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T63270HPK1-IN-29;化合物 HPK1-IN-29HPK1-IN-29
HPK1-IN-29 is a potent inhibitor of HPK1, in which hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-29 is able to enhance anti-tumor immunity in humans and shows potential for the study of immune-related diseases, especially tumors.
价 格:¥电议型 号:T63270产 地:中国大陆
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T6327Tubacin;HDAC6 抑制剂Tubacin
Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.
价 格:¥电议型 号:T6327产 地:中国大陆
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T62436KY-02327 acetate;化合物 KY-02327 acetateKY-02327 acetate
KY-02327 acetate is a potent inhibitor of Dishevelled (Dvl)-CXXC5 interactions and is a metabolically stable analog of KY-02061. KY-02327 acetate activates the Wnt/β-catenin pathway, which in turn promotes osteoblast differentiation.
价 格:¥电议型 号:T62436产 地:中国大陆
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T62327HDAC2-IN-1;化合物 HDAC2-IN-1HDAC2-IN-1
HDAC2-IN-1 (Compound 17) is an orally active, competitive HDAC2 inhibitor (IC50: 0.5 μM) that crosses the blood-brain barrier. HDAC2-IN-1 also inhibits HDAC1 (IC50: 1.61 μM) and HDAC8 (IC50: 0.98 μM).
价 格:¥电议型 号:T62327产 地:中国大陆
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T61725VU0463271 quarterhydrate;化合物 VU0463271 quarterhydrateVU0463271 quarterhydrate
VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].
价 格:¥电议型 号:T61725产 地:中国大陆
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T6169Indirubin;靛玉红Indigopurpurin|||Indigo red|||NSC 105327|||Couroupitine B;Indigopurpurin|||Indigo red||
Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.
价 格:¥电议型 号:T6169产 地:中国大陆
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T61564PF-03463275;化合物PF-03463275PF-3463275;PF-3463275
PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS permeability and may be used to ameliorate cognitive deficits associated with schizophrenia.
价 格:¥电议型 号:T61564产 地:中国大陆
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T61327BRD4 Inhibitor-15;化合物 BRD4 Inhibitor-15BRD4 Inhibitor-15
BRD4 Inhibitor-15 (compound 13) is a highly potent and specific inhibitor of BRD4, effectively inhibiting it with an IC50 of 18 nM. By regulating the Bcl-2/Bax proteins and activating the caspase-3 signaling pathway, BRD4 Inhibitor-15 induces apoptosis of 22RV1 cells. Additionally, it effectively down-regulates the c-Myc level in 22RV1 cells. Due to its properties, BRD4 Inhibitor-15 is a valuable compound for research related to prostate cancer [1].
价 格:¥电议型 号:T61327产 地:中国大陆
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T61024PK9327;化合物 PK9327PK9327
PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.
价 格:¥电议型 号:T61024产 地:中国大陆
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T60327Falimint;化合物 FalimintFalimint
Falimint is a compound with antipyretic and analgesic activity [1].
价 格:¥电议型 号:T60327产 地:中国大陆
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T6007Birinapant比瑞那帕TL32711|||比瑞那帕
Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
价 格:¥电议型 号:T6007产 地:中国大陆
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T5470LAZABEMIDE;拉扎贝胺Ro 19-6327;拉扎贝胺|||Ro 19-6327
Lazabemide (Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
价 格:¥电议型 号:T5470产 地:中国大陆
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T5327Amezinium methylsulfate;甲磺美嗪Amezinium metilsulfate|||Amezinium (methylsulfate)|||Lu-1631;Amezinium m
Amezinium methylsulfate (Lu-1631) has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.
价 格:¥电议型 号:T5327产 地:中国大陆
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T4327Prexasertib dihydrochloride;化合物Prexasertib dihydrochlorideLY2606368 (dihydrochloride)|||Prexasertib
Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.
价 格:¥电议型 号:T4327产 地:中国大陆
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T4261BPR1J-097 hydrochloride (1327167-19-0(free base));化合物BPR1J-097 hydrochlorideBPR1J-097 hydrochloride
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
价 格:¥电议型 号:T4261产 地:中国大陆
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T4252ML327;化合物ML327ML327
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
价 格:¥电议型 号:T4252产 地:中国大陆
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T40327Tetra-N-acetylchitotetraose;Tetra-N-acetylchitotetraoseTetra-N-acetylchitotetraose
Tetra-N-acetylchitotetraose, a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia, stimulates plant defense systems. Moreover, it serves as a substrate for the CO deacetylase nodulation protein NodB in Rhizobium leguminosarum.
价 格:¥电议型 号:T40327产 地:中国大陆
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T39611EnuvaptanEnuvaptanEnuvaptan|||BAY-2327949
Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases.
价 格:¥电议型 号:T39611产 地:中国大陆
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T39508KY-02327;化合物KY-02327KY-02327
KY-02327, a metabolically stabilized analog of KY-02061, serves as a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction. This compound activates the Wnt/β-catenin pathway, thereby promoting osteoblast differentiation.
价 格:¥电议型 号:T39508产 地:中国大陆
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T39327AmdizalisibAmdizalisibAmdizalisib|||HMPL-689
Amdizalisib is a PI3K inhibitor and used for the research of inflammatory disease, autoimmune disease or cancer.
价 格:¥电议型 号:T39327产 地:中国大陆