1
TCA1 (TCA 1) is a small molecule with activity against drug-resistant and persistent tuberculosis.
价 格：￥电议型 号：T5315产 地：中国大陆
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T4376Nampt-IN-1；化合物Nampt-IN-1LSN3154567；LSN3154567
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
价 格：￥电议型 号：T4376产 地：中国大陆
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T40315γ-Secretase modulator 10；γ-Secretase modulator 10γ-Secretase modulator 10
γ-Secretase modulator 10 is a novel γ-secretase modulator.
价 格：￥电议型 号：T40315产 地：中国大陆
