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T5671Isophorone;异佛尔酮Isophorone
Isophorone is a clear liquid that smells like peppermint. It can be dissolved in water and evaporates somewhat faster than water.
价 格:¥电议型 号:T5671产 地:中国大陆
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T5670Isobutylparaben;尼泊金异丁酯Isobutylparaben
Isobutylparaben is a preservative and preservative insecticide.
价 格:¥电议型 号:T5670产 地:中国大陆
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T5567Tetradecanedioic acid;十四烷二酸Tetradecanedicarboxylate;十四烷二酸|||Tetradecanedicarboxylate
Tetradecanedioic acid (Tetradecanedicarboxylate) is a long-chain fatty acid that is a type of endogenous metabolite. It can serve as a candidate biomarker for drug-drug interactions mediated by organic anion transporting peptides.
价 格:¥电议型 号:T5567产 地:中国大陆
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T5056PF-4800567;化合物PF-4800567PF-4800567
PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.
价 格:¥电议型 号:T5056产 地:中国大陆
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T4567Sulfaphenazole磺胺苯吡唑Plisulfan|||Raziosulfa|||Depocid|||磺胺苯吡唑|||Depotsulfonamide
Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19). At 10 μM, sulfaphenazole has been shown to inhibit endothelium-derived hyperpolarizing factor synthase, a CYP450 isozyme in the porcine coronary artery homologous to CYP2C8/9 that generates reactive oxygen species in coronary endothelial cells and modulates
价 格:¥电议型 号:T4567产 地:中国大陆
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T4376Nampt-IN-1;化合物Nampt-IN-1LSN3154567;LSN3154567
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
价 格:¥电议型 号:T4376产 地:中国大陆
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T4298JNJ-47965567;化合物JNJ-47965567JNJ-479655;JNJ-479655
JNJ-47965567 (JNJ-479655) is a selective antagonist of the purinergic receptor P2X subtype 7 (P2X7), a ligand-gated ion channel(with pKis of 7.9 and 8.7 for human and rat P2X7, respectively).
价 格:¥电议型 号:T4298产 地:中国大陆
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T405672,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol;2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol2,6,6-Trimethylbicy
2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol is isolated from Chrysanthemum indicum L..
价 格:¥电议型 号:T40567产 地:中国大陆
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T4029BTB-1;化合物BTB1BTB 1|||NSC156750;BTB 1|||NSC156750
BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.
价 格:¥电议型 号:T4029产 地:中国大陆
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T39567HDAC1/2-IN-3HDAC1/2-IN-3HDAC1/2-IN-3
HDAC1/2-IN-3 is an inhibitor of both HDAC1 and HDAC2, demonstrating IC50 values of 0-5 nM and 5-10 nM, respectively.
价 格:¥电议型 号:T39567产 地:中国大陆
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T38567STh;SThSTh
STh, also known as Escherichia coli heat-stable toxin, is a 19 amino acid polypeptide containing three disulfide bridges. It serves as an antigen of significance in the quest for a comprehensive enterotoxigenic Escherichia coli (ETEC) vaccine.
价 格:¥电议型 号:T38567产 地:中国大陆
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T3701MCC950;化合物MCC950CP-456773;CP-456773
CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically inhibited activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes. MCC950 reduced IL-1β production in vivo and attenuated the severity of experimental autoimmune encephalomyelitis (EAE), a
价 格:¥电议型 号:T3701产 地:中国大陆
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T36533SCH 725674;SCH 725674SCH 725674
SCH 725674 is an antifungal macrolide originally isolated from Aspergillus. It inhibits the growth of S. cerevisiae and C. albicans in vitro (MICs = 8 and 32 μg/ml, respectively).
价 格:¥电议型 号:T36533产 地:中国大陆
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T36086CAY10567CAY10567CAY-10567|||CAY10567
CAY10567 has a wide range of applications in life science related research.
价 格:¥电议型 号:T36086产 地:中国大陆
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T356792,4-Dichlorobenzenesulfonyl chloride;2,4-Dichlorobenzenesulfonyl chloride2,4-Dichlorobenzenesulfonyl
2,4-Dichlorobenzenesulfonyl chloride is a heterocyclic building block.1It has been used in the synthesis of nicotinyl arylsulfonylhydrazides that have anticancer and antibacterial activitiesin vitro.
价 格:¥电议型 号:T35679产 地:中国大陆
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T356782,3-Indolobetulinic glycine amide;2,3-Indolobetulinic glycine amide2,3-Indolobetulinic glycine amide
2,3-Indolobetulinic glycine amide is a pentacyclic triterpene and derivative of betulinic acid .1It has been used in the synthesis of betulinic acid derivatives with anticancer activity.
价 格:¥电议型 号:T35678产 地:中国大陆
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T356772,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester;2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester2,3,4
2,3,4-Tri-O-acetyl-β-D-glucuronide methyl ester is a synthetic intermediate in the synthesis of prodrug forms of the antitumor antibiotic daunomycin .1
价 格:¥电议型 号:T35677产 地:中国大陆
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T3567617β-hydroxy Exemestane;17β-hydroxy Exemestane17β-hydroxy Exemestane
17β-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17β-hydroxy Exemestane is an aromatase inhibitor (IC50 = 69 nM using human placental microsomes) and an androgen receptor (AR) agonist (IC50 = 39.6 nM) that is selective for AR over estrogen receptor α (ERα; IC50 = 21.2 μM). It stimulates growth of AR- and ERα-positive MCF-7 (EC50 = 2.7 μM) and T47D breast cancer cells (EC50s =
价 格:¥电议型 号:T35676产 地:中国大陆
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T35675SW203668 (trifluoroacetate salt)SW203668 (trifluoroacetate salt)SW-203668 (trifluoroacetate salt)|||
SW203668 is an irreversible inhibitor of stearoyl-CoA desaturase (IC50 = 54 nM). It is selectively cytotoxic to H2122, H460, HCC44, and HCC95 cell lines that express cytochrome P450 (CYP) isoform CYP4F11 over eight other cancer cell lines that lack CYP4F11 in vitro (IC50s = 22-116 and >10,000 nM, respectively) and ectopic expression of CYP4F11 in SW203668-insensitive H1155 cells results in sensitization to SW203668.
价 格:¥电议型 号:T35675产 地:中国大陆
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T35674StRIP16;StRIP16StRIP16
Rab8a GTPase-binding stapled peptide (Kd = 12.7 μM). Cell permeable; localizes to the endomembrane system.
价 格:¥电议型 号:T35674产 地:中国大陆